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CPC Archives 1992 - 1995 | ||||||
| Year | Case # | Date Published | Citation | Diagnosis | Specialties | Patient History |
|---|---|---|---|---|---|---|
| 1992 | 1 | 1/2/1992 | N Engl J Med 1992; 326:44-54 | Pulmonary eosinophilic granuloma. ; Talc crystals embolic to lung, with periarteriolar sclerosis. | Hematology/Oncology; Immunology/Allergy | A 34 year old woman with dyspnea and multiple small cystic areas in the lungs. |
| 1992 | 2 | 1/9/1992 | N Engl J Med 1992; 326:117-25 | Huntington's disease, grade 3. ; Hippocampal sclerosis, left secondary to ischemia. ; Cerebral infarct, old, small, left parietal cortex. Hydrocephalus ex vacuo. | Neurology/Neurosurgery | Chorea and progressive dementia in an 88 year old woman. |
| 1992 | 3 | 1/16/1992 | N Engl J Med 1992; 326:184-91 | Wegener's granulomatosis of trachea. | Immunology/Allergy; Pulmonary/Thoracic Surgery | A 40 year old woman with intermittent hemoptysis and mucosal ulceration found on bronchoscopic examination |
| 1992 | 4 | 1/23/1992 | N Engl J Med 1992; 326:255-63 | Multiple myeloma, with secondary myelofibrosis. | Hematology/Oncology; Ophthalmology | Pancytopenia, splenomegaly and retinal hemorrhage in a 52 year old diabetic man |
| 1992 | 5 | 1/30/1992 | N Engl J Med 1992; 326:324-36 | Mycoplasma pneumonia, with diffuse alveolar damage and disseminated intravascular coagulation. | Infectious Disease; Pulmonary/Thoracic Surgery; Hematology/Oncology; Pediatrics; Vascular medicine | A 20 year old man with diffuse pulmonary infiltrates and disseminated intravascular coagulation. |
| 1992 | 6 | 2/6/1992 | N Engl J Med 1992; 326:397-405 | Pick's lobar atrophy (Pick's disease). | Neurology/Neurosurgery | A 67 year old man with aphasia and memory loss followed by progressive dementia. |
| 1992 | 7 | 2/13/1992 | N Engl J Med 1992; 326:472-81 | Systemic mastocytosis. | Hematology/Oncology; Dermatology; Cardiology/Cardiac Surgery; Primary Care | A 57 year old man with a twenty year history of episodic headache, flushing, hypotension and occasional syncope |
| 1992 | 8 | 2/20/1992 | N Engl J Med 1992; 326:547-59 | B-cell malignant lymphoma, EBV-associated, disseminated, with involvement of liver, after transplantation of liver. ; Acute tubular necrosis, kidneys. | Transplantation; Hematology/Oncology; Gastroenterology/Abdominal Surgery; Nephrology | A 47 year old man with recurrent fever and fulminant hepatic failure one month after a liver transplant |
| 1992 | 9 | 2/27/1992 | N Engl J Med 1992; 326:624-33 | True aneurysm of left ventricle, congenital. | Cardiology/Cardiac Surgery | Wide complex tachycardia in a 65 year old woman without previous evidence of cardiac disease |
| 1992 | 10 | 3/5/1992 | N Engl J Med 1992; 326:692-9 | Pelvic actinomycosis complicating use of intrauterine device. | OB/GYN; Urology | A 41 year old woman with a swollen left leg pelvic mass and bilateral hydronephrosis. |
| 1992 | 11 | 3/12/1992 | N Engl J Med 1992; 326:750-8 | Bronchioloalveolar carcinoma of lung. Pulmonary interstitial fibrosis, consistent with usual interstitial pneumonitis. | Pulmonary/Thoracic Surgery | Increasing dyspnea and cough in a 77 year old man with interstitial lung disease. |
| 1992 | 12 | 3/19/1992 | N Engl J Med 1992; 326:816-24 | Arteriovenous fistula of spinal dura (Type 1). (Foix-Alajouanine syndrome). | Neurology/Neurosurgery | A 64 year old woman with the abrupt onset of paraparesis after ten months of increasing episodic leg weakness. |
| 1992 | 13 | 3/26/1992 | N Engl J Med 1992; 326:875-84 | Congenital pulmonary lymphangiectasis, with focal interstitial fibrosis. | Pulmonary/Thoracic Surgery; Pediatrics; OB/Gyn | A full-term newborn boy with chronic respiratory distress. |
| 1992 | 14 | 4/2/1992 | N Engl J Med 1992; 326:936-44 | Arteriovenous malformation of large and small intestine, with focal rupture and hemorrhage. | Gastroenterology/Abdominal Surgery | A 37 year old man with a third bout of major hematochezia. |
| 1992 | 15 | 4/9/1992 | N Engl J Med 1992; 326:1008-15 | Hemorrhagic pseudocyst of adrenal gland. | Urology; Endocrinology | A 23 year old woman with a painful mass in the right adrenal region |
| 1992 | 16 | 4/16/1992 | N Engl J Med 1992; 326:1070-6 | Acute and chronic bacterial osteomyelitis and diskitis, with epidural abscess (Staphylococcus aureus). (Paronychia). | Orthopedics/Musculoskeletal; Neurology/Neurosurgery; Infectious Disease | A 27 year old woman with pain in the neck and shoulder and clumsiness of the hand. |
| 1992 | 17 | 4/23/1992 | N Engl J Med 1992; 326:1137-46 | Refractory anemia with ring sideroblasts with thrombocythemia (essential thrombocythemia, myelodysplastic type). | Hematology/Oncology | Repeated bouts of hematochezia in an 80 year old hypertensive man. |
| 1992 | 18 | 4/30/1992 | N Engl J Med 1992; 326:1204-12 | Necrotizing arteritis with anti-myeloperoxidase antibodies, consistent with Churg-Strauss syndrome. | Immunology/Allergy; Neurology/Neurosurgery; Pulmonary/Thoracic Surgery | Asthma, peripheral neuropathy, and eosinophilia in a 52-year-old man. |
| 1992 | 19 | 5/7/1992 | N Engl J Med 1992; 326:1276-84 | Paraneoplastic pemphigus, with involvement of skin, mucosa (buccal cavity), larynx, and trachea. Malignant lymphoma, small-cell lymphocytic type, with plasmacytoid features consistent with Waldenstrom's macroglobulinemia. | Dermatology; Hematology/Oncology; Immunology/Allergy | A 56-year-old man with Waldenstrom's macroglobulinemia and cutaneous and oral vesicles. |
| 1992 | 20 | 5/14/1992 | N Engl J Med 1992; 326:1342-9 | Eosinophilic gastritis. | Gastroenterology/Abdominal Surgery; Immunology/Allergy | A 24-year-old man with asthma and bouts of epigastric pain, nausea, and vomiting. |
| 1992 | 21 | 5/21/1992 | N Engl J Med 1992; 326:1417-24 | Multiple myeloma, presenting as plasmacytoma of bone extending into sphenoid sinus. | Hematology/Oncology; Neurology/Neurosurgery; Immunology/Allergy | A 65-year-old man with a mass that involved the base of the skull. |
| 1992 | 22 | 5/28/1992 | N Engl J Med 1992; 326:1480-9 | Cat scratch disease, with encephalopathy | Infectious Disease; Neurology/Neurosurgery; Hematology/Oncology; Pediatrics | A 6.5 year old girl with status epilepticus, cervical lymphadenopathy, pleural effusions, and respiratory distress. |
| 1992 | 23 | 6/4/1992 | N Engl J Med 1992; 326:1550-7 | Suppurative pericarditis due to Corynebacterium acnes. | Cardiology/Cardiac Surgery; Infectious Disease | A 55 year old man with recurrent pericardial and pleural effusions after aortic-valve replacement. |
| 1992 | 24 | 6/11/1992 | N Engl J Med 1992; 326:1617-23 | Aldosterone-producing adenoma of left adrenal gland. | Endocrinology; Nephrology; Urology | A 52 year old man with hypertension, hypokalemia, and an adrenal mass. |
| 1992 | 25 | 6/18/1992 | N Engl J Med 1992; 326:1682-92 | Hepatic cirrhosis, probably end-stage primary biliary cirrhosis. Plexogenic pulmonary hypertension due to cirrhosis. Cor pulmonale. | Gastroenterology/Abdominal Surgery; Pulmonary/Thoracic Surgery | A 33-year-old woman with cirrhosis and right ventricular failure. |
| 1992 | 26 | 6/25/1992 | N Engl J Med 1992; 326:1762-9 | Infarction in distribution of left middle cerebral artery, secondary to atherosclerotic stenosis of cavernous portion of left internal carotid artery. | Neurology/Neurosurgery | A 38-year-old obese man with hypertension, diabetes mellitus, and slowly progressive right hemiparesis. |
| 1992 | 27 | 7/2/1992 | N Engl J Med 1992; 327:40-4 | Diverticulitis, with peridiverticular abscess and peritonitis. | Gastroenterology/Abdominal Surgery; Infectious Disease; Pediatrics | A 20-year-old man with recent intermittent abdominal pain, constipation, and diarrhea. |
| 1992 | 28 | 7/9/1992 | N Engl J Med 1992; 327:107-16 | Metastatic malignant melanoma, encephalitic form, in leptomeninges and cerebral cortex. | Neurology/Neurosurgery; Dermatology | A 45-year-old man with confusion, seizures, and few focal findings. |
| 1992 | 29 | 7/16/1992 | N Engl J Med 1992; 327:182-91 | Crohn's disease of ileum, exacerbated by infectious gastroenteritis. | Gastroenterology/Abdominal Surgery; Infectious Disease | A 76-year-old woman with recurrent diarrhea several months after treatment for tropical sprue. |
| 1992 | 30 | 7/23/1992 | N Engl J Med 1992; 327:261-268. | INFANTILE STRIATONIGRAL DEGENERATION, WITH CEREBELLAR DEGENERATION, FAMILIAL | Pediatrics; Neurology/Neurosurgery | A boy 4.5 after having had, for most of his life, a progressive neurodegenerative disorder, characterized by a gradual loss of motor and verbal skills, with generalized seizures, myoclonus, and final deterioration to a nonverbal, quadriparetic state. |
| 1992 | 31 | 7/30/1992 | N Engl J Med 1992; 327:338-45 | Coronary artery disease, with thrombosis of right coronary artery and acute myocardial infarction. Rupture of posteromedial papillary muscle, with mitral regurgitation. | Cardiology/Cardiac Surgery | A 68-year-old man with acute mitral regurgitation. |
| 1992 | 32 | 8/6/1992 | N Engl J Med 1992; 327:412-8 | Aneurysm of persistent sciatic artery, with thrombosis. | Orthopedics/Musculoskeletal; Vascular Surgery | A 72-year-old man with a mass in the posterior thigh. |
| 1992 | 33 | 8/13/1992 | N Engl J Med 1992; 327:481-5 | Nephrolithiasis, bilateral, with ureteral obstruction. | Nephrology; OB/GYN; Urology | A 34 year old woman with endometriosis and bilateral hydronephrosis. |
| 1992 | 34 | 8/20/1992 | N Engl J Med 1992; 327:548-57 | Emery-Dreifuss muscular dystrophy. | Cardiology/Cardiac Surgery; Neurology/Neurosurgery; Pediatrics | A 19 year old man with progressive proximal muscle weakness, contractures, and cardiac abnormalities. |
| 1992 | 35 | 8/27/1992 | N Engl J Med 1992; 327:628-35 | Abetalipoproteinemia. | Pediatrics; Gastroenterology/Abdominal Surgery | An eight month old boy with diarrhea and failure to thrive. |
| 1992 | 36 | 9/3/1992 | N Engl J Med 1992; 327:790-9 | Acquired immunodeficiency syndrome. Toxoplasma myocarditis and myositis of colonic muscularis propria. Cytomegalovirus colitis. Bronchopneumonia, focal. | Infectious Disease; Cardiology/Cardiac Surgery | Abrupt development of cardiac enlargement and respiratory distress in a 31-year-old man with AIDS. |
| 1992 | 37 | 9/10/1992 | N Engl J Med 1992; 327:873-80 | Rheumatoid lung disease, with pleuritis, interstitial lymphocytic infiltrate, arterial hypertension, and venous sclerosis. | Pulmonary/Thoracic Surgery; Immunology/Allergy | A 68-year-old woman with rheumatoid arthritis and pulmonary hypertension. |
| 1992 | 38 | 9/17/1992 | N Engl J Med 1992; 327:943-50 | Systemic amyloidosis, AL kappa type, with involvement of heart, autonomic nerves, kidneys, and lungs. | Hematology/Oncology; Neurology/Neurosurgery; Cardiology/Cardiac Surgery; Nephrology; Pulmonary/Thoracic Surgery | A 72 year old woman with orthostatic hypotension, syncope, and marked proteinuria. |
| 1992 | 39 | 9/24/1992 | N Engl J Med 1992; 327:1014-21 | Syndrome of polyneuropathy, organomegaly, endocrinopathy, M component, and skin changes (POEMS). Atypical lymphoid hyperplasia with some features of angiofollicular hyperplasia, suggestive of follicular lymphoma. | Neurology/Neurosurgery; Hematology/Oncology; Gastroenterology/Abdominal Surgery | A 49 year old woman with peripheral neuropathy, hepatosplenomegaly, and intermittent abdominal pain. |
| 1992 | 40 | 10/1/1992 | N Engl J Med 1992; 327:1081-7 | Melioidosis of spleen, with multiple granulomas. | Infectious Disease; Hematology/Oncology | A 43 year old Cambodian man with several years of recurrent bouts of fever and abdominal pain. |
| 1992 | 41 | 10/8/1992 | N Engl J Med 1992; 327:1153-9 | Subvalvular membranous aortic stenosis. | Pediatrics | A 3 year old boy with obstructive uropathy and a heart murmur of increasing intensity. |
| 1992 | 42 | 10/15/1992 | N Engl J Med 1992; 327:1226-33 | Primary pulmonary hypertension, with acute necrotizing vasculitis and hemorrhage. Cor pulmonale. | Pulmonary/Thoracic Surgery; Immunology/Allergy; Cardiology/Cardiac Surgery | A 59 year old woman with severe, progressive dyspnea. |
| 1992 | 43 | 10/22/1992 | N Engl J Med 1992; 327:1298-305 | Motor neuron disease, progressive muscular atrophy type. | Neurology/Neurosurgery; Psychiatry | A 70-year-old man with progressive muscle weakness and agitated depression. |
| 1992 | 44 | 10/29/1992 | N Engl J Med 1992; 327:1370-6 | Lymphocytic myocarditis, patchy, focal, and mild, with human immunodeficiency virus infection. | Cardiology/Cardiac Surgery; Infectious Disease; Immunology/Allergy | A 60-year old man with HIV infection, persistent diarrhea, and intractable respiratory failure. |
| 1992 | 45 | 11/5/1992 | N Engl J Med 1992; 327:1442-8 | Mucinous adenocarcinoma of colon metastatic to right ventricle, with pulmonary tumor emboli and infarcts. | Gastroenterology/Abdominal Surgery; Cardiology/Cardiac Surgery; Pulmonary/Thoracic Surgery | A 75 year old man with carcinoma of the colon and a right ventricular mass. |
| 1992 | 46 | 11/12/1992 | N Engl J Med 1992; 327:1512-8 | Tracheopathia osteoplastica. Saber-sheath trachea | Pulmonary/Thoracic Surgery | A 48 year old woman with a narrowed trachea. |
| 1992 | 47 | 11/19/1992 | N Engl J Med 1992; 327:1581-8 | Tethered cord syndrome; Occult myelomeningocele, with dermal sinus | Neurology/Neurosurgery; OB/Gyn; Urology | A 25 year old man with chronic intermittent coccygeal pain and mild bladder dysfunction. |
| 1992 | 48 | 11/26/1992 | N Engl J Med 1992; 327:1667-75 | Malignant lymphoma, B-cell type, involving lung and retroperitoneum. | Hematology/Oncology; Pulmonary/Thoracic Surgery | An 82 year old man was admitted to the hospital because of abdominal pain, nausea, and vomiting. |
| 1992 | 49 | 12/3/1992 | N Engl J Med 1992; 327:1740-9 | Plasma-cell dyscrasia (multiple myeloma), with Bence Jones lambda light-chain immunoglobulin G in serum and urine. Systemic amyloidosis involving heart, lungs, liver, spleen, kidneys, gastrointestinal tract, pancreas, and adrenal glands. Coronary atherosc | Immunology/Allergy; Hematology/Oncology; Cardiology/Cardiac Surgery | A 70 year old man with multisystem failure after a sextuple coronary artery bypass graft procedure. |
| 1992 | 50 | 12/10/1992 | N Engl J Med 1992; 327:1801-9 | Malignant lymphoma, small lymphocytic type. Hodgkin's disease, chronic lymphocyte-depletion type,; (Richter's syndrome) | Hematology/Oncology | A 54 year old man with fever of unknown origin four years after a diagnosis of lymphocytic lymphoma. |
| 1992 | 51 | 12/17/1992 | N Engl J Med 1992; 327:1869-74 | Erosion of prosthetic vascular graft into distal terminal ileum. | Gastroenterology/Abdominal Surgery; Cardiology/Cardiac Surgery | A 78 year old woman with recurrent gastrointestinal bleeding after several intra-abdominal vascular operations. |
| 1992 | 52 | 12/24/1992 | N Engl J Med 1992; 327:1938-46 | Cryptogenic organizing pneumonia. | Pulmonary/Thoracic Surgery | Progressive pulmonary air space disease in a 71 year-old man with emphysema. |
| 1993 | 1 | 1/7/1993 | N Engl J Med 1993; 328:48-55 | Interstitial eosinophilic pneumonitis. | Pulmonary/Thoracic Surgery; Pediatrics | A 7 year-old girl with recurrent bouts of sore throat, cough, dyspnea, and fever. |
| 1993 | 2 | 1/14/1993 | N Engl J Med 1993; 328:121-8 | Acquired anti-factor VIII antibody. | Hematology/Oncology; Orthopedics/Musculoskeletal | A 72-year-old woman with a coagulopathy and bilateral thigh masses. |
| 1993 | 3 | 1/21/1993 | N Engl J Med 1993; 328:195-202 | Tuberculosis of mediastinal lymph nodes. | Pulmonary/Thoracic Surgery; Infectious Disease | A 51-year-old Ethiopian woman with myalgia, weight loss, and mediastinal lymphadenopathy. |
| 1993 | 4 | 1/28/1993 | N Engl J Med 1993; 328:266-75 | B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma, with infiltration of orbital muscle, soft tissue, and lacrimal gland. | Hematology/Oncology; Ophthalmology | A 73 year old man with severe facial pain, visual loss, decreased ocular motility, and an orbital mass. |
| 1993 | 5 | 2/4/1993 | N Engl J Med 1993; 328:340-6 | Clostridum septicum myonecrosis (gas grangrene). Adenocarcinoma, cecum, with metastasis to right kidney and pericolic and peripancreatic lymph nodes. | Gastroenterology/Abdominal Surgery | An 81-year-old man with pain and crepitus in the shoulder. |
| 1993 | 6 | 2/11/1993 | N Engl J Med 1993; 328:422-8 | Late reactivation of acute hematogenus osteomyelitis (Staphylococcus aureus) of femur (with pulmonary abscesses). | Orthopedics/Musculoskeletal; Infectious Disease; Pulmonary/Thoracic Surgery | A 69-year-old woman with a sclerotic lesion of the femur and pulmonary nodules. |
| 1993 | 7 | 2/18/1993 | N Engl J Med 1993; 328:496-502 | (McCune-Albright syndrome, with polyostotic fibrous dysplasia, pigmented skin lesions, and sexual precocity. ; Testicular tubule maturation. | Endocrinology; Pediatrics | A 6 year-old boy with multiple bone lesions, repeated fractures, and sexual precocity. |
| 1993 | 8 | 2/25/1993 | N Engl J Med 1993; 328:566-73 | Cysticercosis involving basal cisterns of brain. | Infectious Disease; Neurology/Neurosurgery | A 62 year old Cape Verdean woman with blurred vision, diplopia, a suprasellar mass, and lymphocytic meningitis. |
| 1993 | 9 | 3/4/1993 | N Engl J Med 1993; 328:640-7 | Left atrial myxoma. | Cardiology/Cardiac Surgery | A 23-year-old man with fever, dyspnea, extensive bilateral pulmonary infiltrates, and a question of heart failure. |
| 1993 | 10 | 3/11/1993 | N Engl J Med 1993; 328:717-25 | Subacute bacterial endocarditis, with multiple cerebral emboli and cerebral infarcts. Mycotic aneurysm, left middle cerebral artery, ruptured, with fatal intracerebral and subarachnoid hemorrhage. Parkinson's disease, with neuronal degeneration in substan | Infectious Disease; Neurology/Neurosurgery; Cardiology/Cardiac Surgery | A 67-year-old man with mitral regurgitation and an abrupt onset of ataxia and fever. |
| 1993 | 11 | 3/18/1993 | N Engl J Med 1993; 328:792-800 | Sarcoidosis, involving heart, lungs, mediastinal lymph nodes, spleen, liver, and kidney. (?Alcoholic cardiomyopathy. ; | Pulmonary/Thoracic Surgery; Cardiology/Cardiac Surgery; Nephrology; Gastroenterology/Abdominal Surgery | A 52-year-old man with cardiomyopathy and pulmonary disease. |
| 1993 | 12 | 3/25/1993 | N Engl J Med 1993; 328:869-76 | Desquamative interstitial pneumonitis. | Pulmonary/Thoracic Surgery | A 44-year-old man with pulmonary disease and proctitis. |
| 1993 | 13 | 4/1/1993 | N Engl J Med 1993; 328:951-8 | Microscopic polyarteritis (microscopic polyangitis), with pauci-immune necrotizing and crescentic glomerulonephritis and alveolar hemorrhage (associated with antineutrophil cytoplasmic antibodies). | Pulmonary/Thoracic Surgery; Nephrology; Immunology/Allergy | A 74-year-old woman with rapidly progressing renal failure after an upper respiratory tract infection. |
| 1993 | 14 | 4/8/1993 | N Engl J Med 1993; 328:1031-5 | Primary hyperparathyroidism, with brown tumor of right humerus. | Endocrinology | A 74-year-old woman with hyperparathyroidism and an osteolytic lesion in the humerus. |
| 1993 | 15 | 4/15/1993 | N Engl J Med 1993; 328:1107-14 | Stromal tumor of low-grade malignancy, of small intestine. | Gastroenterology/Abdominal Surgery | A 58-year-old man with recurrent lower gastrointestinal bleeding for over two years. |
| 1993 | 16 | 4/22/1993 | N Engl J Med 1993; 328:1183-90 | Anti-glomerular basement membrane nephritis with pulmonary hemorrhage (Goodpasture's syndrome). | Pulmonary/Thoracic Surgery; Nephrology; Pediatrics | A 13-year-old girl with gross hematuria four years after a diagnosis of idiopathic pulmonary hemosiderosis. |
| 1993 | 17 | 4/29/1993 | N Engl J Med 1993; 328:1259-66 | Spongiform encephalopathy (Creutzfeldt-Jakob disease), with amyloid (kuru) plaques. | Neurology/Neurosurgery | A 53-year-old woman who died after several years of a dementing illness with intermittent generalized seizures and abnormal movements of the extremities and head. |
| 1993 | 18 | 5/6/1993 | N Engl J Med 1993; 328:1337-43 | Angiosarcoma arising in chronic lymphedema (Stewart-Treves syndrome). | Dermatology; Hematology/Oncology; Orthopedics/Musculoskeletal | A 57-year-old man with chronic lymphedema and enlarging purple cutaneous nodules of the leg. |
| 1993 | 19 | 5/13/1993 | N Engl J Med 1993; 328:1406-14 | Malignant lymphoma, diffuse large-cell type, B lineage, of kidneys, after Hodgkin's disease, nodular-sclerosis type. | Hematology/Oncology; Nephrology | A 39 year old man with bilateral renal masses a few months after treatment for Hodgkin's disease, stage IIA. |
| 1993 | 20 | 5/20/1993 | N Engl J Med 1993; 328:1478-83 | Central giant-cell reparative granuloma of mandible. | Orthopedics/Musculoskeletal; Ear, Nose & Throat | A 23 year old woman with a rapidly enlarging intraoral mass after a tooth extraction. |
| 1993 | 21 | 5/27/1993 | N Engl J Med 1993; 328:1550-8 | Axonal polyneuritis associated with IgA lambda multiple myeloma. | Neurology/Neurosurgery; Hematology/Oncology | A 71 year old man with a rash and severe sensorimotor neuropathy. |
| 1993 | 22 | 6/3/1993 | N Engl J Med 1993; 328: 1625-631 | Malignant lymphoma, diffuse mixed small-cell and large-cell type, of T-cell cytotoxic-suppressor type. | Hematology/Oncology; Ear, Nose & Throat | A 22 year-old male with increasing swelling of the face. |
| 1993 | 23 | 6/10/1993 | N Engl J Med 1993; 328: 1696-702 | Diffuse lymphoid hyperplasia of lungs, peribronchiolar (follicular bronchiolitis) and interstitial (lymphocytic interstitial pneumonitis); | Pulmonary/Thoracic Surgery | A 30 year-old male with a chronic cough and increasing exeritional dyspnea. |
| 1993 | 24 | 6/17/1993 | N Engl J Med 1993; 328: 1770-775 | Ovarian stromal hyperthecosis and hilus-cell hyperplasia, with virilization. Inactive cystic endometrium. | Endocrinology; OB/Gyn | A 56 year-old female with male-pattern baldness and hirsutism. |
| 1993 | 25 | 6/24/1993 | N Engl J Med 1993; 328: 1836-841 | Paget's disease, active, of two vertebras, with pathologic fracture. | Orthopedics/Musculoskeletal; Neurology/Neurosurgery | A 67 year-old male with increasing back pain. |
| 1993 | 26 | 7/1/1993 | N Engl J Med 1993; 329; 43-48 | Radiation-induced osteogenic sarcoma of left femoral artery. | Orthopedics/Musculoskeletal; Vascular Surgery | A 73 year-old male with a contained, ruptured aneurysm of the left femoral artery. |
| 1993 | 27 | 7/8/1993 | N Engl J Med 1993; 329: 117-123 | Cerebral vasculitis involving small vessels, consistent with effect of cocaine. Cerebral hemorrhage. | Neurology/Neurosurgery; Psychiatry; Vascular Medicine | A 32 year-old right-handed male with left hemiplegia. |
| 1993 | 28 | 7/15/1993 | N Engl J Med 1993; 329: 194-98 | Babesiosis. Serologic evidence of Lyme disease. | Dermatology; Hematology/Oncology | A 63 year-old male with fever, chills, fatigue. |
| 1993 | 29 | 7/22/1993 | N Engl J Med 1993; 329: 2164-68 | Actinomycoma of soft tissues of thigh (and of lung). | Infectious Disease | A 54 year old male with a mass in the right thigh and a radiographic density in a lung. |
| 1993 | 30 | 7/29/1993 | N Engl J Med 1993; 329: 343-49 | Eosinophilic gastroenteritis, serosal form. | Gastroenterology/Abdominal Surgery | A 59 year-old female with left-sided abdominal pain |
| 1993 | 31 | 8/5/1993 | N Engl J Med 1993; 329: 417-23 | Granulocytic sarcoma involving bone, soft tissue, and lymph nodes, complicating myelofibrosis with myeloid metaplasia. | Hematology/Oncology; Orthopedics/Musculoskeletal | A 49 year-old male with myelofibrosis with myeloid metaplasia and painful osteolytic lesions of the right femur. |
| 1993 | 32 | 8/12/1993 | N Engl J Med 1993; 329: 488-95 | Lymphocytic myocarditis with fibrosis and biventricular dilatation, compatible with chronic Chagas' heart disease. | Cardiology/Cardiac Surgery; Infectious Disease | A 27 year-old male with syncope. |
| 1993 | 33 | 8/19/1993 | N Engl J Med 1993; 329: 561-68 | Colonic adenocarcinoma, moderately differentiated (with fever of unknown origin). | Gastroenterology/Abdominal Surgery | A 50 year-old male with fever of unknown origin and diarrhea. |
| 1993 | 34 | 8/26/1993 | N Engl J Med 1993; 329: 645-52 | Kaposi's sarcoma of skin and oral mucosa, with extensive metastasis to lung. Pneumocystis carinii pneumonia. (Acquired immunodeficiency syndrome. ; | Pulmonary/Thoracic Surgery; Dermatology; Ear, Nose & Throat; Infectious Disease | A 36 year-old male with the acquired immunodeficiency syndrome (AIDS) with increasing dyspnea and respiratory failure. |
| 1993 | 35 | 9/2/1993 | N Engl J Med 1993; 329: 714-20 | Chronic granulomatous disease. Suppurative granulomatous lymphadenitis due to Serratia marcescens. | Pediatrics; Infectious Disease | A 2 year-old male with lymphadenopathy and fever. |
| 1993 | 36 | 9/9/1993 | N Engl J Med 1993; 329: 792-98 | Parvovirus B19 infection. Large-cell lymphoma. Acquired immunodeficiency syndrome. | Infectious Disease; Hematology/Oncology | A 28 year-old male with acquired immunodeficiency syndrome (AIDS), pancytopenia, and lymphoma. |
| 1993 | 37 | 9/16/1993 | N Engl J Med 1993; 329: 864-71 | Atrial septal defect, surgically corrected. Pulmonary arterial hypertension, marked, with occlusive, microthrombolic, plexogenic, and dilatation lesions of small muscular pulmonary arteries. | Cardiology/Cardiac Surgery; Pulmonary/Thoracic Surgery | A 48 year-old female with a secundum atrial septal defect with severe pulmonary hypertension. |
| 1993 | 38 | 9/23/1993 | N Engl J Med 1993; 329: 948-54 | Atheromatous embolism, with renal and cutaneous involvement. ; (Atherosclerosis, generalized. ; | Nephrology; Dermatology; Cardiology/Cardiac Surgery; Vascular Surgery | A 70 year-old male for further management of a myocardial infarct. |
| 1993 | 39 | 9/30/1993 | N Engl J Med 1993; 329: 1028-32 | Giant-cell aortitis, with descending aortic dissection and rupture. | Cardiology/Cardiac Surgery; Nephrology | An 83 year-old female with severe upper-back pain, hypertension, and anuria. |
| 1993 | 40 | 10/7/1993 | N Engl J Med 1993; 329: 1108-115 | Disseminated Langerhan's-cell histiocytosis (histiocytosis X), involving bone marrow, liver, and skin. | Dermatology; Gastroenterology/Abdominal Surgery; Hematology/Oncology | A 61 year-old female with fever, jaundice, hepatosplenomegaly, and gallstones. |
| 1993 | 41 | 10/14/1993 | N Engl J Med 1993; 329: 1182-189 | Acquired demyelinating neuropathy. ? Chronic inflammatory demyelinating polyradiculopathy. ? Motor neuropathy with multifocal conduction blocks. | Neurology/Neurosurgery | A 66 year-old female with progressive weakness of all extremities. |
| 1993 | 42 | 10/21/1993 | N Engl J Med 1993; 329: 1254-260 | Delayed transfusion reaction. Splenomegaly of unknown cause. | Gastroenterology/Abdominal Surgery | A 62 year-old female with nausea, vomiting, jaundice two weeks after an aortic valvuloplasty. |
| 1993 | 43 | 10/28/1993 | N Engl J Med 1993; 329: 1335-341 | Brain abscess, cerebra, due to Fusobacterium nucleatum and Peptostreptococcus micros. | Neurology/Neurosurgery; Infectious Disease | A 71 year-old female, right handed, with a question of brain tumor.; |
| 1993 | 44 | 11/4/1993 | N Engl J Med 1993; 329: 1411-1416 | Gonococcemia. | Infectious Disease; Dermatology | A 39 year-old male with fever, difuse arthralgia, and purpuric skin lesions. |
| 1993 | 45 | 11/11/1993 | N Engl J Med 1993; 329: 1484-490 | Allergic bronchopulmonary aspergillosis. | Infectious Disease; Pulmonary/Thoracic Surgery | A 23 year-old male with asthma with increased cough with pulmonary infiltrates. |
| 1993 | 46 | 11/18/1993 | N Engl J Med 1993; 329; 1560-566 | Progressive supranuclear palsy. | Neurology/Neurosurgery | A 75 year-old male with right-sided rigidity, dysphagia, dysarthria, and an impaired gait. |
| 1993 | 47 | 11/25/1993 | N Engl J Med 1993; 329; 1639-646 | Diffuse lymphocytic myocarditis (progressing to endomyocardial fibrosis). ; | Cardiology/Cardiac Surgery | A 28 year-old male with recurrent ventricular tachycardia |
| 1993 | 48 | 12/2/1993 | N Engl J Med 1993; 329: 1720-727 | Pulmonary veno-occlusive disease. | Pulmonary/Thoracic Surgery | A 27 year-old female with pulmonary hypertension with increasing right-sided heart failure. |
| 1993 | 49 | 12/9/1993 | N Engl J Med 1993; 329: 1797-804 | Desquamative interstitial pneumonitis, with central bronchiectasis, peribronchiolar fibrosis, and subpleural cysts. | Pulmonary/Thoracic Surgery; Transplantation | A 21 year-old female admitted for a lung transplantation. |
| 1993 | 50 | 12/16/1993 | N Engl J Med 1993; 329: 1873-880 | Bronchiectasis, left lower lobe, saccular and aneurysmal, with collapse and chronic organizing pneumonia. | Pulmonary/Thoracic Surgery | A 46 year-old male with a mass in the lower lobe of the left lung. |
| 1993 | 51 | 12/23/1993 | N Engl J Med 1993; 329: 1946-953 | Intestinal and renal microsporidiosis due to Septata intestinalis. Acquired immunodeficiency syndrome (AIDS). | Nephrology; Infectious Disease; Gastroenterology/Abdominal Surgery | A 36 year-old male with known acquired immunodeficiency syndrome (AIDS) who recently developed fever spikes and an increase in chronic diarrhea. |
| 1993 | 52 | 12/30/1993 | N Engl J Med 1993; 329: 2019-25 | Goodpasture's syndrome, with ANCA and anti-GBM antibodies. Wegener's granulomatosis, involving lungs, kidneys, and spleen. | Pulmonary/Thoracic Surgery; Nephrology; Immunology/Allergy; Pediatrics | A 17 year old female with massive hemoptysis and renal failure. |
| 1994 | 1 | 1/6/1994 | N Engl J Med 1994; 330:51-57 | Schistosomiasis of urinary bladder, active,, caused by Schistosoma haematobium infection. | OB/Gyn; Urology; Gastroenterology/Abdominal Surgery | A 27-year-old woman with secondary infertility and a bladder mass. |
| 1994 | 2 | 1/13/1994 | N Engl J Med 1994; 330: 126-134 | Constrictive pericarditis, idiopathic, recurrent. Myocardial and endocardial fibrosis involving papillary muscle, probably ischemic. Myxomatous change of mitral valve with mitral regurgitation. | Cardiology/Cardiac Surgery | A 31-year-old man with severe mitral regurgitation with congestive failure. |
| 1994 | 3 | 1/20/1994 | N Engl J Med 1994; 330: 196-202 | Crohn's ileocolitis. Acute pancreatitis. | Pediatrics; Gastroenterology/Abdominal Surgery | An 11-year-old boy with recurrent abdominal pain. |
| 1994 | 4 | 1/27/1994 | N Engl J Med 1994; 330:273-280 | Disseminated histoplasmosis. Acquired immunodeficiency syndrome (AIDS). | Gastroenterology/Abdominal Surgery; Infectious Disease; Cardiology/Cardiac Surgery | A 38-year-old man with with bloody diarrhea, weakness and dyspnea. |
| 1994 | 5 | 2/3/1994 | N Engl J Med 1994; 330: 347-353 | Pulmonary eosinophilic granuloma. | Pulmonary/Thoracic Surgery | A 34-year-old woman with dry cough, exertional dyspnea, and interstitial pulmonary disease. |
| 1994 | 6 | 2/10/1994 | N Engl J Med 1994; 330: 420-426 | Pseudomembranous colitis associated with Clostridium difficile toxin. | Pediatrics; Gastroenterology/Abdominal Surgery | A 31-month old girl with fever and diarrhea. |
| 1994 | 7 | 2/17/1994 | N Engl J Med 1994; 330: 490-496 | Prostatic abscess, Cryptococcus neoformans. | Urology | A 55-year-old man with persistent urinary tract infection. |
| 1994 | 8 | 2/24/1994 | N Engl J Med 1994; 330: 557-564 | Legionella longbeachae pnuemonia. Mycobacterium avium complex in bronchial secretions. Lymphoma, well-differentiated lymphocytic, and leukemia. | Pulmonary/Thoracic Surgery; Hematology/Oncology; Infectious Disease | An 84-year-old woman with lymphoma and the recent onset of cough and fever. |
| 1994 | 9 | 3/3/1994 | N Engl J Med 1994; 330: 627-632 | Chronic radiation enteropathy. | Gastroenterology/Abdominal Surgery | An 80-year-old woman with persistent gatrointestinal bleeding after a right colectomy. |
| 1994 | 10 | 3/10/1994 | N Engl J Med 1994; 330: 698-781 | Hodgkin's disease, recurrent, involving stomach and paragastric lymph nodes. | Hematology/Oncology | A 37-year-old woman with treated Hodgkin's disease in remission admitted because of a question of idiopathic thrombocytopenic purpura. |
| 1994 | 11 | 3/17/1994 | N Engl J Med 1994; 330: 775-781 | Plasmodium vivax malaria. Splenomegaly, chronic. | Cardiology/Cardiac Surgery; Infectious Disease | A 35-year-old man, native of Ethiopia, with fever, chills and splenomegaly. |
| 1994 | 12 | 3/24/1994 | N Engl J Med 1994; 330: 847-854 | Henoch--Schonlein purpura. | Hematology/Oncology; Nephrology | A 72-year-old man with chronic cutaneous ulcers and the recent onset of progressive renal failure. |
| 1994 | 13 | 3/31/1994 | N Engl J Med 1994; 330: 920-927 | Multiple myeloma, IgG3-kappa light-chain, with hyperviscosity syndrome and type I cryoglobulinemia. | Hematology/Oncology; Orthopedics/Musculoskeletal | A 62-year-old man with bilateral epistaxis and orthostatic hypotension. |
| 1994 | 14 | 4/7/1994 | N Engl J Med 1994; 330: 997-1002 | Malignant fibrous histiocytoma of pulmonary artery, with embolism and pulmonary infarcts. | Pulmonary/Thoracic Surgery; Hematology/Oncology | A 54-year-old woman with hemoptysis, dyspnea, and a left mediastinal mass. |
| 1994 | 15 | 4/14/1994 | N Engl J Med 1994; 330: 1072-1078 | Autosomal recessive polycystic kidney disease, with congenital hepatic fibrosis. | Pediatrics; Nephrology | A 14-year-old girl with the biochemical features of advanced renal failure. |
| 1994 | 16 | 4/21/1994 | N Engl J Med 1994; 330: 1143-1149 | Cardiac myxoma, right atrial, with extension into left atrium and pulmonary tumor embolism. | Cardiology/Cardiac Surgery; Pulmonary/Thoracic Surgery | A 57-year-old man with chest pain, dyspnea, and a mass in the right ventricle and atrium. |
| 1994 | 17 | 4/28/1994 | N Engl J Med 1994; 330: 1218-1225 | Acquired immunodeficiency syndrome (AIDS). Cytomegalovirus vasculitis of colon with transmural necrosis and peritonitis. Karposi's sarcoma with cytomegalovirus infection of jejunum. | Infectious Disease; Gastroenterology/Abdominal Surgery; | A 38-year-old man with AIDS, abdominal pain and rectal bleeding. |
| 1994 | 18 | 5/5/1994 | N Engl J Med 1994; 330: 1300-1306 | Pulmonary lymphangioleiomyomatosis (tuberous sclerosis). | Pulmonary/Thoracic Surgery | A 37-year-old woman with chronic insterstitial lung disease and a history of spontaneous pneumothorax. |
| 1994 | 19 | 5/12/1994 | N Engl J Med 1994; 330: 1376-1381 | Giant pseudodiverticulum of sigmoid colon. | Gastroenterology/Abdominal Surgery | A 47-year-old woman with intermittent abdominal pain, vomiting and weight loss |
| 1994 | 20 | 5/19/1994 | N Engl J Med 1994; 330: 1439-1446 | Inflammatory pseudotumor of lung. | Pulmonary/Thoracic Surgery; Pediatrics | A girl five years and eight months old with a nodular lesion in the upper lobe of the left lung, recent bouts of fever, and a cough associated with pulmonary infiltrates. |
| 1994 | 21 | 5/26/1994 | N Engl J Med 1994; 330: 1516-1522 | Pulmonary coccidioidomycoma, caviated, with rupture and pneumothorax. | Pulmonary/Thoracic Surgery | A 20-year-old man with recurrent hemoptysis and a pulmonary cavity. |
| 1994 | 22 | 6/2/1994 | N Engl J Med 1994; 330: 1599-1606 | Bronchioloalveolar carcinoma. | Hematology/Oncology; Pulmonary/Thoracic Surgery | A 57-year-old man with extensive bilateral air space disease and a lung biopsy specimen that showed alveolar filling. |
| 1994 | 23 | 6/9/1994 | N Engl J Med 1994; 330: 1671-1676 | Mucinous villous adenomatosis, atypical, involving dilated segment of main pancreatic duct. | Endocrinology | A 37-year-old man with pancreatic-duct lesion and several bouts of acute pancreatitis. |
| 1994 | 24 | 6/16/1994 | N Engl J Med 1994; 330: 1739-1746 | Accute Epstein-Barr-virus infection, with thrombocytopenia. Infectious mononucleosis. | Orthopedics/Musculoskeletal; Infectious Disease; Pediatrics | A 2-year-old boy with thrombocytopenia, leukocytosis, and hepatosplenomegaly. |
| 1994 | 25 | 6/23/1994 | N Engl J Med 1994; 330: 1811-1817 | Hemorrhagic colitis with transmural necrosis, consistent with Escherichia coli serotype O157:H7 infection. | Hematology/Oncology; Gastroenterology/Abdominal Surgery; Infectious Disease | A 54-year-old woman with intractable diarrhea after chemotherapy for carcinoma of the tongue. |
| 1994 | 26 | 6/30/1994 | N Engl J Med 1994; 330: 1887-1893 | Cysticercosis of muscular and intermuscular soft tissue of forearm. | Orthopedics/Musculoskeletal | A 20-year-old woman with a soft tissue mass in the forearm. |
| 1994 | 27 | 7/14/1994 | N Engl J Med 1994; 331: 107-113 | Burkitt's lymphoma, involving mandible, lymph nodes, bone marrow, (spleen), and nervous system. | Hematology/Oncology | A 41-year-old woman with neurologic abnormalities and an osteolytic lesion of the right mandible. |
| 1994 | 28 | 7/21/1994 | N Engl J Med 1994; 331: 181-187 | Lymphocutaneous sporotrichosis. | Infectious Disease | A 51-year-old man with a non-healing finger lesion and regional lymphadenopathy. |
| 1994 | 29 | 7/28/1994 | N Engl J Med 1994; 331: 259-265 | Small-unmyelinated-fiber neuropathy with chronic anhidrosis. | Neurology/Neurosurgery | A 32-year-old man with hypothermia on exercise. |
| 1994 | 30 | 8/11/1994 | N Engl J Med 1994; 331: 383-389 | Gluten-sensitive enteropathy (celiac sprue). | Gastroenterology/Abdominal Surgery | A 74-year-old woman with diarrhea, recurrent dehydration and severe weight loss. |
| 1994 | 31 | 8/18/1994 | N Engl J Med 1994; 331: 460-466 | Hemochromatosis with dilated cardiomyopathy and micronodular cirrhosis of the liver. | Cardiology/Cardiac Surgery | A 25-year-old man with the recent onset of congestive heart failure and atrial fibrillation. |
| 1994 | 32 | 8/25/1994 | N Engl J Med 1994; 331: 528-535 | Small-cell carcinoma of lung, metastatic ot mediastinum, with the Lambert--Eaton myasthenic syndrome. | Orthopedics/Musculoskeletal | A 61-year-old man with muscular weakness. |
| 1994 | 33 | 9/8/1994 | N Engl J Med 1994; 331: 661-667 | Thrombotic thrombocytopenic purpura, with associated extensive acute myocardial necrosis. | Cardiology/Cardiac Surgery | A 41-year-old woman with thrombocytopenia, anemia, and changed mental status. |
| 1994 | 34 | 9/15/1994 | N Engl J Med 1994; 331: 728-734 | Tuberculosis of larynx, Mycobacterium tuberculosis. | Gastroenterology/Abdominal Surgery; Hematology/Oncology | A 38-year-old man with progressive hoarseness. |
| 1994 | 35 | 9/22/1994 | N Engl J Med 1994; 331: 792-800 | Leukocytoclastic vasculitis, due to staphylococcal protein A column therapy. Cerebral infarction of undetermined pathogenesis. | Hematology/Oncology; Vascular Surgery | A 55-year-old woman with idiopathic thrombocytopenic purpura with left hemiparesis. |
| 1994 | 36 | 9/29/1994 | N Engl J Med 1994; 331: 861-868 | Primary malignant lymphoma of the central nervous system, diffuse,large-cell, B-cell type with kappa-light-chain immunoglobulin. | Hematology/Oncology; Neurology/Neurosurgery | A 49-year-old man with an intracranial mass. |
| 1994 | 37 | 10/13/1994 | N Engl J Med 1994; 331: 1005-1012 | Juvenile chronic myelogenous leukemia. | Orthopedics/Musculoskeletal; Pediatrics | A newborn boy with petechiae and massive splenomegaly. |
| 1994 | 38 | 10/20/1994 | N Engl J Med 1994; 331: 1079-1084 | Myositis ossificans. | Orthopedics/Musculoskeletal | A 55-year-old man with a tender left paraspinal mass. |
| 1994 | 39 | 10/27/1994 | N Engl J Med 1994; 331: 1143-1149 | Wegener's granulomatosis, right orbit, soft tissue and breast. | Hematology/Oncology; Vascular Surgery | A 69-year-old woman with a right orbital mass with chronic conjunctivitis. |
| 1994 | 40 | 11/10/1994 | N Engl J Med 1994; 331: 1293-1300 | Polyarteritis nodosa with neuropathy. | Neurology/Neurosurgery; Pulmonary/Thoracic Surgery | A 77-year-old woman with pain in the head and legs, fever, and sweats. |
| 1994 | 41 | 11/17/1994 | N Engl J Med 1994; 331: 1362-1368 | Necrotizing fasciitis due to Escherichia coli, with underlying myositis. | Vascular Surgery; Infectious Disease | A 57-year-old man with evidence of gram-negative bacteremia, with peripheral edema and erythema of the leg with bullae. |
| 1994 | 42 | 11/24/1994 | N Engl J Med 1994; 331: 1437-1444 | Mycoplasma pneumoniae infection. | Pulmonary/Thoracic Surgery; Neurology/Neurosurgery | A 19-year-old man with ascending paresthesias, progressive weakness of the legs, and a rash. |
| 1994 | 43 | 12/8/1994 | N Engl J Med 1994; 331: 1576-1582 | Mantle-cell lymphoma. | Hematology/Oncology; Gastroenterology/Abdominal Surgery | A 52-year-old woman with weakness, diarrhea and lymphadenopathy. |
| 1994 | 44 | 12/15/1994 | N Engl J Med 1994; 331: 1642-1647 | Rheumatoid pleuritis. | Immunology/Allergy; Orthopedics/Musculoskeletal | A 38-year-old woman with severe rheumatoid arthritis and a new left pleural effusion. |
| 1994 | 45 | 12/22/1994 | N Engl J Med 1994; 331: 1703-1709 | Herpes simplex virus type 2, necrotizing lymphadenitis. | Infectious Disease | A 47-year-old man with relapsed acute myelogenous leukemia admitted for an allogeneic bone marrow transplantation. |
| 1994 | 46 | 12/29/1994 | N Engl J Med 1994; 331: 1761-1767 | Adenocarcinoma of lung, arising in a bulla. Bullous emphysema. | Pulmonary/Thoracic Surgery; Hematology/Oncology | A 35-year-old man with increasing exertional dyspnea, recent arthralgia and digital clubbing; and a questionable fungus ball in the right lung. |
| 1995 | 1 | 1/12/1995 | N Engl J Med 1995; 332: 110-115 | Tracheobronchial amyloidoma | Pulmonary/Thoracic Surgery | An 80-year-old man with an enlarging lung tumor of long duration, recurrent bouts of postobstructive pneumonia, and recent respiratory distress. |
| 1995 | 2 | 1/19/1995 | N Engl J Med 1995; 332: 174-179 | Xanthogranulomatous pyelonephritis, extending into perirenal soft tissue. | Nephrology | A 71-year-old man with masses in the pancreas, presacral region, and left kidney, with left hydronephrosis. |
| 1995 | 3 | 1/26/1995 | N Engl J Med 1995; 332: 249-257 | Disseminated Pneumocystis carinii and Mycobacterium avium complex infections involving the spleen and liver. | Infectious Disease | A 29-year-old man with AIDS and multiple splenic abcesses. |
| 1995 | 4 | 2/9/1995 | N Engl J Med 1995; 332: 380-386 | Giant-cell arteritis, consistent with Takayasu's arteritis, with coronary artery involvement. | Cardiology/Cardiac Surgery | A 26-year-old woman with unstable angina 81/2 weeks after a triple coronary-artery bypass procedure. |
| 1995 | 5 | 2/16/1995 | N Engl J Med 1995; 332: 452-459 | Arteritis,unclassified, with giant-cell reaction and multiple infarcts of brain. Peripheral neuropathy, probably secondary to arteritis. | Neurology/Neurosurgery | A 73-year-old right handed man with weakness, drowsiness, headache, and confusion. |
| 1995 | 6 | 2/23/1995 | N Engl J Med 1995; 332: 522-527 | Ovarian cyst, probably follicular, with antenatal torsion, hemorrhagic infarction, autoamputation, and implantation on the midjejunal mesentery. | OB/Gyn; Pediatrics | A one month old girl with an intraabdominal mass. |
| 1995 | 7 | 3/9/1995 | N Engl J Med 1995; 332: 663-671 | Malignant lymphoma, large-cell immunoblastic, B-cell type, with Epstein--Barr viral infection involving the spleen and lymph nodes. Splenic infarcts and extramedullary hematopoiesis. Cytomegalovirus lymphadenitis. (Common variable immunodeficiency. ) (A | Infectious Disease | A 58-year-old man with common variable immunodeficiency, recurrent sinusitis, splenomagaly and mild thrombocytopenia admitted because of severe anemia and jaundice. |
| 1995 | 8 | 3/16/1995 | N Engl J Med 1995; 332: 730-737 | Neurolymphomatosis. | Neurology/Neurosurgery | A 75-year-old man with cranial nerve deficits and a footdrop. |
| 1995 | 9 | 3/23/1995 | N Engl J Med 1995; 332: 804-810 | Fibromuscular dysplasia of superior mesenteric artery. Ischemic colitis. | Gastroenterology/Abdominal Surgery | A 60-year-old man with left-sided abdominal pain and diarrhea. |
| 1995 | 10 | 3/30/1995 | N Engl J Med 1995; 332: 876-881 | Granulosa-cell tumor, adult type, of ovary, with rupture and peritoneal spread. | OB/Gyn | A 56-year-old woman with abdominal pain, a falling hemocrit, and a pelvic mass. |
| 1995 | 11 | 4/13/1995 | N Engl J Med 1995; 332: 1015-1022 | Chronic infective endocarditis, due to Staphylococcus epidermidis. | Infectious Disease; Cardiology/Cardiac Surgery | A 39-year-old man with calcifications around the aortic root, a recent myocardial infarction, and a subsequent congestive heart failure, with increasing aortic regurgitation. |
| 1995 | 12 | 4/20/1995 | N Engl J Med 1995; 332: 1083-1089 | Acute postinfectious glomerulonephritis with arteritis superimposed on diabetic nephropathy. | Nephrology | A 59-year-old man with possible pneumonia and acute renal failure. |
| 1995 | 13 | 4/27/1995 | N Engl J Med 1995; 332: 1153-1159 | Low-grade gastric B-cell lymphoma of mucosa-associated lymphoid tissue (MALT) origin. | Gastroenterology/Abdominal Surgery | A 35-year-old woman with recurrent melena after treatment for a gastric ulcer with positive tests for Helicobacter pylori. |
| 1995 | 14 | 5/11/1995 | N Engl J Med 1995; 332: 1285-1291 | Schwannoma, involving ethmoid sinus and nasal cavity. | Ear, Nose & Throat; Pediatrics | a 12-year-old boy with an obstructive right nasal mass. |
| 1995 | 15 | 5/18/1995 | N Engl J Med 1995; 332: 1363-1370 | Quinidine-induced thrombocytopenia. Cerebral hemorrhage. | Neurology/Neurosurgery | A 70-year-old woman with obtundation, aphasia, and a right hemiparesis. |
| 1995 | 16 | 5/25/1995 | N Engl J Med 1995; 332: 1432-1438 | Sarcoidosis involving the lungs and heart. | Pulmonary/Thoracic Surgery; Immunology/Allergy | A 35-year-old man with recurrent ventricular tachycardia. |
| 1995 | 17 | 6/8/1995 | N Engl J Med 1995; 332: 1566-1572 | Pulmonary hemorrhage, hemosiderosis, and congestive vasculopathy due to mitral regurgitation. | Pulmonary/Thoracic Surgery; Vascular Medicine | A 81-year-old woman with severe pulmonary edema after aortic-valve and mitral-valve replacements. |
| 1995 | 18 | 6/15/1995 | N Engl J Med 1995; 332: 1631-1636 | Squamous-cell carcinoma arising in dermoid cyst of ovary, with invasion of the muscularis of the rectosigmoid colon. Small-cell carcinoma of the lung. | OB/Gyn; Hematology/Oncology; Gastroenterology/Abdominal Surgery | A 59-year-old woman with increasing constipation, abdominal pain, and a rectosigmoid mass. |
| 1995 | 19 | 6/22/1995 | N Engl J Med 1995; 332: 1700-1707 | Pulmonary embolic and lymphangitic carcinomatosis of breast origin. | Pulmonary/Thoracic Surgery | A 55-year-old woman with acute respiratory distress and thrombocytopenia. |
| 1995 | 20 | 6/29/1995 | N Engl J Med 1995; 332: 1773-1780 | Progressive multifocal leukoencephalopathy. | Neurology/Neurosurgery | A 66-year-old right handed man with a right hemiparesis with sensory involvement, aphasia, and agitation with intermittent somnolence. |
| 1995 | 21 | 7/13/1995 | N Engl J Med 1995; 333: 113-119 | Group A beta-hemolytic streptococcus (Streptococcus pyogenes), with compartment and toxic shock syndromes. | Infectious Disease; Orthopedics/Musculoskeletal | A 33-year-old man with fever and increasing pain in the right leg. |
| 1995 | 22 | 7/20/1995 | N Engl J Med 1995; 333: 175-181 | Mediastinal hemorrhage, spontaneous, in parathyroid tissue. | Ear, Nose & Throat | A 82-year-old woman with odynophagia and a large superior mediastinal mass. |
| 1995 | 23 | 7/27/1995 | N Engl J Med 1995; 333: 241-248 | Pulmonary tuberculosis, nonreactive and miliary, with diffuse alveolar damage (adult respiratory distress syndrome), with milliary tuberculosis in the liver, spleen, adrenal glands, bone marrow and kidneys. Kaposi's sarcoma of the jejunum. | Pulmonary/Thoracic Surgery | A 44-year-old woman with severe respiratory distress, bilateral pulmonary infiltrates, and increasing pancytopenia. |
| 1995 | 24 | 8/10/1995 | N Engl J Med 1995; 333: 369-377 | Mixed connective-tissue disease, with diffuse alveolar damage, interstitial pneumonitis, pulmonary hypertension, epicarditis, esophageal fibrosis, and sclerodactyly. | Immunology/Allergy; Pulmonary/Thoracic Surgery; Ear, Nose & Throat; Dermatology | A 46-year-old woman admitted to be considered for a lung transplantation, with severe pulmonary hypertension. |
| 1995 | 25 | 8/17/1995 | N Engl J Med 1995; 333: 441-447 | Lymphocytic hypophysitis. | Neurology/Neurosurgery Endocrinology | A 44-year-old woman with headache, blurred vision and intersellar mass. |
| 1995 | 26 | 8/24/1995 | N Engl J Med 1995; 333: 507-511 | Osteomyelitis, acute and chronic, of the femur, with a soft-tissue abscess caused by Streptococcus milleri. | Orthopedics/Musculoskeletal | A 29-year-old woman a pathologic fracture of the right femur. |
| 1995 | 27 | 8/31/1995 | N Engl J Med 1995; 333: 579-586 | Ganglioneuroblastoma of the adrenal gland. Opsoclonus-myoclonus-ataxia syndrome, paraneoplastic. | Pediatrics; Neurology/Neurosurgery | A 29-month-old girl with increasing ataxia and abnormal eye movements. |
| 1995 | 28 | 9/14/1995 | N Engl J Med 1995; 333: 715-721 | Cecal diverticulum, acquired. | Gastroenterology/Abdominal Surgery | A 69-year-old woman with recurrent pain in the right lower abdominal quadrant and radiological evidence of a cecal abnormality. |
| 1995 | 29 | 9/21/1995 | N Engl J Med 1995; 333: 784-791 | Splenosis. | Gastroenterology/Abdominal Surgery | A 65-year-old man with Hodgkin's disease of the anterior mediastinum and the radiographic finding of a pelvic mass. |
| 1995 | 30 | 9/28/1995 | N Engl J Med 1995; 333: 862-868 | Multiple myeloma, with IgG-kappa serum M component. Cryoglobulinemia, type I. (Overlap syndrome of calcinosis, Raynaud's phenomenon, esophageal dysmotility, sclerodactyly, and telangiectasia (CREST), and systemic lupus erythematosus. | Orthopedics/Musculoskeletal; Immunology/Allergy | A 69-year-old woman systemic lupus erythematosis and painful lesions on the feet. |
| 1995 | 31 | 10/12/1995 | N Engl J Med 1995; 333: 992-999 | Intravascular lymphotosis, with predominant involvement of central nervous system. | Vascular Surgery; Neurology/Neurosurgery; Vascular Medicine | A 43-year-old man with increasing leg pain, bladder and bowel incontinence, and confusion. |
| 1995 | 32 | 10/19/1995 | N Engl J Med 1995; 333: 1066-1072 | Crohn's disease of the esophagus. | Ear, Nose & Throat | A 78-year-old woman with worsening dysphagia and odynophagia. |
| 1995 | 33 | 10/26/1995 | N Engl J Med 1995; 333: 1135-1143 | Granulomatous angiitis of the central nervous sytem. | Neurology/Neurosurgery Hematology/Oncology | A 43-year-old right-handed paraplegic man with increasing confusion and aphasia, fatigue, weight loss and decubitus ulcers. |
| 1995 | 34 | 11/9/1995 | N Engl J Med 1995; 333: 1273-1279 | Arteriovenous malformation of the small intestine. Subacute cholecystitis, with ulceration. Cholelithiasis. | Gastroenterology/Abdominal Surgery | A 77-year-old woman with chronic gastrointestinal bleeding with increasing weakness and dyspnea. |
| 1995 | 35 | 11/16/1995 | N Engl J Med 1995; 333: 1340-1346 | Silicatosis of the lung. | Pulmonary/Thoracic Surgery | A 55-year-old man with increasing dyspnea and abnormal radiographs of the chest. |
| 1995 | 36 | 11/23/1995 | N Engl J Med 1995;333:1406-12 | Progressive muscular atrophy | A 61-year-old man with increasing weakness in all extremities | |
| 1995 | 37 | 11/30/1995 | N Engl J Med 1995; 333: 1485-1493 | Acute disseminated encephalomyelitis (postviral encephalomyelitis). Cerebral infarct, recent. | Neurology/Neurosurgery Pediatrics | A 6-year-old boy with a rash, meningismus, and diplegia. |
| 1995 | 38 | 12/14/1995 | N Engl J Med 1995; 333: 1625-1630 | Multiple myeloma with bilateral carpal tunnel syndrome probaby due to secondary amyloid deposition. | Orthopedics/Musculoskeletal; Immunology/Allergy | a 68-year-old right handed man with parethesias and severe pain in the hands. |
| 1995 | 39 | 12/21/1995 | N Engl J Med 1995; 333: 1695-1702 | Scurvy. | Primary Care | A 72-year-old man with exertional dyspnea, fatigue and extensive echymoses and purpuric lesions. |
| 1995 | 40 | 12/28/1995 | N Engl J Med 1995; 333: 1764-1769 | Solitary cecal ulcer. | Gastroenterology/Abdominal Surgery | A 71-year-old woman with abdominal pain. |