Generic Name:

Glucagon

Trade Name:

Action:

Positive inotrope

Positive chronotrope

Exogenous glucagon source

Indications:

Hypoglycemia

Beta blocker toxicity refractory to conventional treatment

Administration Guidelines:

Usual Dose and Route

5 mg bolus followed by an infusion of 1 - 5 mg/hr up to 10 mg/hr as titrated to patient response.

Standard Concentration:

50 mg / 250 ml

EW Standard:

Pharmacy mixes for EW

Special Considerations:

- Conventional therapy for beta blocker toxicity includes, but is not limited to, atropine, inotropic agents, and pacemaking.

- Monitor serum & urine electrolytes and serum osmolality as indicated.

- Use with caution in patients with ischemic heart disease.

- Reconstitute vial with sterile water for injection

Precautions and Side Effects:

- Nausea, vomiting

- Hyperglycemia

- Hypokalemia