This study investigates whether low-dose testosterone replacement therapy will improve bone density, mood, sex drive, well-being, and amounts of body fat and muscle in women with hypopituitarism. Women with a history of pituitary problems are at an increased risk for bone loss, obesity, diminished libido, and a decreased quality of life. Testosterone is a natural hormone made by the ovaries and adrenal glands in women; however, when the pituitary gland does not function normally, testosterone levels may be low. This year-long study evaluated bone density, body composition, cognitive function, well-being, and blood markers in women between the ages of 18 and 50 with a history of pituitary disease.