2005 News Releases
inhalers adopted more slowly for minority patients and children
23, 2005 Inhaled steroid medications for asthma, which
have greatly reduced the need for patients to be hospitalized, were
significantly less likely to be prescribed for minority patients
and children during the years soon after their introduction.
Glucose Control Cuts Heart Disease by Half in Type 1 Diabetes
21, 2005 Intensive glucose control lowers the risk of
heart disease and stroke by about 50 percent in people with type
1 diabetes, researchers report in the December 22, 2005, issue of
the New England Journal of Medicine.
test can accurately diagnose heart failure in patients with kidney
14, 2005 A large-scale analysis has shown that a blood
test previously found useful in diagnosing or ruling out heart failure
in emergency room patients remains effective in patients with chronic
Brudnoy Fund receives $400,000 bequest from Brudnoy estate
8, 2005 The David Brudnoy Fund for AIDS Research at MGH
has received $400,000 from the estate of the well-known and respected
Boston radio commentator and talk show host.
structure associated with fear inhibition also may influence personality
28, 2005 The relationship between the size of a brain
structure and the ability to recover from traumatic experiences
also may influence overall personality type, according to an MGH
investigators named to Scientific American 50
25, 2005 Two MGH researchers have been named to the 2005
Scientific American 50, the magazine's annual list of outstanding
leaders in science and technology.
multi-center study confirms value of blood test to diagnose heart
17, 2005 A large-scale international study has demonstrated
the usefulness of a blood test to confirm or exclude the diagnosis
of acute heart failure in emergency room patients and shows that
the test also can identify patients at a higher risk for death.
generated in the adult brain learn to respond to novel stimuli
15, 2005 New brain cells that develop in the olfactory
system of adult mice appear to play a role in the brain different
from that of older neurons, flexibility that suggests such newly-generated
cells could be induced to integrate into other regions of the brain.
associated with structural changes in brain
11, 2005 The regular practice of meditation appears to
produce structural changes in areas of the brain associated with
attention and sensory processing.
patient marks a milestone with new heart
4, 2005 John Scripter walked into the MGH Friday to celebrate
a remarkable milestone - the 20 year anniversary with his transplanted
Map Brings New Insights Into Human Disease, Evolution
26, 2005 In several papers published this week, an international
set of collaborators announce substantial advances in relating human
genetic variation to disease and understanding human evolutionary
Awards Nearly $30 Million for Research Facilities Improvement Projects
25, 2005 The National Center for Research Resources announced
today it will award nearly $30 million for 10 Research Facilities
Improvement Program projects across the country.
Cancer Institute Announces $35 Million in Awards to 12 Cancer Nanotechnology
17, 2005 The National Cancer Institute today announced
funding for a major component of its $144.3 million, five-year initiative
for nanotechnology in cancer research.
doctor awarded for outstanding service to the Latino community
11, 2005 Ernesto Gonzalez, MD, is one of five Latinos
being recognized by Boston City Councillor Felix Arroyo this year.
patients with mild symptoms may still need clot-dissolving drug
6, 2005 A new study confirms that acute stroke patients
who do not receive clot-dissolving medication only because their
symptoms are mild or improving may face a significant risk of death
National Initiatives Aimed At Eliminating Racial and Ethnic Disparities
in Health Care Treatment Unveiled Today
6, 2005 In an effort to move discussion about reducing
racial and ethnic disparities in health care from theory to practice,
a group of national health care experts announced their efforts
today to identify and test specific interventions that will significantly
reduce disparities over the next three years.
release stimulant effective for long-term ADHD treatment
3, 2005 A new study has found that an all-day, extended-release
stimulant for treating attention-deficit hyperactivity disorder
remains effective for up to two years without significant side effects.
Cancer Institute Awards $26.3 Million to Establish Seven Centers
of Cancer Nanotechnology Excellence
3, 2005 The National Cancer Institute today announced
the implementation of a major component of its $144.3 million five-year
initiative for nanotechnology in cancer research.
named by NHLBI as Specialized Center for Cell-Based Therapy for
Heart, Lung and Blood Diseases
29, 2005 Massachusetts General Hospital is one of three
U.S. academic medical centers to receive grants under a National
Heart, Lung and Blood Institute program supporting research into
garden at MGH Cancer Center welcomes visitors
29, 2005 This fall, the Massachusetts General Hospital
Cancer Center is welcoming patients and families to enjoy the Howard
Ulfelder, MD, Healing Garden overlooking Boston.
identifies women at risk of inherited breast or ovarian cancer
26, 2005 A simplified way for patients to report and
update their family medical histories could help identify women
who have inherited genetic mutations that increase their risk for
breast or ovarian cancer.
General Hospital launches magazine that examines medicine's leading
23, 2005 Massachusetts General Hospital this week is
launching a national quarterly magazine that explores the latest
developments in biomedical research, promising clinical applications
and health policy.
resident physicians feel unprepared to care for culturally diverse
6, 2005 Although resident physicians responding to a
national survey acknowledge the importance of accommodating the
needs of today's diverse patient population, many do not feel prepared
to address cross-cultural issues they commonly face in practice.
final report confirms letrozole's benefit for breast cancer patients
6, 2005 The complete analysis of data from an international
trial of the drug letrozole (Femara) confirms earlier reports that
the drug reduced the recurrence of breast cancer in women previously
treated with tamoxifen.
basis of inflammation could lead to improved trauma treatment
31, 2005 A multi-institutional research collaborative
has begun to decipher the complex interplay of genes that underlies
the body's response to major injuries.
aspirin use reduces risk for colorectal cancer
23, 2005 A new report finds that regular, long-term aspirin
use can significantly reduce the risk of colorectal cancer. However,
the benefit requires more than a decade of treatment and is strongest
at dose levels associated with a greater risk of side effects.
Imaging Technology Shown to Detect Pancreatic Inflammation in Type
1 Diabetes and Its Reversal in Animal Models
18, 2005 Recent experiments by Joslin Diabetes Center
and MGH researchers offer hope that physicians may one day be able
to identify individuals with preclinical type 1 diabetes and assess
the effectiveness of therapies.
expression levels may reveal stage of Huntington's disease
16, 2005 A survey of the genome of patients with Huntington's
Disease has identified potential markers of the progression of this
devastating neurological disorder.
marrow may be source of new egg-cell generation in adult mammals
27, 2005 Last year MGH researchers announced surprising
findings that female mice retained the ability to make new egg cells
into adulthood. Now the same investigators report a potential source
for the production of these cells - stem cells in the bone marrow.
of brain structure could signal vulnerability to anxiety disorders
11, 2005 The size of a particular structure in the brain
may be associated with the ability to recover emotionally from traumatic
describes potential problem with new drug for seizures, pain
6, 2005 A serious adverse event experienced by a participant
in a clinical trial may raise a new caution about the use of antiepileptic
drugs for conditions other than epilepsy.
Better Than FDG PET at Detecting Liver Tumors
6, 2005 Significantly more and smaller liver tumors can
be detected by contrast-enhanced MRI when compared to whole-body
FDG PET, say researchers from Massachusetts General Hospital.
ablation is effective long-term treatment for kidney tumors
20, 2005 MGH researchers have shown that radiofrequency
ablation - a minimally invasive way of destroying tissue - is an
effective, longlasting treatment for small kidney tumors in selected
Glucose Control Lowers CVD by About 50 Percent in Diabetes
12, 2005 A significantly lower risk of heart disease
can now be added to the list of proven long-term benefits of tight
glucose control in people with type 1 diabetes.
Retinopathy Occurs in Pre-Diabetes
12, 2005 Diabetic retinopathy has been found in nearly
8 percent of pre-diabetic participants in the Diabetes Prevention
Significantly Reduces the Need for Appendectomy
1, 2005 An MGH study finds that use of CT screening can
signficantly reduce the number of unnecessary appendectomies performed.
factor GM-CSF significantly improves Crohn's disease symptoms
2005 A drug that stimulates a specific part of the immune
system significantly reduced Crohn's disease symptom severity and
improved quality of life after 56 days of daily injections.
may not be major driver of hospital cost increases
2005 Although the use of medical imaging has increased
substantially in recent years, an MGH study finds that the contribution
of imaging to overall hospital costs has remained steady.
Kisco Medical Group, Massachusetts General Hospital announce collaboration
2005 The Mount Kisco Medical Group in New York has become
a clinical affiliate of Massachusetts General Hospital and the Massachusetts
General Physicians Organization.
class of drugs may treat lung tumors resistant to Iressa and Tarceva
2005 A new class of drugs that block the epidermal growth
factor receptor on lung cancer cells may get around the growing
problem of resistance to current targeted therapy drugs.
dairy foods may help reduce risk of type 2 diabetes
2005 The consumption of low-fat dairy foods may reduce
men's risk of developing type 2 diabetes, according to a study from
researchers at Massachusetts General Hospital, Harvard School of
Public Health and Brigham and Women's Hospital.
primary care residents feel unprepared to provide preventive counseling
2005 Many young physicians completing residency training
in primary care specialties do not feel prepared to counsel patients
in areas such as depression, substance abuse and domestic violence.
renowned voice surgeon and team open MGH Voice Center
2005 The new MGH Voice Center was recently established
within the MGH Department of Surgery to integrate a range of clinical
services for patients with voice disorders.
of MGHfC autism clinic receiving special recognition from the Doug
Flutie Jr. Foundation
2005 Margaret Bauman, MD, pediatric neurologist at MassGeneral
Hospital for Children, is accepting the Doug Flutie Jr. Award tomorrow
at the 6th Annual Autism Update.
spectroscopy may be superior for determining prostate cancer prognosis
15, 2005 A new way of evaluating prostate tumors with
magnetic resonance spectroscopy may help physicians and patients
choose the best treatment strategy.
test can accurately diagnose heart failure in emergency patients
11, 2005 A new blood test that measures a particular
marker of cardiac distress can markedly improve the ability to diagnose
congestive heart failure.
factor may help tumors prepare the way for spread to lymph nodes
4, 2005 Production of the protein VEGF-A, already known
to stimulate the growth of blood vessels associated with tumors,
also contributes in unexpected ways to the spread of cancer.
breast cancer prevention study launches in the United States and
30, 2005 A new clinical trial, the first to evaluate
the role of an aromatase inhibitor in the prevention of breast cancer,
has launched in the United States and Canada.
technique identifies vulnerable plaques in cardiac patients
25, 2005 A catheter-based imaging technology called optical
coherence tomography can successfully identify characteristics of
coronary plaques in patients with various cardiac symptoms.
identify genetic pathways essential to RNA interference
24, 2005 An MGH-based research team has identified 80
new genes essential to the process of RNA interference, a powerful
research tool for inactivating genes in plants or animals.
finds anticonvulsant drug poses greater birth-defect risk than suspected
21, 2005 Use of the anticonvulsant drug valproate during
pregnancy may pose a significantly great risk of birth defects than
does use of other antiseizure medications.
potential ability to prevent colon polyps may not apply equally
15, 2005 The association between regular aspirin use
and a reduced risk of precancerous colon polyps may be strongest
in those with alternative forms of a gene involved in the metabolism
study identifies potential Alzheimer's risk gene
2, 2005 Researchers from the MassGeneral Institute for
Neurodegenerative Disorders have identified a gene variant that
may increase the risk of late-onset Alzheimer's disease. They report
that changes in the gene for a protein called ubiquilin-1 are associated
with an increased incidence of Alzheimer's in two large study samples.
of Retrovirus in Blood of ALS Patients
2, 2005 Researchers reported in Neurology this
month that blood samples collected from patients with amyotrophic
lateral sclerosis (ALS) contain evidence of a retroviral enzyme
more often than samples from controls without the disease.
Better Than Current Standard of Practice In Assessing Neoadjuvant
Chemotherapy in Breast Cancer Patients
1, 2005 More breast cancer patients with large tumors
undergo chemotherapy before surgery to reduce the size of their
tumor, and MRI is the best way to predict if the chemotherapy is
working, preliminary results of a study show.
D injections may significantly improve survival in dialysis patients
28, 2005 The administration of intravenous vitamin D
appears to significantly improve the survival of patients on dialysis.
Only half of kidney failure patients currently receive the treatment.
company benefits can help parents meet needs of children with ADHD
28, 2005 Many of the benefits offered by employers could
address the needs of parents of children with ADHD, although they
may be underutilized.
Find Surprising Difference Between Human and Chimp Genomes
10, 2005 Despite 99 percent similarity at the level of
DNA sequence between humans and our nearest relative, chimpanzees,
the locations of DNA swapping between chromosomes, known as recombination
hotspots, are nearly entirely different.
anxiety increases heart disease death risk among women
1, 2005 Women with phobic anxieties, such as the fear
of crowded places, heights or going outside, are at higher risk
for fatal heart disease than women with fewer or no anxieties.
CT Screening Costs Overshadow Benefits
28 , 2005 Whole-body computed tomography (CT) is not
a cost-effective screening method, according to a study published
in the February issue of the journal Radiology.
may be source of versatile stem cells
19, 2005 MGH researchers have followed last year's discovery
that stem cells from the spleen might regenerate insulin-producing
islets with evidence that these cells could produce a greater variety
the genetic babel of brain cells
19, 2005 Researchers at the MGH-HMS Center for Nervous
System Repair have developed a way to distinguish particular brain
cell subtypes and to separate them for genetic analysis with microarrays.
researchers find way of regenerating cells key to hearing
13, 2005 Selectively turning off a protein that controls
the growth and division of cells could allow regeneration of the
cells that convert sound vibrations into nerve impulses, a discovery
that may lead to ways of preventing or treating hearing loss.
network of gastrointestinal immune cells discovered
13, 2005 A previously unknown network of immune cells
has been discovered in the gastrointestinal system by a research
group based in the MGH Center for the Study of Inflammatory Bowel
drugs may be associated with increased risk of diabetes in schizophrenia
3, 2005 Patients treated with the atypical anti-psychotic
agents clozapine and olanzapine may be at an increased risk for
insulin resistance, which is a major risk factor for diabetes.