Summer group 2012: Oliver Klein, SungYoon Kim, Yookyung Jung, Sarah Rae Rokosh, Alex Nichols, Nicole DeVoe, Amanda Johnson, Manolis Rousakis, Conor Evans


     
 
Lachlan Hanbury-Brown
Undergraduate Student

     
 
Hsin-I (Cindy) Hung, PhD
Research Fellow
My research is on applying oxygen independent photosensitizers with photodynamic therapy (PDT) to improve cancer therapy efficacy in the hypoxia-driven resistant cancers. Simultaneously, utilize non-invasive imaging system for early cancer detection and monitoring treatment outcome by using oxygen detection probe as a diagnostic and quantitative measurement to monitor disease progress and in vivo treatment response in metastatic ovarian cancer model.
     
 
Yookyung Jung, PhD
Research Fellow
My research interest is developing novel optical imaging methods and applying them to biological imaging. Current research focuses are nerve imaging by coherent anti-Stokes Raman scattering (CARS) microscopy and tissue clearing. I am additionally working to visualize the treatment response of 3D in vitro tumor models using optical coherence tomography (OCT) and segmentation analysis routines.
     
 
Oliver Klein
Research Technician II
Oliver J. Klein's research focus is in the development of multi-tiered, imaging-based screening platforms utilizing in vitro 3D tumor models of treatment-resistant disease for the development and optimization of photodynamic therapy agents as well as to correlate tumor microenvironmental factors such as hypoxia and acidosis with poor treatment response in patients with resistant metastatic epithelial ovarian cancer.
     
 
Zongxi Li, PhD
Research Fellow
One of my projects is oxygen photography, creating a custom camera system that works with a clear bandage in a minimally interactive fashion to provide tissue oxygenation states. The product allows physicians to easily assess skin perfusion level to prevent flap surgery failure, and helps predicting wound healing probability. I am also working to develop a fiber-optic guided microendoscope for the in-vivo visualization of ovarian tumor nodules and to perform tumor hypoxia imaging in mice models.
     
 
Alexander Nichols
Graduate Student
I am a PhD student jointly enrolled in the Harvard University Program in Biophysics and the Harvard/MIT Division of Health Sciences and Technology (HST). My research interests include development of methodologies for making oxygen measurements in avascular tumors and single cells, synthesis of novel optical probes, development of intravital imaging and cell-tracking techniques, and construction of new optical imaging tools.
     
 
Joachim Pruessner
Graduate Student

     
 
Emmanouil Rousakis, PhD
Research Fellow
My current research focuses on the development of brightly phosphorescent, oxygen-sensitive probes for imaging tissue perfusion and oxygenation status non-invasively, as well as the development of cell-permeable analogues for visualizing hypoxia and monitoring treatment response in vitro in complex tumor models.
     
 
Benjamen Sun
Graduate Student

     
 
Jeffrey Wang
Undergraduate Student





Previous team members


Undergraduate Students

Name   Role in Lab   Dates   Where now
Amanda Johnson HST Summer Student 2012 Sweet Briar College
             
SungYoon Kim   KAIST-Wellman Summer Student   2012   Korea Advanced Institute of Science and Technology (KAIST)
             
Matthew Patton   Harvard PRISE Student   2011   Harvard University
             
Yong Jin Park   KAIST-Wellman Summer Student   2010   Graduate Student, MIT Biological Engineering
             
Sam Peterson   Undergraduate Research Assistant   2011-2012   Harvard University
             
Sarah Rae Rokosh   New York University Medical School   2011
2012
  McGill University


Graduate Students

Name   Role in Lab   Dates   Where now
Rui Shi Visiting Graduate Student 2012-2013