MASSACHUSETTS GENERAL HOSPITAL
Department of Pharmacy
Department of Nursing
Critical Care
| Generic Name: | Isoproterenol HCl |
| Trade Name: | Isuprel |
| Action: | Beta Adrenergic Agonist |
| Indications: | AV Block, sick sinus syndrome Stokes-Adams Syndrome Pulmonary Hypertension Bradycardia Status asthmaticus Extrinsic sympathetic stimulation post cardiac transplantation |
| Administration Guidelines: | |
| Usual Dosage Range and Route: | 0.1 to 20 mcg / min IV as titrated to patient response |
| Standard Concentrations: | 2 mg / 250 ml 4 mg / 250 ml 8 mg / 250 ml Syringe Based, Variable Flow, Continuous microinfusion pump: 1 mg / 50 ml |
| Special Considerations: | - use cautiously in
patients with:
- PA - line monitoring of cardiac output, cardiac index, pcwp, cvp, svr, is encouraged during maintenance infusions - Invasive blood pressure monitoring (e.g. a-line) should be considered when centrally administered vasoactive agents are used or when frequent changes in infusion rate are required. |
| Precautions and Side Effects: | - tachycardia, palpitations,
arrhythmias - angina - skin flushing - restlessness, nervousness, tremors |
Rev 9/00