Generic Name:

Meperidine

Trade Name:

Demerol

Action:

Opiate Analgesic

Indications:

Analgesia
Sedation

Shivering

Administration Guidelines:

Usual Dosage Range and Route:

LOADING DOSE : 12.5 - 50 mg IVP over 2 - 5 minutes depending on patient requirement.

MAINTENANCE : May repeat every 2 - 3 hours as titrated to patient response.

Shivering: 12.5-100mg/hr titrated to patient response

Standard Concentrations

MICROINFUSION: 10mg/mL (30mL, 60mL)

Special Considerations:

- Rapid injection can cause increased incidence of side effects

- Drug tolerance may result in the need for higher dosage requirements

Precautions and Side Effects:

- Use caution in patients with renal failure

- Respiratory depression, bradypnea

- Bronchospasm, Tachypnea

- Pulmonary Hypertension

- Ileus, Constipation, Nausea, Vomiting

- Hypotension, Hypertension. Patients with underlying cardiac

disease may be more susceptible to these adverse effects

- CNS depression

- Tachy, Bradycardia

- Should not be used in patients receiving monoamine oxidase inhibitors