2012
Apidianakis Y, Que YA, Xu W, Tegos GP, Zimniak P, Hamblin MR, Tompkins RG, Xiao W, Rahma LG. Down-regulation of glutatione S-transferase alpha 4 (hGSTA4) in the muscle of thermally injured patients is indicative of susceptibility to bacterial infection. FASEB J. 2012 Feb;26(2):730-7. Epub 2011 Oct 28.
Chung H, Dai T, Sharma SK, Huang YY, Carroll JD, Hamblin MR. The Nuts and Bolts of Low-level Laser (Light) Therapy. Ann Biomed Eng. 2012 Feb;40(2):516-33. Epub 2011 Nov 2.
Dai T, Vrahas MS, Murray CK, Hamblin MR. Ultraviolet C irradiation: an alternative antimicrobial approach to localized infections? Expert Rev Anti-Infect Ther. 2012; 10(2):185-95.
Dai T, Fuchs BB, Coleman JJ, Prates RA, Astrakas C, St.Denis TG, Ribeiro MS, Mylonakis E, Hamblin MR, Tegos GP. Concepts and principles of photodynamic therapy as an alternative antifungal discovery platform. Front. Microbio. 2012 April;3(120). PMCID: PMC3322354
Demidova-Rice TN, Wolf L, Deckenback J, Hamblin MR, Herman IM. Human Platelet-Rich Plasma- and Extracellular Matrix-Derived Peptides Promote Impaired Cutaneous Wound Healing In Vivo. PLoS ONE. 2012;7(2):e32146. PMCID: PMC3285658
Hamblin MR. Antimicrobial Photodynamic Therapy and Photodynamic Inactivation, or Killing Bugs with Dyes and Light-A Symposium-in-Print. Photochem Photobiol. 2012 Apr 12. Epub ahead of print
Huang YY, Sharma SK, Carroll JD, Hamblin MR. Biphasic dose response in low-level light therapy - An update. Dose Response Journal. 2011; 9(4): 602-618.
Li P, Zhou G, Zhu X, Li G, Yan P, Shen L, Xu Q, Hamblin MR. Photodynamic therapy with hyperbranched poly(ether-ester) chlorin(e6) nanoparticles on human tongue carcinoma CAL-27 cells. Photodiagnosis Photodyn Ther. 2012 Mar;9(1):76-82. Epub 2011 Oct 4.
Penjweini R, Loew HG, Hamblin MR, Kratky KW. Long-term monitoring of live cell proliferation in presence of PVP-Hypericin: a new strategy using ms pulses of LED and the fluorescent dye CFSE. J Microsc. 2012 Jan;245(1):100-8.
Tanaka M, Kinoshita M, Yoshihara Y, Shinomiya N, Seki S, Nemoto K, Hirayama T, Dai T, Huang L, Hamblin MR, Morimoto Y. Optimal Photosensitizers for Photodynamic Therapy of Infections Should Kill Bacteria but Spare Neutrophils. Photochem Photobiol. 2012 Jan;88(1):227-232.
Vera DM, Haynes MH, Ball AR, Dai DT, Astrakas C, Kelso MJ, Hamblin MR, Tegos GP. Strategies to potentiate antimicrobial photoinactivation by overcoming resistant phenotypes(†). Photochem Photobiol. 2012 Jan 13. [Epub ahead of print]
Wang M, Huang L, Sharma SK, Jeon S, Thota S, Sperandio FF, Nayka SN, Chang J, Hamblin MR, Chiang LY. Synthesis and Photodynamic Effect of New Highly Photostable Decacationically Armed [60]- and [70]Fullerene Decaiodide Monoadducts to Target Pathogenic Bacteria and Cancer Cells. J Med Chem. 2012 Apr 26. [Epub ahead of print]
Wu Q, Xuan W, Ando T, Xu T, Huang L, Huang YY, Dai T, Dhital S, Sharma SK, Whalen MJ, Hamblin MR. Low-level laser therapy for closed-head traumatic brain injury in mice: effect of different wavelengths. Lasers Surg Med. 2012 Mar;44(3):218-26. Epub 2012 Jan 24.
2011
Agostinis P, Berg K, Cengel KA, Foster TH, Girotti AW, Gollnick SO, Hahn SM, Hamblin MR, Juzeniene A, Kessel D, Korbelik M, Moan J, Mroz P, Nowis D, Piette J, Wilson BC, Golab J. Photodynamic therapy of cancer: An update. CA Cancer J Clin. 2011 Jul-Aug;61(4):250-81. PMCID: PMC3209659
Chen AC, Arany P, Huang YY, Tomkinson EM, Sharma SK Kharkwal GB, Saleem T, Mooney D, Yull FE, Blackwell TS, Hamblin MR. Low-level laser therapy activates NF-kB via generation of reactive oxygen species in mouse embryonic fibroblasts. PLoS ONE, 2011, 6 (7) e22453.
Chen AC, Huang YY, Sharma SK, Hamblin MR. Effects of 810-nm Laser on Murine Bone-Marrow-Derived Dendritic Cells. Photomed Laser Surg. 2011 Jun;29(6):383-9.
Dai T, Bil de Arce VJ, Tegos GP, Hamblin MR. Blue dye and red light: a dynamic combination for prophylaxis and treatment of cutaneous Candida albicans infections in mice. Antimicrob Agents Chemother. 2011 Dec;55(12):5710-7.
Dai T, Kharkwal GB, Zhao J, Denis TG, Wu Q, Xia Y, Huang L, Sharma SK, d'Enfert C, Hamblin MR. Ultraviolet-C Light for Treatment of Candida albicans Burn Infection in Mice. Photochem Photobiol. 2011 Jan 5.
Dai T, Tegos GP, St. Denis TG, Anderson D, Sinofsky E, Hamblin, MR. Ultraviolet-C Irradiation for Prevention of Central Venous Catheter Related Infections: An In-vitro Study. Photochem Photobiol. 2011 Jan-Feb;87(1):250-5. Epub 2010 Nov 12.
Dai T, Tanaka M, Huang YY, Hamblin MR. Chitosan preparations for wounds and burns: antimicrobial and wound healing effects. Expert Rev Anti-Infect Ther. 2011, 9(7):857-879.
Dai T, Kharkwal GB, Tanaka M, Huang YY, Bil de Arce VJ, Hamblin MR. Animal models of external traumatic wound infections. Virulence. 2011. 2:(4), 296-315.
Fiamegos YC, Kastritis PL, Exarchou V, Han H, Bonvin MJ, Vervoot J, Lewis K, Hamblin MR, Tegos GP. Antimicrobial and efflux pump inhibitory activity of caffeoylquinic acids from Artemisia absinthium against Gram-positive pathogenic bacteria. PLoS ONE, 2011, 6(4): e18127. PMC3070693
Garcez AS, Núñez SC, Baptista MS, Daghastanli NA, Itri R, Hamblin MR, Ribeiro MS. Antimicrobial mechanisms behind photodynamic effect in the presence of hydrogen peroxide. Photochem Photobiol Sci. 2011 Apr 30;10(4):483-90. Epub 2010 Dec 2.
Hamblin MR. Reply to "Championing Photoantimicrobial Discovery". Photodiagn Photodyn Ther. 2011.
Huang L, Dai T, Xuan Y, Tegos GP, Hamblin MR. Synergistic combination of chitosan acetate with nanoparticle silver as a topical antimicrobial: efficacy against bacterial burn infections. Antimicrob Agents Chemother. 2011, Jul;55(7):3432-8. Featured in http://www.mdlinx.com/nurse-practitioner/news-article.cfm/3646304. PMCID: PMC3122390
Huang L, Zhiyentayev T, Xuan Y, Azhibek D, Kharkwal GB, Hamblin MR. Photodynamic inactivation of bacteria using polyethylenimine-chlorin(e6) conjugates: Effect of polymer molecular weight, substitution ratio of chlorin(e6) and pH. Lasers Surg Med. 2011 Apr;43(4):313-23.
Kharkwal GB, Sharma SK, Huang YY, Dai T, Hamblin MR. Photodynamic Therapy for Infections: Clinical Applications. Lasers Surg Med, 2011 43:755-767.
Mizuno K, Zhiyentayev T, Huang L, Khalil1 S, Nasim F, Tegos GP, Gali H, Jahnke A, Wharton T, Hamblin MR. Antimicrobial photodynamic therapy with functionalized fullerenes: Quantitative structure-activity relationships. J Nanomedic Nanotechnol 2011, 2:2
Mroz P, Hamblin MR. The immunosuppressive side of PDT. Photochem Photobiol Sci. 2011 May 1;10(5):751-8.
Mroz P, Xia Y, Asanuma D, Konopko A, Zhiyentayev T, Huang YY, Sharma SK, Dai T, Khan UJ, Wharton T, Hamblin MR. Intraperitoneal photodynamic therapy mediated by a fullerene in a mouse model of abdominal dissemination of colon adenocarcinoma. Nanomedicine. 2011 Dec;7(6):965-74.
Mroz P, Hashmi JT, Huang YY, Lange N, Hamblin MR. Stimulation of anti-tumor immunity by photodynamic therapy. Expert Rev Clin Immunol. 2011 Jan;7(1):75-91.
Mroz P, Yaroslavsky A, Kharkwal GB Hamblin MR. Cell Death Pathways in Photodynamic Therapy of Cancer. Cancers 2011. 3, 2516-2539.
Naeser MA, Hamblin MR. Potential for Transcranial Laser or LED Therapy to Treat Stroke, Traumatic Brain Injury, and Neurodegenerative Disease. Photomed Laser Surg. 2011, 29(7); 443-446.
Naeser MA, Saltmarche A, Krengel MH, Hamblin MR, Knight JA. Improved Cognitive Function After Transcranial, Light-Emitting Diode Treatments in Chronic, Traumatic Brain Injury: Two Case Reports. Photomed Laser Surg. 2011. May;29(5):351-8. Reviewed in http://topnews.us/content/237119-transcranial-light-therapy-may-help-tbi-patients.
Prates RA, Kato IT, Ribeiro MS, Tegos GP, Hamblin MR. Influence of multidrug efflux systems on methylene blue-mediated photodynamic inactivation of Candida albicans. J Antimicrob Chemother. 2011 Jul;66(7):1525-32.
Sharma SK, Dai T, Kharkwal GB, Huang YY, Huang L, De Arce VJ, Tegos GP, Hamblin MR. Drug Discovery of Antimicrobial Photosensitizers using Animal Models. Curr Pharm Des. 2011 Apr 20. [Epub ahead of print]
Sharma SK, Chiang LY, Hamblin MR. Photodynamic therapy with fullerenes in vivo: reality or a dream? Nanomedicine (Lond). 2011 Dec;6(10):1813-25.
Sharma SK, Kharkwal GB, Sajo M, Huang YY, De Taboada L, McCarthy T, Hamblin MR. Dose response effects of 810-nm laser-light on mouse primary cortical neurons. Lasers Surg Med. 2011 Sep;43(8):851-9.
St Denis TG, Huang L, Dai T, Hamblin MR. Analysis of the Bacterial Heat Shock Response to Photodynamic Therapy-mediated Oxidative Stress. Photochem Photobiol. 2011 2011 May-Jun;87(3):707-13.
St Denis TG, Aziz K, Waheed AA, Huang YY, Sharma SK, Mroz P, Hamblin MR. Combination approaches to potentiate immune response after photodynamic therapy for cancer. Photochem Photobiol Sci, 2011 May 1;10(5):792-801.
St Denis TG, Dai T, Izikson A, Astrakas C, Anderson RR, Hamblin MR, Tegos GP. All you need is light. Antimicrobial photoinactivation as an evolving and emerging discovery strategy against infectious disease. Virulence. 2011 Nov 1;2(6):509-20. Epub 2011 Nov 1.
Tanaka M, Kinoshita M, Yoshihara Y, Shinomiya N, Seki S, Nemoto K, Hamblin MR, Morimoto Y. Photodynamic therapy using intra-articular photofrin for murine MRSA arthritis: Biphasic light dose response for neutrophil-mediated antibacterial effect. Lasers Surg Med. 2011 Mar;43(3):221-9.
Wainwright M, Dai T, Hamblin MR. Antimicrobial photodynamic therapy in the colon: delivering a light punch to the guts? Photochem Photobiol. 2011 Jul-Aug;87(4):754-6.
2010
Chen Z, Zhou S, Chen J, Deng Y, Luo Z, Chen H, Hamblin MR, Huang M. Pentalysine b-Carbonylphthalocyanine Zinc: An Effective Tumor-Targeting Photosensitizer for Photodynamic Therapy. ChemMedChem, 2010 Jun 7;5(6):890-8.
Chiang LY, Padmawar PA, Rogers-Haley JE, So G, Canteenwala T, Thota S, Tan LS, Pritzker K, Huang YY, Sharma SK, Kurup DB, Hamblin, MR. Wilson BC, Urbas A. Synthesis and characterization of highly photoresponsive fullerenyl dyads with a close chromophore antenna–C60 contact and effective photodynamic potential. J Mater Chem. 2010 Jan 1;20(25):5280-5293.
Coleman JJ, Okoli I, Tegos GP, Holson E, Wagner FF, Hamblin MR, Mylonakis E. Characterization of plant-derived saponin natural products against Candida albicans. ACS Chem Biol, 2010 Mar 19;5(3):321-32. Epub ahead of print
Dai T, Huang YY, Sharma SK, Hashmi JT, Kurup DB Hamblin MR. Topical Antimicrobials for Burn Wound Infections. Recent Patents on Anti-Infective Drug Discovery, 2010 Jun 1;5(2):124-51.
Dai T, Tegos GP, Zhiyentayev T, Mylonakis E, Hamblin MR. Photodynamic Therapy for Methicillin-Resistant Staphylococcus aureus Infection in a Mouse Skin Abrasion Model. Lasers Surg Med; 2010, 42: 38-44.
Garcez SG, Núñez SC, Baptista MS, Daghastanli NA, Itri R, Hamblin MR, Ribeiro MS. Antimicrobial mechanisms behind photodynamic effect in the presence of hydrogen peroxide. Photochem Photobiol Sci. 2010 Dec 2. [Epub ahead of print]
Garcez AS, Nunez SC, Hamblin MR, Suzuki H, Ribeiro MS. Photodynamic therapy associated with conventional endodontic treatment in patients with antibiotic resistant microflora. A preliminary report. J Endod. 2010; 36(9): 1463-1466.
Hamblin, MR. Introduction to Experimental and Clinical Studies Using Low-Level Laser (Light) Therapy (LLLT). Lasers Surg Med. 2010 Aug;42(6):447-9.
Hamblin MR, Dai T. Can surgical site infections be treated by photodynamic therapy? Photodiagnosis Photodyn Ther. 2010 Jun;7(2):134-6.
Hashmi JT, Huang Y-Y, Sharma SK, Kurup DB, De Taboada L, Carroll JD, Hamblin MR. Effect of pulsing in low-level light therapy. Laser Surg Med, 2010, 42:450-466.
Hashmi JT, Huang YY, Osmani BZ, Sharma SK, Naeser MA, Hamblin MR. Role of Low-Level Laser Therapy in Neurorehabilitation. Physical Medicine and Rehabilitation 2010;2:S292-S305.
Huang L, Dai T, Hamblin MR. Antimicrobial photodynamic inactivation and photodynamic therapy for infections. Methods Mol Biol. 2010;635:155-73.
Huang L, Terakawa M, Zhiyentayev T, Huang YY, Sawayama Y, Jahnke A, Tegos GP, Wharton T, Hamblin MR. Innovative cationic fullerenes as broad-spectrum light-activated antimicrobials. Nanomedicine. 2010 Jun;6(3):442-52. Epub 2009 Nov 12.
Huang L, Huang YY, Mroz P, Tegos GP, Zhiyentayev T, Sharma SK, Lu Z, Balasubramanian T, Krayer M, Ruzié C, Yang E, Kee HL, Kirmaier C, Diers JR, Bocian DF, Holten D, Lindsey JS, Hamblin MR. Stable Synthetic Cationic Bacteriochlorins As Selective Antimicrobial Photosensitizers. Antimicrob Agents Chemother, 2010, 54; 3834-3841.
Huang YY, Mroz P, Zhiyentayev T, Sharma SK, Balasubramanian T, Ruzié C, Borbas KE, Fan D, Krayer M, Yang E, Kee HL, Kirmaier C, Diers JR, Bocian DF, Holten D, Lindsey JS, Hamblin MR. In Vitro Photodynamic Therapy and Quantitative Structure-Activity Relationship Studies with Stable Synthetic Near-Infrared-Absorbing Bacteriochlorin Photosensitizers. J Med Chem, 2010 May 27;53(10):4018-27.
Kishen A, Upadya M, Tegos GP, Hamblin MR. Efflux Pump Inhibitor Potentiates Antimicrobial Photodynamic Inactivation of Enterococcus faecalis Biofilm. Photochem Photobiol 2010 Nov-Dec;86(6):1343-9.
Lu Z, Dai T, Huang L, Kurup DB, Tegos GP, Jahnke A, Wharton T, Hamblin, MR. Photodynamic therapy with a cationic functionalized fullerene rescues mice from fatal wound infections. Nanomedicine (Lond). 2010 Dec;5(10):1525-33.
Mroz P, Huang YY, Szokalska A, Zhiyentayev T, Janjua S, Nifli AP,. Sherwood ME, Ruzié C, Borbas KE, Fan D, Krayer M, Balasubramanian T, Yang E, Kee HL, Kirmaier C, Diers JR, Bocian DF, Holten D, Lindsey JS, Hamblin MR. Stable synthetic bacteriochlorins overcome the resistance of melanoma to photodynamic therapy. FASEB J. 2010 Sep;24(9):3160-70. Epub 2010 Apr 12.
Mroz P, Szokalska A, Wu MX, Hamblin MR. Photodynamic Therapy of Tumors Can Lead to Development of Systemic Antigen-Specific Immune Response. PLoS ONE 2010, 5(12): e15194.
Naeser MA, Saltmarche A, Krengel MH, Hamblin MR, Knight JA. Improved Cognitive Function After Transcranial, Light-Emitting Diode Treatments in Chronic, Traumatic Brain Injury: Two Case Reports. Photomed Laser Surg. 2010 Dec 23. [Epub ahead of print]
Park J, Mroz P, Salomatina E, Hamblin MR, Yaroslavsky AN. Dye-enhanced multimodal confocal microscopy for noninvasive detection of skin cancers in mouse models. J Biomed Optics, 2010, 15(2), 026023
Ragas X, Dai T, Tegos GP, Agut M, Nonell S, Hamblin MR. Photodynamic inactivation of Acinetobacter baumannii using phenothiazinium dyes: in-vitro and in-vivo studies. Lasers Surg Med; 2010 Jul;42(5):384-90.
Ragàs X, Sánchez-García D, Ruiz-Gonzalez R, Dai T, Agut M, Hamblin MR, Nonell S. Cationic Porphycenes as Potential Photosensitizers for Antimicrobial Photodynamic Therapy. J Med Chem 2010 Nov 11;53(21):7796-803.
2009
Dai T, Huang YY, Hamblin MR. Photodynamic therapy for localized infections--state of the art. Photodiagnosis Photodyn Ther. 2009 Sep-Dec;6(3-4):170-88.
Dai T, Tegos GP, Lu Z, Huang L, Zhiyentayev T, Franklin MJ, Baer DG, Hamblin MR. Photodynamic therapy for Acinetobacter baumannii burn infections in mice. Antimicrob. Agents Chemother. 2009 53: 3929-3934
Dai T, Tegos GP, Burkatovskaya M, Castano AP, Hamblin MR. Chitosan acetate bandage as a topical antimicrobial dressing for infected burns. Antimicrob Agents Chemother 2009 Feb;53(2):393-400. Epub 2008 Nov 17.
George S, Hamblin MR, Kishen A. Uptake pathways of anionic and cationic photosensitizers into bacteria. Photochem Photobiol Sci 2009. 8, 788-795.
Huang Y-Y, Chen A C-H, Carroll JD. Hamblin MR. Biphasic dose response in low-level light therapy. Dose Response, 2009, 7, 358-383.
Lembo AJ, Ganz RA , Sheth S, Cave D, Kelly C, Levin P, Kazlas PT, Baldwin PC III, Lindmark WR, McGrath JR, Hamblin MR. Treatment of Helicobacter pylori Infection with Intra-Gastric Violet Light Phototherapy - a Pilot Clinical Trial. Lasers Surg Med. 2009. 41(5):337-344.
Mroz P, Bhaumik J, Dogutan DK, Aly Z, Kamal Z, Khalid J, Kee HK, Bocian DF, Holten D, Lindsey JS and Hamblin MR. Imidazole metalloporphyrins as photosensitizers for photodynamic therapy: Role of molecular charge, central metal and hydroxyl radical production. Cancer Lett 2009, 282:63-76.
Schiffer F, Johnston AL. Polcari A, Teicher MH, Webb RH, Hamblin MR. Psychological benefits 2 and 4 weeks after a single treatment with near infrared light to the forehead: A pilot study of 10 patients with major depression and anxiety. Behavioral Brain Res. 2009, 5, 46-55.
Szokalska A, Makowski M, Nowis D, Wilczynski GM, Kujawa M, Wójcik C, Mlynarczuk-Bialy I, Salwa P, Bil J, Janowska S, Agostinis P, Verfaillie T, Bugajski M, Gietka J, Issat T, Glodkowska E, Mrówka P, Stoklosa T, Hamblin MR , Mróz P, Jakóbisiak M, Golab J. Proteasome inhibition potentiates antitumor effects of photodynamic therapy in mice through induction of ER stress and unfolded protein response. Cancer Res. 2009. 69(10):4235-43.
2008
Burkatovskaya M, Castaño AP, Demidova-Rice T Tegos GP, Hamblin MR. Effect of chitosan acetate bandage on wound healing in infected and noninfected wounds in mice. Wound Rep Reg 2008;16:425-431.
Castaño AP, Mroz P, Wu MX, Hamblin MR. Photodynamic therapy plus low-dose cyclophosphamide generates antitumor immunity in a mouse model. Proc Natl Acad Sci U S A 2008 Apr 8;105(14):5495-500. Epub 2008 Mar 31.
Dai T, Tegos GP, Rolz-Cruz G, Cumbie WE, Hamblin MR. Ultraviolet C inactivation of dermatophytes: implications for treatment of onychomycosis. Brit J Dermatol 2008;158:1239-1246.
Garcez, AS, Nunez SC, Hamblin MR, and Ribeiro MS. Antimicrobial effects of photodynamic therapy on patients with necrotic pulps and periapical lesion. J Endodont 2008, 34:138-142.
Kee HL, Bhaumik J, Diers JR, Mroz P, Hamblin MR, Bocian DF, Lindsey JS, Holten D. Photophysical characterization of imidazolium-substituted Pd(II), In(III), and Zn(II) porphyrins as photosensitizers for photodynamic therapy. J Photochem Photobiol A 2008;200:346-355.
Tawakol A, Castano AP, Gad F, Zahra T, Bashian G, Migrino RQ, Ahmadi A, Stern J, Anatelli F, Chirico S, Shirazi A, Syed S, Fischman AJ, Muller JE, and Hamblin MR. Intravascular detection of inflamed atherosclerotic plaques with a scavenger receptor-targeted fluorescent photosensitizer. Photochem Photobiol Sci 2008, 7, 33-39.
Tegos GP, Masago K, Aziz F, Higginbotham A, Stermitz FR, Hamblin MR. Inhibitors of bacterial multidrug efflux pumps potentiate antimicrobial photoinactivation. Antimicrob Agents Chemother 2008 May 12; [Epub ahead of print]
Wang XL, Wang HW, Hillemanns P, Hamblin MR. Distinctive features of foreskin condylomata acuminata associated with diabetes mellitus. Acta Derm Venereol 2008;88(6):578-83.
[Return to top]2007
Apidianakis Y, Mindrinos MN, Xiao W, Tegos GP, Papisov MI, Hamblin MR, Davis RW, Tompkins RG, and Rahme LG. Involvement of skeletal muscle gene regulatory network in susceptibility to wound infection following trauma. PLoS ONE 2007;2:e1356-1365.
Castano AP, Dai T, Yaroslavsky I, Cohen R, Apruzzese AW, Smotrich MH, Hamblin MR. Low-level laser therapy for zymosan-induced arthritis in rats: Importance of illumination time. Lasers Surg Med 2007;39(6):543-550.
Demidova-Rice TN, Salomatina EV, Yaroslavsky AN, Herman IM, Hamblin MR. Low-level light stimulates excisional wound healing in mice. Lasers Surg Med 2007;39(9):706-715.
Fuchs, BB, Tegos GP, Hamblin MR, and Mylonakis E. Susceptibility of Cryptococcus neoformans to photodynamic inactivation Is associated with cell wall integrity. Antimicrob Agents Chemother 2007;51(8):2929-36.
Garcez AS, Nunez SC, Lage-Marques JL, Hamblin MR, Ribeiro MS. Photonic real-time monitoring of bacterial reduction in root canals by genetically engineered bacteria after chemomechanical endodontic therapy. Braz Dent J 2007;18(3):202-7.
Garcez, AS; Ribeiro MS, Tegos GP, Nunez SC, Jorge AO, Hamblin MR. Antimicrobial photodynamic therapy combined with conventional endodontic treatment to combat root canal infection. Lasers Surg Med 2007;39(1):59-66.
Moller-Kristensen M, Hamblin MR, Thiel S, Jensenius JC, Takahashi K. Burn Injury reveals altered phenotype in Mannan-Binding lectin-deficient mice. J Invest Dermatol 2007;127:1524-1531.
Mroz P, Pawlak A, Satti M, Lee H, Wharton T, Gali H, Sarna T and Hamblin MR. Functionalized fullerenes mediate photodynamic killing of cancer cells: Type I versus Type II photochemical mechanism. Free Radical Biol Med 2007;43(5):711-9.
Mroz P, Tegos GP, Gali H, Wharton T, Sarna T, Hamblin MR. Photodynamic therapy with fullerenes. Photochem Photobiol Sci 2007;6:1139-1149.
Tang HM, Hamblin MR, Yow, CM. A comparative in vitro photoinactivation study of clinical isolates of multidrug-resistant pathogens. J Infect Chemother 2007;13(2):87-91.
[Return to top]2006
Anatelli F, Mroz P, Liu Q, Yang C, Castano AP, Swietlik E, Hamblin MR. Macrophage-targeted photosensitizer conjugate delivered by intratumoral injection. Mol Pharm 2006;3(6):654-664.
Borbas KE, Mroz P, Hamblin MR, and Lindsey JS. Bioconjugatable porphyrins bearing a compact swallowtail motif for water solubility. Bioconj Chem 2006;17:638-653.
Burkatovskaya M, Tegos GP, Swietlik E, Demidova TN, P Castano A, Hamblin MR. Use of chitosan bandage to prevent fatal infections developing from highly contaminated wounds in mice. Biomaterials 2006;27(22):4157-4164.
Castaño AP, Liu Q, and Hamblin MR. Green fluorescent protein expressing but not wild-type tumors in mice are cured by photodynamic therapy. Brit J Cancer 2006;94:391-397.
Castaño AP, Mroz P, and Hamblin MR. Photodynamic therapy and anti-tumour immunity. Nat Rev Cancer 2006;6:535-545.
Foley JW, Song X, Demidova TN, Jilal F, Hamblin MR. Synthesis and properties of benzo[a]phenoxazinium chalcogen analogs as novel broad-spectrum antimicrobial photosensitizers. J Med Chem 2006;49:5291-5299.
Møller-Kristensen M, Shi L, Ip E, Gowda LD, Hamblin MR, Thiel S, Jensenius JC, Ezekowitz RA, Takahashi K. Deficiency of mannose-binding lectin greatly increases susceptibility to post-burn infection with Pseudomonas aeruginosa. J Immunol 2006;176(3):1769-1775.
Tawakol A, Castano AP, Anatelli F, Bashian G, Stern J, Zahra T, Gad F, Chirico S, Ahmadi A, Fischman AJ, Muller JE, Hamblin MR. Photosensitizer delivery to vulnerable atherosclerotic plaque: comparison of macrophage-targeted conjugate versus free chlorin(e6). J Biomed Optics 2006;11:210-218.
Tegos GP, Hamblin MR. Phenothiazinium antimicrobial photosensitizers are substrates of bacterial multidrug resistance pumps. Antimicrob Agents Chemother 2006;50:196-203.
Tegos GP, Anbe M, Yang C, Demidova TN, Satti M, Mroz P, Janjua S, Gad F and Hamblin MR. Protease stable polycationic photosensitizer conjugates between polyethyleneimine and chlorin(e6) for broad spectrum antimicrobial photoinactivation. Antimicrob Agents Chemother 2006;50:1402-1410.
[Return to top]2005
Castaño AP, Demidova TN, Hamblin MR. Mechanisms in photodynamic therapy: part two - cellular signaling, cell metabolism and modes of cell death. PPT 2005;2:1-23.
Castaño AP, Demidova TN, Hamblin MR. Mechanisms in photodynamic therapy: part three - Photosensitizer pharmacokinetics, biodistribution, tumor localization and modes of tumor destruction. PPT 2005;2:91-106.
Demidova TN, Hamblin MR. Effect of cell-photosensitizer binding & cell density on microbial photoinactivation. Antimicrob Agents Chemother 2005;49(6):2329-35.
Demidova TN, Gad F, Zahra T, Francis KP, Hamblin MR. Monitoring photodynamic therapy of localized infections by bioluminescence imaging of genetically engineered bacteria. J Photochem Photobiol B 2005;81:15-25.
Demidova TN, Hamblin MR. Photodynamic inactivation of Bacillus spores, mediated by phenothiazinium dyes. Appl Environ Microb 2005;71(11):6918-25.
Ganz RA, Viveiros J, Ahmad A, Ahmadi A, Khalil A, Tolkoff MJ, Nishioka NS, Hamblin MR. Helicobacter pylori in patients can be killed by visible light. Laser Surg Med 2005;36(4):260-5.
Hamblin MR, Viveiros J, Yang C, Ahmadi A, Ganz RA, Tolkoff MJ. Heliobacter pylori accumulates photoactive porphyrins and is killed by visible light. Antimicrob Agents Chemother 2005;49(7):2822-7.
Lambrechts SA, Demidova TN, Aalders MC, Hasan T, Hamblin MR. Phtodynamic therapy for Staphylococcus aureus infected burn wounds in mice. Photochem Photobiol 2005;4:503-9.
Liu Q, Hamblin MR. Macrophage-targeted photodynamic therapy: scavenger receptor expression and activation state. Int J Immunopath Pharmacol 2005;18:391-402.
Tegos GP, Demidova TN, Arcilla-Lopez D, Wharton T, Hariprased G, Hamblin MR. Cationic fullerenes are effective and selective antimicrobial photosensitizers. Chem Biol 2005;12:1127-35.
[Return to top]2004
Castaño AP, Demidova TN, Hamblin MR. Mechanisms in photodynamic therapy: part one - photosensitizers, photochemistry and cellular localization. Photodiag Photo Ther 2004;1:279-93.
Demidova TN, Hamblin MR. Macrophage-targeted photodynamic therapy. Int J Immunopathol Pharmacol 2004;17(2):117-26.
Demidova TN, Hamblin MR. Photodynamic therapy targeted to pathogens. Int J Immunopathol Pharmacol 2004;17(3):245-54.
Gad F, Zahra T, Hasan T, Hamblin MR. Effects of growth phase and extracellular slime on photodynamic inactivation of gram-positive pathogenic bacteria. Antimicrob Agents Chemother 2004;48(6):2173-8.
Gad F, Zahra T, Francis K, Hasan T, Hamblin MR. Targeted photodynamic therapy of established soft-tissue infections in mice. Photochem Photobiol Sci 2004;3(5):451-458.
Hamblin MR, Hasan T. Photodynamic therapy: a new antimicrobial approach to infectious disease? Photochem Photobiol Sci 2004;3(5):436-50.
Khadem JJ, Martino M, Anatelli F, Dana MR, Hamblin MR. Healing of perforating rat corneal incisions closed with photodynamic laser-activated tissue glue. Lasers Surg Med 2004;35(4):304-11.
Shi L, Takahashi K, Dundee J, Shahroor-Karni S, Thiel S, Jensenius JC, Gad F, Hamblin MR, Sastry KN, Ezekowitz RAB. Mannose-binding lectin-deficient mice are susceptible to infection with staphylococcus aureus. J Exp Med 2004;199(10):1379-90.
[Return to top]2003
Hamblin MR, Miller JL, Rizvi I, Loew HG, Hasan T. Pegylation of charged polymer-photosensitizer conjugates: effects on photodynamic efficacy. Br J Cancer 2003; 89:937-943.
Hamblin MR, Zahra T, Contag CH, McManus AT, Hasan T. Optical monitoring and treatment of potentially lethal wound infections in-vivo. J Infect Dis 2003; 187:1717-1725.
Kodama T, Doukas AG, Hamblin MR. Delivery of ribosome-inactivating protein toxin into cancer cells with shock waves. Cancer Lett 2003; 189:69-75.
[Return to top]2002
Hamblin MR, O'Donnell DA, Murthy N, Contag CH, Hasan T. Rapid control of wound infections by targeted photodynamic therapy monitored by In-vivo bioluminescence imaging. Photochem Photobiol 2002; 75(1):51-57.
Hamblin MR, O'Donnell DA, Murthy N, Rajagopalan K, Michaud N, Sherwood ME, Hasan T. Polycationic photosensitizer conjugates: effects of chain length and Gram classification on the photodynamic inactivation of bacteria. J Antimicrob Chemoth 2002; 49:941-951.
Hamblin MR, Miller JL, Rizvi I, Ortel B. Degree of substitution of chlorin(e6) conjugated to charged poly-L-lysine chains affects their cellular uptake, localization and phototoxicity towards macrophages and cancer cells. J X-ray Sci Tech May 2002; 10:139-152.
Hamblin MR. Covalent photosensitizer conjugates for targeted photodynamic therapy. Trends in Photochem Photobiol 2002; 9:1-24.
Kodama T, Doukas AG, Hamblin MR. Shock wave-mediated molecular delivery into cells. Biochem Biophys Acta 2002; 1542:186-194.
[Return to top]2001
Hamblin MR, Miller JL, Rizvi I, Ortel B, Maytin EV, Hasan T. Pegylation of a chlorine6 polymer conjugate increases tumor targeting of photosensitizer. Cancer Res 2001; 61:7155-7162.
Soukos NS, Hamblin MR, Keel S, Fabian RL, Deutsch TF, Hasan T. Epidermal growth factor receptor-targeted immunophotodiagnosis and photoimmunotherapy of oral precancer in-vivo. Cancer Res 2001; 61:4490-4496.
[Return to top]2000
Del Governatore M, Hamblin MR, Piccinini EE, Ugolini G, Hasan T. Targeted photodestruction of human colon cancer cells using charged 17.1a chlorine6 immunoconjugates. Br J Cancer 2000; 82:56-64.
Del Governatore M, Hamblin MR, Shea CR, Rizvi I, Molpus KL, Tanabe KK, Hasan T. Experimental photoimmunotherapy of hepatic metastases of colorectal cancer with a 17.1A chlorine6 immunoconjugate. Cancer Res 2000; 60:4200-4205.
Hamblin MR, Miller JL, Ortel B. Scavenger-receptor targeted photodynamic therapy. Photochem Photobiol 2000; 72:533-540.
Hamblin MR, Del Governatore M, Rizvi I, Hasan T. Biodistribution of charged 17.1A photoimmunoconjugates in a murine model of hepatic metastasis of colorectal cancer. Br J Cancer 2000; 83:1544-1551.
Kodama T, Hamblin MR, Doukas AG. Cytoplasmic molecular delivery with shock waves: importance of impulse. Biophys J 2000; 79:1821-1832.
Molpus KL, Hamblin MR, Rizvi I, Hasan T. Intraperitoneal photoimmunotherapy of ovarian carcinoma xenografts in nude mice using charged photoimmunoconjugates. Gynecol Oncol 2000; 76:397-404.
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