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Michael R. Jaff, D.O.
Professor of Medicine, Harvard Medical School;
Medical Director, Vascular Diagnostic Laboratory
(617) 726-3784 p
(617) 724-0371 f

Clinical Background:
D.O. Kirksville College of Osteopathic Medicine, Kirksville, Missouri
Cleveland Clinic Foundation (Internal Medicine) 1986-1989
Cleveland Clinic Foundation (Chief Resident, Internal Medicine) 1989-1990
Cleveland Clinic Foundation (Vascular Medicine) 1991-1992
Board Certification:
Internal Medicine (1989)

Dr. Jaff was appointed Medical Director of the Vascular Diagnostic Laboratory in 2004. He is the director of the Vascular Ultrasound Core Laboratory, the largest clinical device research ultrasound laboratory in the World. The laboratory was founded in 1997, and has participated in over 35 clinical device trials.

Clinical Interests:
His interests include the non-invasive evaluation of patients with vascular diseases; carotid, renal, and lower extremity arterial diseases; venous thromboembolic disease; and novel pharmacotherapeutic strategies for vascular disease.

Dr. Jaff is particularly interested in the safety and durability of endovascular devices (predominantly stents) used as therapy for peripheral vascular diseases. He is also the current principal investigator for a therapeutic angiogenesis trial for the treatment of intermittent claudication.

Recent Publications:
Kent KC, Zwolak RM, Jaff MR, et al. Screening for abdominal aortic aneurysm: a consensus statement. J Vasc Surg 2004;39:267-9.

Haire WD, Deitcher SR, Mullane KM, Jaff MR, et al. Recombinant urokinase for restoration of patency in occluded central venous access devices: a double-blind, placebo controlled trial. Thromb Haemost. 2004 Sep;92(3):575-82.

Ponec D, Jaff MR, Swischuk J, et al. The Nitinol SMART stent vs. Wallstent for Suboptimal Iliac Artery Angioplasty: The CRISP-US Trial Results. J Vasc Interv Radiol. 2004 Sep;15(9):911-8.

Yadav JS, Wholey MH, Kuntz RE, Fayad P, Katzen BT, Mishkel GJ, Bajwa TK, Whitlow P, Strickman NE, Jaff MR, et al. Protected carotid artery stenting vs endarterectomy in high risk patients. N Engl J Med. 2004 Oct 7;351(15):1493-501.

Svoboda P, Barton RP, Barbarash OL, Butylin AA, Jacobs BR, Lata J, Haire WD, Jaff MR, Recombinant urokinase is safe and effective in restoring patency to occluded central venous access devices: a multicenter international trial. Critical Care Medicine 2004;32:1990-6.

Rosenfield K, Cowley MJ, Jaff MR. et al. SCAI/SVMB/SVS clinical competence statement on carotid stenting: training and credentialing for carotid stenting—multispecialty consensus recommendations, a report of the SCAI/SVMB/SVS writing committee to develop a clinical competence statement on carotid interventions. J Am Coll Cardiol 2005;45:165-74.


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