MASSACHUSETTS GENERAL HOSPITAL

Department of Pharmacy

Department of Nursing

Critical Care

Generic Name:


Potassium Phosphate IV

Trade Name:

 

Action:

Potassium Phosphates Replacement

Indications:

Hypophosphatemia

Administration Guidelines:

Usual Dosage Range and Route:

Maximum Infusion Rate : 13 millimole per hour (19 mEq of potassium)

24 Hour Cumulative : 45 millimole / 24 hours (66meq of potassium)

 

 

Potassium phosphate

Standard Concentration:

Central:

10 millimole / 100ml (14.6 mEq of potassium)

15millimoles/ 100ml = (22 mEq of potassium)

20 millimoles/100ml = (29 mEq of potassium)

30 millimoles/ 100m l = (44 mEq of potassium)

45 millimoles/ 100m l = (66 mEq of potassium)

 

Peripheral:

10 millimole / 100ml = (14.6 mEq of potassium)

15millimoles/ 100ml = (22 mEq of potassium)

20 millimoles/250ml = (29 mEq of potassium)

30 millimoles/250ml = (44 mEq of potassium)

45 millimoles/500ml = (66 mEq of potassium)

Maximum Concentration :

Central:

45 millimole / 100ml (66 mEq of potassium)

 

Peripheral:

30 millimole / 250ml (44 mEq of potassium)

Special Considerations:

· 3 millimoles of Potassium Phosphate= 4.4 mEq of potassium

-Potassium phosphorous should be used with caution in patients receiving IV potassium replacement and or TPN. The total of hourly potassium should be calculated and adjusted if necessary.

-Ionized calcium and phosphorous level must be known prior to infusion and checked 24 hours post-infusion of phosphorus and prior to next dose.

-Hypercalcemia

-Hypocalcemia

-Maintain on oral phosphates when necessary

-Renal Failure

Precautions and Side Effects:

-Monitor Bun, creatinine

- Burning sensation may result at site of injection if administered through peripheral access