Azab AK, Hu J, Quang P, Azab F, Pitsillides C, Awwad R, Thompson B, Maiso P, Sun JD, Hart CP, Roccaro AM, Sacco A, Ngo HT, Lin CP, Kung AL, Carrasco RD, Vanderkerken K, Ghobrial IM. Hypoxia promotes dissemination of multiple myeloma through acquisition of endothelial to mesenchymal transition-like features. Blood. 2012 Mar 6. [Epub ahead of print]
Azab AK, Quang P, Azab F, Pitsillides C, Thompson B, Chonghaile T, Patton JT, Maiso P, Monrose V, Sacco A, Ngo HT, Flores LM, Lin CP, Magnani JL, Kung AL, Letai A, Carrasco R, Roccaro AM, Ghobrial IM. P-selectin glycoprotein ligand regulates the interaction of multiple myeloma cells with the bone marrow microenvironment. Blood. 2012 Feb 9;119(6):1468-78. Epub 2011 Nov 16.
McCarthy JR, Sazonova IY, Erdem SS, Hara T, Thompson BD, Patel P, Botnaru I, Lin CP, Reed GL, Weissleder R, Jaffer FA. Multifunctional nanoagent for thrombus-targeted fibrinolytic therapy. Nanomedicine (Lond). 2012 Feb 21. [Epub ahead of print]
Park D, Spencer JA, Koh BI, Kobayashi T, Fujisaki J, Clemens TL, Lin CP, Kronenberg HM, Scadden DT. Endogenous bone marrow MSCs are dynamic, fate-restricted participants in bone maintenance and regeneration. Cell Stem Cell. 2012 Mar 2;10(3):259-72.
Zettergren E, Vickers D, Runnels J, Murthy SK, Lin CP, Niedre M. Instrument for fluorescence sensing of circulating cells with diffuse light in mice in vivo. J Biomed Opt. 2012 Mar;17(3):037001.
Zhang L, Alt C, Li P, White RM, Zon LI, Wei X, Lin CP. An optical platform for cell tracking in adult zebrafish. Cytometry A. 2012 Feb;81(2):176-82.
Ashida N, Senbanerjee S, Kodama S, Foo SY, Coggins M, Spencer JA, Zamiri P, Shen D, Li L, Sciuto T, Dvorak A, Gerszten RE, Lin CP, Karin M, Rosenzweig A. IKKβ regulates essential functions of the vascular endothelium through kinase-dependent and -independent pathways. Nat Commun. 2011 May;2:318.
Ferraro F, Lymperi S, Méndez-Ferrer S, Saez B, Spencer JA, Yeap BY, Masselli E, Graiani G, Prezioso L, Rizzini EL, Mangoni M, Rizzoli V, Sykes SM, Lin CP, Frenette PS, Quaini F, Scadden DT. Diabetes impairs hematopoietic stem cell mobilization by altering niche function. Sci Transl Med. 2011 Oct 12;3(104):104ra101.
Fujisaki J, Wu J, Carlson AL, Silberstein L, Putheti P, Larocca R, Gao W, Saito TI, Lo Celso C, Tsuyuzaki H, Sato T, Côté D, Sykes M, Strom TB, Scadden DT, Lin CP. In vivo imaging of Treg cells providing immune privilege to the haematopoietic stem-cell niche. Nature. 2011 Jun 8;474(7350):216-9
Imitola J, Coté D, Rasmussen S, Xie XS, Liu Y, Chitnis T, Sidman RL, Lin CP, Khoury SJ. Multimodal coherent anti-Stokes Raman scattering microscopy reveals microglia-associated myelin and axonal dysfunction in multiple sclerosis-like lesions in mice. J Biomed Opt. 2011 January/February;16(2):021109.
Lane SW, Wang YJ, Lo Celso C, Ragu C, Bullinger L, Sykes SM, Ferraro F, Shterental S, Lin CP, Gilliland DG, Scadden DT, Armstrong SA, Williams DA. Differential niche and Wnt requirements during acute myeloid leukemia progression. Blood. 2011 Sep 8;118(10):2849-56.
Lo Celso C, Lin CP, Scadden DT. In vivo imaging of transplanted hematopoietic stem and progenitor cells in mouse calvarium bone marrow. Nat Protoc. 2011 Jan;6(1):1-14.
Maiso P, Liu Y, Morgan B, Azab AK, Ren P, Martin MB, Zhang Y, Liu Y, Sacco A, Ngo H, Azab F, Quang P, Rodig SJ, Lin CP, Roccaro AM, Rommel C, Ghobrial IM. Defining the role of TORC1/2 in multiple myeloma. Blood. 2011 Dec 22;118(26):6860-70.
Pitsillides CM, Runnels JM, Spencer JA, Zhi L, Wu MX, Lin CP. Cell labeling approaches for fluorescence-based in vivo flow cytometry. Cytometry A. 2011 Oct;79(10):758-65.
Runnels JM, Carlson AL, Pitsillides C, Thompson B, Wu J, Spencer JA, Kohler JM, Azab A, Moreau AS, Rodig SJ, Kung AL, Anderson KC, Ghobrial IM, Lin CP. Optical techniques for tracking multiple myeloma engraftment, growth, and response to therapy. J Biomed Opt. 2011 Jan-Feb;16(1):011006.
Sarkar D, Spencer JA, Phillips JA, Zhao W, Schafer S, Spelke DP, Mortensen LJ, Ruiz JP, Vemula PK, Sridharan R, Kumar S, Karnik R, Lin CP, Karp JM. Engineered cell homing. Blood. 2011 Dec 15;118(25):e184-91.
Sun J, Gao Y, Isaacs RJ, Boelte KC, Lin CP, Boczko EM, Li D. Simultaneous On-Chip DC Dielectrophoretic Cell Separation and Quantitative Separation Performance Characterization. Anal Chem. 2012 Jan 9. [Epub ahead of print]
Zettergren E, Vickers D, Runnels J, Lin CP, Niedre MJ. Validation of a device for fluorescence sensing of rare circulating cells with diffusive light in an optical flow phantom model. Conf Proc IEEE Eng Med Biol Soc. 2011 Aug;2011:486-9.
Zhao W, Schafer S, Choi J, Yamanaka YJ, Lombardi ML, Bose S, Carlson AL, Phillips JA, Teo W, Droujinine IA, Cui CH, Jain RK, Lammerding J, Love JC, Lin CP, Sarkar D, Karnik R, Karp JM. Cell-surface sensors for real-time probing of cellular environments. Nat Nanotechnol. 2011 Jul 17;6(8):524-31.
Zhi L, Kim P, Thompson BD, Pitsillides C, Bankovich AJ, Yun SH, Lin CP, Cyster JG, Wu MX. FTY720 blocks egress of T cells in part by abrogation of their adhesion on the lymph node sinus. J Immunol. 2011 Sep 1;187(5):2244-51.
Fan Z, Spencer JA, Lu Y, Pitsillides CM, Singh G, Kim P, Yun SH, Toxavidis V, Strom TB, Lin CP, Koulmanda M. In vivo tracking of 'color-coded' effector, natural and induced regulatory T cells in the allograft response. Nat Med. 2010 Jun;16(6):718-22. Epub 2010 May 23.
Horner BM, Ferguson KK, Randolph MA, Spencer JA, Carlson AL, Hirsh EL, Lin CP, Butler PE. In vivo observations of cell trafficking in allotransplanted vascularized skin flaps and conventional skin grafts. J Plast Reconstr Aesthet Surg. 2010 Apr;63(4):711-9. Epub 2009 Mar 26.
Li C, Pastila RK, Pitsillides C, Runnels JM, Puoris'haag M, Côté D, Lin CP. Imaging leukocyte trafficking in vivo with two-photon-excited endogenous tryptophan fluorescence. Opt Express. 2010 Jan 18;18(2):988-99.
Li C, Pitsillides C, Runnels JM, Côté D, Lin CP. Multiphoton microscopy of live tissue with ultraviolet autofluorescence. IEEE J Select Topics Quantum Electronics. 2010;16(3):516-523.
Raaijmakers MH, Mukherjee S, Guo S, Zhang S, Kobayashi T, Schoonmaker JA, Ebert BL, Al-Shahrour F, Hasserjian RP, Scadden EO, Aung Z, Matza M, Merkenschlager M, Lin C, Rommens JM, Scadden DT. Bone progenitor dysfunction induces myelodysplasia and secondary leukaemia. Nature. 2010 Apr 8;464(7290):852-7. Epub 2010 Mar 21.
Saito TI, Fujisaki J, Carlson AL, Lin CP, Sykes M. Persistence of donor-derived protein in host myeloid cells after induced rejection of engrafted allogeneic bone marrow cells. Exp Hematol. 2010 Apr;38(4):333-9. Epub 2010 Feb 16.
Tsigkou O, Pomerantseva I, Spencer JA, Redondo PA, Hart AR, O'Doherty E, Lin Y, Friedrich CC, Daheron L, Lin CP, Sundback CA, Vacanti JP, Neville C. Engineered vascularized bone grafts. Proc Natl Acad Sci U S A. 2010 Feb 23;107(8):3311-6. Epub 2010 Feb 2.
Adams GB, Alley IR, Chung UI, Chabner KT, Jeanson NT, Celso CL, Marsters ES, Chen M, Weinstein LS, Lin CP, Kronenberg HM, Scadden DT. Haematopoietic stem cells depend on Galpha(s)-mediated signalling to engraft bone marrow. Nature 2009 May 7;459(7243):103-7. Epub 2009 Mar 25.
Azab AK, Azab F, Blotta S, Pitsillides CM, Thompson B, Runnels JM, Roccaro AM, Ngo HT, Melhem MR, Sacco A, Jia X, Anderson KC, Lin CP, Rollins BJ, Ghobrial IM. RhoA and Rac1 GTPases play major and differential roles in stromal cell-derived factor-1-induced cell adhesion and chemotaxis in multiple myeloma. Blood. 2009 Jul 16;114(3):619-29. Epub 2009 May 14.
Azab AK, Runnels JM, Pitsillides C, Moreau AS, Azab F, Leleu X, Jia X, Wright R, Ospina B, Carlson AL, Alt C, Burwick N, Roccaro AM, Ngo HT, Farag M, Melhem MR, Sacco A, Munshi NC, Hideshima T, Rollins BJ, Anderson KC, Kung AL, Lin CP, Ghobrial IM. The CXCR4 inhibitor AMD3100 disrupts the interaction of multiple myeloma cells with the bone marrow microenvironment and enhances their sensitivity to therapy. Blood 2009 Apr 30;113(18):4341-51. Epub 2009 Jan 12.
Henry FP, Côté D, Randolph MA, Rust EA, Redmond RW, Kochevar IE, Lin CP, Winograd JM. Real-time in vivo assessment of the nerve microenvironment with coherent anti-Stokes Raman scattering microscopy. Plast Reconstr Surg 2009 Feb;123(2 Suppl):123S-30S.
Horner BM, Ferguson KK, Randolph MA, Spencer JA, Carlson AL, Hirsh EL, Lin CP, Butler PE. In vivo observations of cell trafficking in allotransplanted vascularized skin flaps and conventional skin grafts. J Plast Reconstr Aesthet Surg 2009 Mar 24. [Epub ahead of print]
Lo Ceslo C, Fleming HE, Wu JW, Zhao CX,Miake-Lye S, Fujisaki J, Côte D, Rowe DW, Lin CP, Scadden DT. Live-animal tracking of individual haematopoietic stem/progenitor cells in their niche. Nature 2009 Jan 1;457(7225):92-6. Epub 2008 Dec 3.; 07434.3d.
Lo Celso C, Wu JW, Lin CP. In vivo imaging of hematopoietic stem cells and their microenvironment. J Biophotonics. 2009 Nov;2(11):619-31.
Roccaro AM, Sacco A, Thompson B, Leleu X, Azab AK, Azab F, Runnels J, Jia X, Ngo HT, Melhem MR, Lin CP, Ribatti D, Rollins BJ, Witzig TE, Anderson KC, Ghobrial IM. MicroRNAs 15a and 16 regulate tumor proliferation in multiple myeloma. Blood. 2009 Jun 25;113(26):6669-80. Epub 2009 Apr 28.
Kim P, Puoris'haag M, Coté D, Lin CP, Yun SH. In vivo confocal and multiphoton microendoscopy. J Biomed Opt 2008;13(1):010501-1-3.
Sackstein R, Merzaban JS, Cain DW, Dagia NM, Spencer JA, Lin CP, Wohlgemuth R. Ex vivo glycan engineering of CD44 programs human multipotent mesenchymal stromal cell trafficking to bone. Nat Med 2008; 14:181-187.
Veilleux I, Spencer JA, Biss DA, Cote D, Lin CP. In vivo cell tracking with video rate multimodality laser scanning microscopy. IEEE J Sel Top Quant Electron 2008;14(1):10-18.
Alsayed Y, Ngo H, Runnels J, Leleu X, Singha UK, Pitsillides CM, Spencer JA, Kimlinger T, Ghobrial JM, Jia X, Lu G, Timm M, Kumar A, Cote D, Veilleux I, Hedin KE, Roodman GD, Witzig TE, Kung AL, Hideshima T, Anderson KC, Lin CP, Ghobrial IM. Mechanisms of regulation of CXCR4/SDF-1 (CXCL12) dependent migration and homing in multiple myeloma. Blood 2007; 109:2708-17.
Alt C, Veilleux I, Lee H, Pitsillides CM, Cote D, Lin CP. Retinal flow cytometer. Opt Lett 2007; 32:3450-52.
Biss DP, Sumorok D, Burns SA, Webb RH, Zhou Y, Bifano TG, Cote D, Veilleux I, Zamiri P, Lin CP. In vivo fluorescent imaging of the mouse retina using adaptive optics. Opt Lett 2007;32(6):659-61.
Bogdanov AA Jr, Lin CP, Kang HW. Optical imaging of the adoptive transfer of human endothelial cells in mice using anti-human CD31 monoclonal antibody. Pharm Res 2007;24(6):1186-92. (Epub Mar 21 2007)
Boutrus S, Greiner C, Hwu D, Chan M, Kuperwasser C, Lin CP, Georgakoudi I. Portable two-color in vivo flow cytometer for real-time detection of fluorescently-labeled circulating cells. J Biomed Opt 2007;12(2):020507.
Framme C, Alt C, Schnell S, Sherwood M, Brinkmann R, Lin CP. Selective targeting of the retinal pigment epithelium in rabbit eyes with a scanning laser beam. Invest Ophthalmol Vis Sci 2007;48(4):1782-92.
Lee H, Alt C, Pitsillides C, Lin CP. Optical detection of intracellular cavitation during selective laser targeting of the retinal pigment epithelium: Dependence of cell death mechanism on pulse duration. J Biomed Opt 2007; 12(6), 064034.
Chakraverty R, Cote D, Buchli J, Cotter P, Hsu R, Zhao G, Sachs T, Pitsillides C, Bronson R, Means T, Lin C, Sykes M. An inflammatory checkpoint regulates recruitment of graft-versus-host reactive T cells to peripheral tissues. J Exp Med 2006; 203(8):2021-31.
Dagia NM, Gadhoum SZ, Knoblauch CA, Spencer JA, Zamiri P, Lin CP, Sackstein R. G-CSF induces E-selectin ligand expression on human myeloid cells. Nat Med 2006; 12(10):1185-90.
Lee H, Alt C, Pitsillides C, Puoris'haag M, Lin CP. In vivo imaging flow cytometer. Opt Exp 2006; 14(17): 7789-800.
Runnels JM, Zamiri P, Spencer JA, Veilleux I, Wei X, Bogdanov A, Lin CP. Imaging molecular expression on vascular endothelial cells by in vivo immunofluorescence microscopy. Mol Imaging 2006; 5(1):31-40.
Alt C, Framme C, Schnell S, Lee H, Brinkmann R, Lin CP. Selective targeting of the retinal pigment epithelium using an acousto-optic laser scanner. J Biomed Opt 2005;10(6):64014.
Evans CL, Potma EO, Puoris'haag M, Côté D, Lin CP , Xie XS. Chemical imaging of tissue In-vivo with video-rate coherent anti-stokes Raman scattering microscopy. Proc Natl Acad Sci USA 2005;102(46):16807-12.
Framme C, Alt C, Schnell S, Brinkman R, Lin CP. Selektive Behandlung des RPE unter Verwendung eines gescannten CW-Laserstrahls im Kaninchenmodell. Ophthalmologe 2005;102:491-6.
Sipkins DA, Wei X, Wu JW, Runnels JM, Cote D, Means TK, Luster AD, Scadden DT, Lin CP. In-vivo imaging of specialized bone marrow endothelial microdomains for tumor engraftment. Nature 2005;435:969-73.
Wei X, Sipkins DA, Pitsillides CM, Novak J, Georgakoudi I, Lin CP. Real-time detection of circulating apoptotic cells by In-vivo flow cytometry. Mol Imag 2005;10:1-2.
Georgakoudi I, Solban N, Novak J, Rice WL, Wei X, Hasan T, Lin CP. In-vivo flow cytometry: a new method for enumerating circulating cancer cells. Cancer Res 2004;64:5044-7.
Novak J, Georgakoudi I, Wei X, Prossin A, Lin CP. In-vivo flow cytometer for real-time detection and quantification of circulating cells. Opt Lett 2004;29(1):77-9.
Roegener J, Brinkmann R, Lin CP. Pump-probe detection of laser-induced microbubble formation in retinal pigment epithelium cells. J Biomed Opt 2004;9(2):367-71.
Brinkmann R, Koop N, Özdemir M, Alt C, Schüle G, Lin CP, Birngruber R. Targeting of the retinal pigment epithelium (RPE) by means of a rapidly scanned continuous wave (CW) laser beam. Laser Surg Med 2003; 32:252-264.
Pitsillides CM, Joe EK, Wei X, Anderson RR, Lin CP. Selective cell targeting with light-absorbing microparticles and nanoparticles. Biophys J 2003; 84:4023-4032.
Wei X, Runnels JM, Lin CP. Selective uptake of indocyanine green labels reticulocytes in circulation. Invest Ophthalmol Vis Sci 2003; 44(10):4489-4496.
Bogdanov AA Jr, Lin CP, Matuszewski L, Weissleder R. Cellular activation of self-quenched fluorescent reporter probe in tumor microenvironment. Neoplasia 2002; 4:228-236.
Hooper BA, Domankevitz Y, Anderson RR, Lin CP. Optical temperature probe. Appl Phys Lett 2001; 76:2381-2383.
Leszczynski D, Pitsillides CM, Pastila RK, Anderson RR, Lin CP. Laser-beam-triggered microcavitation: a novel method for selective cell destruction. Radiat Res 2001; 156:399-407.
Brinkmann R, Hüttmann G, Rögener J, Roider J, Birngruber R, Lin CP. Origin of retinal pigment epithelium cell damage by pulsed laser irradiance in the nanosecond to microsecond time regimen. Lasers Surg Med 2000; 27:451-464.
Domankevitz Y, Waldman J, Lin CP, Anderson RR. Selective delivery of laser energy to biological tissue based on refractive-index differences. Opt Lett 2000; 25:1104-1106.
Lin CP, Lynch MA, Kochevar IE. Reactive oxidizing species produced near the plasma membrane induce apoptosis in bovine aorta endothelial cells. Exp Cell Res 2000; 259:351-359.
Lin CP, Webb RH. Fiber-coupled multiplexed confocal microscope. Opt Lett 2000; 25:954-957.
