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Research program to improve battlefield medicine slated for elimination by Department of Defense
Medical Free Electron Laser Program funded for past 20 years

BOSTON - September 18, 2007 - Federal funding for the Medical Free Electron Laser Program (MFEL), which develops advanced laser and optical applications for use in the military and on the battlefield, has been marked for elimination by the Department of Defense.

The program - with current centers at Massachusetts General Hospital, Duke University, Stanford University, the University of California at Irvine, and Vanderbilt University - has been funded for the past 20 years in the range of $16-$20 million a year. The Defense Department's current budget projections show no funding for the program for the next six fiscal years.

In a letter to Pentagon officials, eight U.S. senators, including Senator Edward M. Kennedy (D-Massachusetts) and North Carolina Senator Elizabeth Dole (R-North Carolina), expressed their concern about the Defense Department's proposal. "We can attest to the excellent research track record and the great promise represented by the research currently supported by the MFEL program," the senators wrote.

Disbursing approximately $16 million in the current fiscal year, the MFEL program is a merit-based, peer-reviewed, competitively awarded research program that has funded a wide range of basic research with ties to military medicine - including laser surgery, battle injury monitoring and diagnosis, wound closing and healing, and disease containment.

While the program currently funds centers at MGH, Duke, Stanford, UC Irvine, and Vanderbilt, other institutions which have been funded in the past include the University of Utah, Baylor University, and Northwestern University, among others.

According to R. Rox Anderson, MD, director of the Wellman Center for Photomedicine at Massachusetts General Hospital in Boston, "The MFEL program was intended to fund high-risk, potentially high-reward research to improve military and civilian medicine. The program has been extraordinarily productive by many measures, as recognized by the Defense Department and Congressional staff."

Elimination of program funding will halt promising research nearing delivery, including nerve and blood vessel bonding for limb repair (ready for military clinical trials), and remote diagnosis and/or treatment for blast injuries, head trauma, and Leishmaniasis, a parasitic disease transmitted by sand flies.

"Providing the best possible care to our service men and women includes research and development aimed exactly at solving military medical problems." Anderson said. "The Defense Department's funding recommendation will divert the expertise of some premier biomedical laboratories from this mission at a critical time."

MFEL funding has supported projects that have resulted in the following discoveries, which have both military and civilian applications:

  • "Smart" laser surgery of severe skin burns.
  • Laser treatment of painful and disfiguring scars.
  • Laser treatment of kidney stones (lithotripsy), a common problem made worse among military personnel with dehydration from serving in desert environments.
  • Laser treatments for Pseudofolliculitis Barbae, a condition affecting up to 60 percent of African American men, in which hairs grow back into the skin, causing inflammation and scarring. Close shaving and wearing a gas mask make the condition worse.
  • A light-activated drug (Visudyne®) used to treat macular degeneration, the number one cause of blindness in the United States.
  • A safer laser treatment of glaucoma.
  • Scarless removal of tattoos and foreign body pigments, needed to ensure that qualified enlistees meet military regulations.

Massachusetts General Hospital, established in 1811, is the original and largest teaching hospital of Harvard Medical School. The MGH conducts the largest hospital-based research program in the United States, with an annual research budget of nearly $500 million and major research centers in AIDS, cardiovascular research, cancer, computational and integrative biology, cutaneous biology, human genetics, medical imaging, neurodegenerative disorders, regenerative medicine, systems biology, transplantation biology and photomedicine. MGH and Brigham and Women's Hospital are founding members of Partners HealthCare HealthCare System, a Boston-based integrated health care delivery system.

Media Contacts: Valerie Wencis, MGH Public Affairs

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