“The sick room must be ventilated . . . Poisonous matter is constantly being thrown off by the skin and lungs, and if this poison remains in the room it is reabsorbed by the system and does almost as much harm as if it is poison administered by mouth with a teaspoon.”  

The Care of Children by Elisabeth Robinson, Scovil 1894.
Miss Scovil became an MGH Nurse in 1880.