| 2004 |
1 |
1/8/2004 |
N Engl J Med 2004; 350: 166-176 |
Lepromatous leprosy |
EMG; Neurology; ID |
A woman with asymmetric, painful neuropathy |
| 2004 |
2 |
1/15/2004 |
N Engl J Med 2004; 350: 267-275 |
Osteosarcoma of mandible. |
Oromaxillofacial Surgery; Hematology/Oncology |
A man admitted with pain and swelling of the jaw |
| 2004 |
3 |
1/22/2004 |
N Engl J Med 2004; 350: 394-402 |
Bladder Cancer; Management of bladder cancer with bladder sparing
therapy. |
Urology, Oncology |
A man with invasive transitional-cell carcinoma of the bladder |
| 2004 |
4 |
1/29/2004 |
N Engl J Med 2004; 350: 494-502 |
Orbital rhabdomyosarcoma |
Pediatrics; Oncology |
A boy with an orbital rhabdomyosarcoma |
| 2004 |
5 |
2/12/2004 |
N Engl J Med 2004; 350: 707-716 |
Stroke involving the right middle cerebral artery, with the malignant
middle-cerebral-artery edema syndrome. |
Neurosurgery |
A man with slurred speech and left hemiparesis |
| 2004 |
6 |
2/19/2004 |
N Engl J Med 2004; 350: 810-821 |
Burns |
Surgery; Burns |
A woman with extensive, deep burns from a nightclub fire |
| 2004 |
7 |
2/26/2004 |
N Engl J Med 2004; 350: 924-932 |
Melanoma with atypical nevi with germline mutation |
Oncology; Dermatology |
A woman with multiple pigmented lesions and a personal and family
history of melanoma |
| 2004 |
8 |
3/11/2004 |
N Eng J Med 2004; 350: 1131-1138 |
M. TB involving peripancreatic lymph nodes. |
Gastroenterology, Infectious Disease |
A man with abdominal pain, fever, and a mass in the region of the
pancreas |
| 2004 |
9 |
3/18/2004 |
N Eng J Med 2004; 350: 1236-1247 |
Influenza A infection with rhabdomyolysis, severe; myoglobinuria;
viral tracheobronchitis and pneumonia; virus-associated cardiac changes
("borderline myocarditis") and catecholamine-induced myonecrosis;
pericardial effusion. Disseminated intravascular coagulation. Hepatic
centrilobular necrosis. Cardiac hypertrophy of unknown cause.
|
Pediatrics; Infectious Disease |
A man with respiratory symptoms and shock |
| 2004 |
10 |
3/25/2004 |
N Eng J Med 2004; 350: 1339-1347 |
Acute myeloid leukemia with multilineage dysplasia after a myelodysplastic
syndrome. |
Hematology/Oncology; Dermatology |
A man with acute myeloid leukemia and fever after chemotherapy |
| 2004 |
11 |
4/8/2004 |
N Eng J Med 2004; 350: 1550-1559 |
Severe lupus nephritis with mixed proliferative and membranous features
(World Health Organization class IV or V), with high activity and
moderate chronicity indexes. |
Renal |
A boy with rash, edema, and hypertension |
| 2004 |
12 |
4/15/2004 |
N Eng J Med 2004; 350: 1666-1674 |
Proximal aortic disection, associated with pregnancy |
Cardiology |
A woman with acute onset of pain in the chest |
| 2004 |
13 |
4/22/2004 |
N Eng J Med 2004; 350: 1764-1775. |
Kaposiform hemangioma with Kasabach-Merritt syndrome. |
Hematology/Oncology; Pediatrics; Dermatology |
A newborn girl with a large cutaneous lesion, thrombocytopenia,
and anemia |
| 2004 |
14 |
4/29/2004 |
N Eng J Med 2004; 350: 1882-1893 |
Progressive multifocal leukoencephalopathy. |
Infectious Disease; Neurology |
A man with progressive neurological deficits |
| 2004 |
15 |
5/13/2004 |
N Eng J Med 2004; 350: 2081-2087 |
Lymphoblastic lymphoma |
Oncology |
A man with bilateral testicular enlargement |
| 2004 |
16 |
5/20/2004 |
N Eng J Med 2004; 350: 2181-2189 |
Small fiber neuropathy. |
Neurology |
A woman with numbness and pain in the feet and legs |
| 2004 |
17 |
5/27/2004 |
N Eng J Med 2004; 350: 2281-2290 |
Cardiac arrest due to a pulmonary embolus. |
Emergency Medicine |
A woman with cardiac arrest several weeks after an ankle fracture |
| 2004 |
18 |
6/10/2004 |
N Eng J Med 2004; 350: 2500-2509 |
Adenocarcinoma of the rectum, stage T3N2M0 |
Surgery; Radiation Oncology |
A man with rectal bleeding and a 2-cm mass in the rectum |
| 2004 |
19 |
6/17/2004 |
N Eng J Med 2004; 350: 2604-2612 |
Precursor B acute lymphoblastic leukemia with eosinophilia and t(5;
14) (q31; q32) translocation |
Oncology |
A boy with fatigue and eosinophilia |
| 2004 |
20 |
6/24/2004 |
N Eng J Med 2004; 350: 2699-2706 |
Uterine prolapse. |
OB/Gyn |
A woman with pelvic-floor relaxation after a second vaginal delivery |
| 2004 |
21 |
7/8/2004 |
N Eng J Med 2004; 351: 171-178 |
Prostate cancer |
Oncology; Genitourinary, Urology |
A man with metastatic carcinoma refractory to hormone therapy |
| 2004 |
22 |
7/15/2004 |
N Eng J Med 2004; 351: 279-287 |
Tuberculosis |
Internal Medicine, Infectious Disease |
A woman with pericardial effusion |
| 2004 |
23 |
7/22/2004 |
N Eng J Med 2004; 351: 380-387 |
Methemoglobin reductase deficiency |
Pulmonary; Anesthesiology |
A woman with low oxygen saturation |
| 2004 |
24 |
7/29/2004 |
N Eng J Med 2004; 351: 488-495 |
Inverted Meckel's diverticulum of small bowel |
Gastroenterology |
A man with recurrent gastrointestinal bleeding |
| 2004 |
25 |
8/12/2004 |
N Eng J Med 2004; 351: 696-705 |
Evaluation of the obese patient (nutritional, psychological); Medical
management of obesity and its complications; Surgical management of
obesity |
Surgery |
A woman with severe obesity, diabetes and hypertension |
| 2004 |
26 |
8/19/2004 |
N Eng J Med 2004; 351: 809-817 |
Large-cell undifferentiated carcinoma of the lung, stage IIIA (T1N2M0) |
Oncology; Thoracic Surgery |
A woman with cough and a lung nodule |
| 2004 |
27 |
8/26/2004 |
N Eng J Med 2004; 351: 912-922 |
Multisystem atrophy (MSA). Cerebral arteriolar sclerosis |
Neurology |
A woman with a disturbances in gait, cognition, and autonomic function |
| 2004 |
28 |
9/9/2004 |
N Eng J Med 2004; 351: 1120-1130 |
Familial hemophagocytic lymphohistiocytosis (HLH) caused by a mutation
in the perforin gene. |
Pediatrics; Genetics, Neonatology |
Newborn twins with thrombocytopenia, coagulation defects, and hepatosplenomegaly |
| 2004 |
29 |
9/16/2004 |
N Eng J Med 2004; 351:1240-1248 |
Bacterial endocarditis with myocardial abscess due to Strep. Milleri. |
Cardiology/Cardiac Surgery |
A woman with acute onset of chest pain followed by fever |
| 2004 |
30 |
9/23/2004 |
N Eng J Med 2004; 351:1333-1341 |
Pernicious Anemia |
Hematology/Oncology |
A woman with paresthesias of the rms and legs |
| 2004 |
00 |
10/7/2004 |
N Engl J Med 2004; 351:1548-1563 |
Normal Laboratory Values |
Normal Laboratory Values |
Normal Laboratory Values |
| 2004 |
31 |
10/14/2004 |
N Engl J Med 2004; 351:1667-1675 |
Hepatopulmonary syndrome due to the Abernethy malformation, type
1 |
Pediatrics; Pulmonary; Gastroenterology |
A boy with hypoxemia |
| 2004 |
32 |
10/21/2004 |
N Engl J Med 2004; 351: 1779-1787 |
Gastrointestinal stromal tumor |
Oncology; Gastroenterology |
A man with a large retroperitoneal mass |
| 2004 |
33 |
10/28/2004 |
N Engl J Med 2004; 351:1875-1882 |
Anaplastic oligodendroglioma with allelic loss of chromosomes 1p
and 19q |
Neurosurgery |
A man with a seizure and frontal-lobe brain lesion |
| 2004 |
34 |
11/11/2004 |
N Engl J Med 2004; 351:2102-2110 |
Papillary transitional-cell carcinoma of the renal pelvis, low grade |
Genitourinary; Urology; Oncology |
A man with right flank pain and hematuria |
| 2004 |
35 |
11/18/2004 |
N Engl J Med 2004; 351: 2219-2227 |
Nephrogenic fibrosing dermopathy |
Dermatology |
A man with end-stage renal disease and thickened skin |
| 2004 |
36 |
11/25/2004 |
N Engl J Med 2004; 351: 2319-2326 |
Congenital abnormalities due to a chromosomal imbalance, karotype
46, XY, rec (16)dup(16q)inv(16)(p13q22)pat, resulting from the recombination
between the normal chromosome 16 and the inverted chromosome 16 in
the patient's father. |
Pediatrics; Genetics |
An infant with hypospadias and failure to thrive |
| 2004 |
37 |
12/9/2004 |
N Engl J Med 2004; 351: 2531-2538 |
Right ovary: papillary serous cystadenocarcinoma, grade 2 to 3 of
3, arising as a polypoid intracystic mass in a serous tumor containing
benign, typical borderline, and micropapillary borderline areas. Left
ovary: serous borderline tumor, typical type, small. Uterus, omentum,
and lymph nodes: no evidence of cancer. |
Pathology; OB/Gyn, Oncology |
A woman with postmenopausal bleeding and a cystic ovarian mass |
| 2004 |
38 |
12/16/2004 |
N Engl J Med 2004; 351: 2637-2645 |
Plasma-cell myeloma |
Oncology |
A man with a large tumor of the skull. |
| 2004 |
39 |
12/23/2004 |
N Engl J Med 2004; 351: 2741-2749 |
Smoking-related interstitial lung disease (respiratory bronchiolitus
with interstitial lung-disease-desquamative interstitial pneumonitis) |
Pulmonary |
A woman admitted because of yellow sputum and worsening dyspnea. |
| 2004 |
40 |
12/30/2004 |
N Engl J Med 2004; 351: 2851-2859 |
Nephropathy with thin and focally disrupted glomerular basement
membranes and decreased a3 and a5 chains of type IV collagen, consistent
with a carrier state of X-linked Alport's syndrome |
Nephrology |
A woman with long standing hematuria. |
| 2005 |
1 |
1/13/2005 |
N Engl J Med 2005; 352:185-194 |
Primary diffuse large B-cell lymphoma of brain. |
Neurology; Oncology |
A woman with difficulty walking, headache and nausea |
| 2005 |
2 |
1/20/2005 |
N Engl J Med 2005; 352: 274-283 |
Acute Myeloid Leukemia (AML), not otherwise categorized, with normal
karyotype, mutation of the FLT3 tyrosine kinase domain, and cytoplasmic
localization of NPM |
Hematology/Oncology |
A woman with headache, stiff neck, and photophobia |
| 2005 |
3 |
1/27/2005 |
N Engl J Med 2005; 352: 393-403 |
Celiac disease |
Pediatrics; Pediatric Endocrinology, Gastroenterology |
A boy with recent slowing of growth and delayed puberty |
| 2005 |
4 |
2/10/2005 |
N Engl J Med 2005; 352: 609-615 |
Mucocutaneous leishmaniasis due to infection by Leishmania viannia
braziliensis |
Infectious Disease |
A man with nasal congestion, swelling and pain |
| 2005 |
5 |
2/17/2005 |
N Engl J Med 2005; 352: 709-716 |
Invasive endocarditis, possibly due to bartonella |
Emergency Medicine; Cardiology |
A man with depression and sudden shortness of breath |
| 2005 |
6 |
2/24/2005 |
N Engl J Med 2005; 352: 817-825 |
Adenocarcinoma of the esophagus with gastric linitis plastica and
functional duodenal obstruction |
Oncology; Gastroenterology, Palliative Care |
A man with esophageal cancer and nausea, vomiting and intractable
hiccups |
| 2005 |
7 |
3/10/2005 |
N Engl J Med 2005; 352: 1025-1032 |
Functional adrenal cortical adenoma |
Endocrinology, Oncology |
A woman with incidentally discovered adrenal nodule |
| 2005 |
8 |
3/17/2005 |
N Engl J Med 2005; 352: 1122-1129 |
Osteoid Osteoma |
Radiology, Oncology |
A boy with pain in the right thigh |
| 2005 |
9 |
3/24/2005 |
N Engl J Med 2005; 352: 1238-1246 |
Hypersensitivity pneumonitis due to M. avium complex infection (hot-tub
lung). |
Pulmonary; Infectious Disease |
A man with acute respiratory failure |
| 2005 |
10 |
3/31/2005 |
N Engl J Med 2005; 352: 1358-1364 |
Human granulocytic ehrlichiosis (A. phagocytophilum infection). |
Infectious Disease |
A man with weakness and pain in the legs |
| 2005 |
11 |
4/14/2005 |
N Engl J Med 2005; 352: 1579-87 |
Balanced chromosomal translocation - 46 XX, t(1;18)(q42.1;m11.2)
- resulting in an unbalanced fetal transkocation - 46, XY, der( 18)
t(1;18) (q42.1;p11.2) mat. |
OB/Gyn, Genetics |
A woman with a fetal trisomy 18 |
| 2005 |
12 |
4/21/2005 |
N Engl J Med 2005; 352: 1697-1704 |
Mediastinal large-cell lymphoma |
Hematology/Oncology; Pathology |
A woman with a mediastinal mass |
| 2005 |
13 |
4/28/2005 |
N Engl J Med 2005; 352: 1800-1808 |
Neurofibromatosis type 1 affecting the patient and his nephew, with
multiple spinal neurofibromas. |
Genetics, Neurology |
A man with weakness of the limbs and multiple tumors of spinal nerves |
| 2005 |
14 |
5/12/2005 |
N Engl J Med 2005; 352: 2003-2012 |
Systemic small-vessel vasculitis involving small vessels and small
arteries; probably immune-complex vasculitis |
Gastroenterology, Ophthalmology, Rheumatology |
A man with fever and blurred vision. |
| 2005 |
15 |
5/19/2005 |
N Engl J Med 2005; 352: 2111-2119 |
Systemic amyloidosis involving the heart and colon, in the setting
of a monoclonal gammopathy; probably AL amyloidosis |
Renal, Cardiology; Dermatology |
A man with shortness of breath, edema, and proteinuria |
| 2005 |
16 |
5/26/2005 |
N Engl J Med 2005; 352: 2223-2231 |
Pheochromocytoma |
Pediatric Nephrology |
A girl with headaches and hypertension |
| 2005 |
17 |
6/9/2005 |
N Engl J Med 2005; 352: 2425-2434 |
Sickle Cell disease with acute chest syndrome, caused by infarction
of the bone marrow and embolization to the lungs |
Medicine, Pulmonary; Hematology |
A woman with back pain and respiratory failure |
| 2005 |
18 |
6/16/2005 |
N Engl J Med 2005; 352: 2535-2542 |
Endometriosis associated with a surgical scar. |
OB/Gyn, surgery |
A woman with a painful mass in the abdomen |
| 2005 |
19 |
6/23/2005 |
N Engl J Med 2005; 352: 2628-2636 |
Tsunami -related aspiration pneumonia with lung and brain abcesses,
probably polymicrobial. |
Infectious Disease; Pediatrics; Neurology |
Respiratory distress and hemiparesis after a tsunami.
|
| 2005 |
20 |
6/30/2005 |
N Engl J Med 2005; 352: 2734-2741 |
Ductal carcinoma of pancreas, with residual microscopic tumor after
chemoradiation therapy. Pancreatic intraepithelial neoplasia, grade
3, present at the distal resection margin. Resection margins and lymph
nodes free of invasive carcinoma. |
Heme/Onc, Gastroenterology |
A man with locally advanced pancreatic cancer. |
| 2005 |
21 |
7/14/2005 |
N Engl J Med 2005; 353:189-98 |
Neonatal giant-cell hepatitis with bridging fibrosis and early regenerative
nodules, with iron deposition in hepatocytes and Kupffer cells (consistent
with - but not diagnostic of - hemochromatosis) |
Pediatrics; OB/Gyn |
A male infant with jaundice and thrombocytopenia |
| 2005 |
22 |
7/21/2005 |
N Engl J Med 2005; 353: 287-295 |
Encephalomyelitis due to West Nile Virus. CLL with involvement of
the lymph nodes, bone marrow, spleen, lung, kidney, liver, heart,
prostate, and hypoglossal canal. |
Neurology/Neurosurgery; Infectious Disease |
A man with cough, fever, and altered mental status |
2005
|
23 |
7/28/2005 |
N Engl J Med 2005; 353: 401-410 |
Hepatocellular carcinoma |
Surgery; Oncology, Gastroenterology |
A man with a mass in the liver |
| 2005 |
24 |
8/11/2005 |
N Engl J Med 2005; 353: 617-22 |
Breast cancer |
Hematology/Oncology |
A woman with early -stage breast cancer |
| 2005 |
25 |
8/18/2005 |
N Engl J Med 2005; 353: 713-22 |
Portal vein thrombosis; B. fragilis sepsis |
Infectious Disease |
A man with prolonged fevers and weight loss |
| 2005 |
26 |
8/25/2005 |
N Engl J Med 2005; 353: 824-32 |
Hypertrophic cardiomyopathy |
Emergency Medicine; Cardiology |
A man with sudden loss of consciousness while jogging |
| 2005 |
27 |
9/8/2005 |
N Engl J Med 2005; 353: 1042-50 |
Creutzfeldt-Jakob disease |
Infectious Disease; Neurology/Neurosurgery |
An man with a gait disturbance, altered mental status and insomnia |
| 2005 |
28 |
9/15/2005 |
N Engl J Med 2005; 353: 1148-57 |
Churg-Strauss syndrome |
Renal |
A man with weight loss, weakness, cough and a rash on the legs |
| 2005 |
29 |
9/22/2005 |
N Engl J Med 2005; 353: 1275-84 |
Dermatomyositis; Large B-cell lymphoma of spleen |
Internal Medicine; Oncology |
A man with periorbital swelling, skin rash, and weakness |
| 2005 |
30 |
9/29/2005 |
N Engl J Med 2005; 353: 1387-94 |
Bartonella henselae infection (cat scratch disease) in an immunocompromised
host. |
Infectious Disease; Dermatology |
A man with low grade fever and axillary lymphadenopathy |
| 2005 |
31 |
10/13/2005 |
N Engl J Med. 2005; 353:1605-13 |
Type II cryoglobulinemia with renal disease. |
Rheumatology, Renal, Dermatology |
A 60-year-old man with skin lesions and renal insufficiency. |
| 2005 |
32 |
10/20/2005 |
N Engl J Med. 2005; 353:1725-32 |
HIV infection, asymptomatic |
Infectious Disease; OB/Gyn |
A 34-year-old HIV-positive woman who desired to become pregnant |
| 2005 |
33 |
10/27/2005 |
N Engl J Med. 2005; 353:1836-44 |
Osler-Weber-Rendu syndrome (hereditary hemorrhagic telangiectasia)
and juvenile polyposis |
Gastroenterology |
A 43-year-old man with lower gastrointestinal bleeding.
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page last updated 11/03/05 |
