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Leigh R. Hochberg, M.D., Ph.D.

Leigh R. Hochberg, M.D., Ph.D.

Titles and Contact Information

Assistant in Neurology, Massachusetts General Hospital

Associate Neurologist, Brigham and Women's Hospital

Consulting Staff in Neurology, Spaulding Rehabilitation Hospital

Investigator, Rehabilitation R&D, Dept. Veterans Affairs

Visiting Associate Professor of Neurology, Harvard Medical School

Associate Professor of Engineering, Brown University

Appointments: (617) 726-4218

Affiliations and Profiles

Clinical Interests

  • Stroke
  • Neurocritical Care

Current Projects

BrainGate Clinical Trials

Clinical Background

1999 M.D. Degree Emory University School of Medicine
2003 Ph.D. Degree Emory University Neuroscience
2003 Residency Massachusetts General Hospital / Brigham and Women's Hospital
Neurology
2004 Fellowship Massachusetts General Hospital / Brigham and Women's Hospital
Stroke and NeuroCritical Care
2005 Board Certification Neurology

Articles

Nurmikko AV, Donoghue JP, Hochberg LR, Patterson WR, Song YK, Bull CW, Borton DA, Laiwalla F, Park S, Ming Y, Aceros J
Listening to Brain Microcircuits for Interfacing With External World—Progress in Wireless Implantable Microelectronic Neuroengineering Devices.
Proc IEEE.98:3.375-388.. ; ():

Truccolo W, Hochberg LR, Donoghue JP
Collective dynamics in human and monkey sensorimotor cortex: predicting single neuron spikes.
Nat Neurosci. 2010 Jan ; 13 (1): 105-11

Kim SP, Simeral JD, Hochberg LR, Donoghue JP, Black MJ
Neural control of computer cursor velocity by decoding motor cortical spiking activity in humans with tetraplegia.
J Neural Eng. 2008 Dec ; 5 (4): 455-76

Hochberg LR
Turning thought into action.
N Engl J Med. 2008 Sep 11; 359 (11): 1175-7

Truccolo W, Friehs GM, Donoghue JP, Hochberg LR
Primary motor cortex tuning to intended movement kinematics in humans with tetraplegia.
J Neurosci. 2008 Jan 30; 28 (5): 1163-78

Kim SP, Simeral JD, Hochberg LR, Donoghue JP, Friehs GM, Black MJ
Multi-state decoding of point-and-click control signals from motor cortical activity in a human with tetraplegia.
3rd International IEEE-EMBS Conference 2007 May:486-489. ; ():

Donoghue JP, Hochberg LR, Nurmikko AV, Black MJ, Simeral JD, Friehs G
Neuromotor prosthesis development.
Med Health R I. 2007 Jan ; 90 (1): 12-5

Hochberg LR, Taylor DM
Intuitive prosthetic limb control.
Lancet. 2007 Feb 3; 369 (9559): 345-6

Donoghue JP, Nurmikko A, Black M, Hochberg LR
Assistive technology and robotic control using motor cortex ensemble-based neural interface systems in humans with tetraplegia.
J Physiol. 2007 Mar 15; 579 (Pt 3): 603-11

Hochberg LR, Donoghue JP
Sensors for brain-computer interfaces.
IEEE Eng Med Biol Mag. ; 25 (5): 32-8

Aaron RK, Herr HM, Ciombor DM, Hochberg LR, Donoghue JP, Briant CL, Morgan JR, Ehrlich MG
Horizons in prosthesis development for the restoration of limb function.
J Am Acad Orthop Surg. 2006 Oct ; 14 (10 Suppl): S198-204

Hochberg LR, Serruya MD, Friehs GM, Mukand JA, Saleh M, Caplan AH, Branner A, Chen D, Penn RD, Donoghue JP
Neuronal ensemble control of prosthetic devices by a human with tetraplegia.
Nature. 2006 Jul 13; 442 (7099): 164-71

Kübler A, Mushahwar VK, Hochberg LR, Donoghue JP
BCI Meeting 2005--workshop on clinical issues and applications.
IEEE Trans Neural Syst Rehabil Eng. 2006 Jun ; 14 (2): 131-4

Hochberg LR, Sims JR, Davis BT
West Nile encephalitis in Massachusetts.
N Engl J Med. 2002 Mar 28; 346 (13): 1030-1

Burrow M, Dugger J, Humphrey DR, Reed DJ, Hochberg LR
Cortical control of a robot using a time-delay neural network.
International Conference on Rehabilitation Robotics, 1997. ; ():

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In the News

The MGH Neurology Department placed 3rd in US News Neurology / NeuroSurgery rankings for 2010.

Educational Video

Still from the Stroke Evaluation simulation

This video simulation of an Emergency stroke evaluation illustrates the care of patients with acute stroke by the MGH Acute Stroke team.