MASSACHUSETTS GENERAL HOSPITAL
Department of Pharmacy
Department of Nursing
Critical Care
| Generic Name: | Metoprolol |
| Trade Name: | Lopressor |
| Action: | Beta Adrenergic Antagonist |
| Indications: | Hypertension Supraventricular tachycardia Angina pectoris Post myocardial infarction therapy in selected patients |
| Administration Guidelines: | |
| Usual Dosage Range and Route: |
LOAD: 5.0 mg IVP EVERY 2 MINUTES UP TO 15 mg MAINTENANCE: Oral therapy should be initiated as soon as possible as 25-50 mg orally every six to 12 hours titrated to patient tolerance |
| Special Considerations: | - PA-line monitoring of cardiac output,
cardiac index, PCWP, CVP, SVR, is encouraged during initiation of therapy in unstable
patients - Should be used with caution in patients with known history of bronchospasm OR chronic obstructive pulmonary disease |
| Precautions and Side Effects: | - Bradycardia, av block - Bronchospasm - Hypotension - Cardiac failure -CNS depression, hallucinations |
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