MASSACHUSETTS GENERAL HOSPITAL
Department of Pharmacy
Department of Nursing
Critical Care
Generic Name: |
Morphine |
Trade Name: |
|
Action: |
Opiate Analgesic |
Indications: |
Analgesia, Chest Pain |
Administration Guidelines |
|
Usual Dosage Range and Route: |
SLOW IV INJECTION : 1 - 20mg over 4 to 5 minutes *LOADING DOSE IS USUALLY GIVEN PRIOR TO STARTING MAINTENANCE* MAINTENANCE : 1 - 150mg / hr TITRATED TO PATIENT'S RESPONSE |
Standard Concentration: |
1 mg / ml MICROINFUSION: |
EW Standard |
50mg/50ml (1mg/ml) |
Special Considerations: |
- Rapid injection can cause increased side effects - Tolerance may result in higher dosage requirements -When using a continuous infusion, a bowel regimen should be started to prevent an ileus or constipation. |
Precautions and Side Effects: |
- Respiratory depression, bradypnea - Bronchospasm, tachypnea - Ileus, constipation, nausea, vomiting - Hypotension - CNS depression - Tachy, bradycardia - Will potentiate other sedatives |
revised 04/08