Date Prepared:

12/19/08

Name:

Verena Göbel (Bier)

Office Address:

Department of Pediatrics
Mucosal Immunology Laboratory
Massachusetts General Hospital and Harvard Medical School
114 16th Street 114-3503
Charlestown, MA. 02129

Work Phone:

(617) 726-4171

Work FAX:

(617) 726-4172

Work E-Mail:

gobel@helix.mgh.harvard.edu

Education

1984

MD

Freie Universität Berlin and Heinrich-Heine Universität Düsseldorf, Germany

A. Position and Honors.

Postdoctoral Training

1984-1990

Resident and Fellow

Pediatrics and Pediatric Hematology/Oncology (Integrated Programs)

Children’s Hospital and German Cancer Research Center, Universities Düsseldorf and Heidelberg, Germany

1990-1992

Fellow

Molecular Biology

National Cancer Institute, Bethesda, MD

1992-1993

Fellow

Molecular Genetics

Massachusetts General Hospital and Cancer Center, Boston and Charlestown, MA

Visiting Fellow

Pediatric Hematology/Oncology

Licensure and Certification

1991

Medical Examination in Basic and Clinical Sciences, Educational Commission for Foreign Medical Graduates

1992

Board Certification Pediatrics, Germany

1993

Federation Licensing Examination

Academic Appointments

1993-2005

Instructor

Pediatrics

Harvard Medical School, Boston

2006-

Assistant Professor

Pediatrics

Harvard Medical School, Boston

Hospital Appointments

1993-1994

Assistant

Pediatrics

Massachusetts General Hospital, Boston

1994-

Assistant Pediatrician

Pediatrics

Massachusetts General Hospital, Boston

2002-

Consulting Staff

Pediatrics

Spaulding Rehabilitation Hospital, Boston

2003-

Consulting Staff

Pediatrics

Newton-Wellsley Hospital, Newton, MA

Awards and Honors

1990

Fogarty International Foundation Fellowship Award

1991

Lauri Strauss Leukemia Foundation Award

1994

Charles Hood Foundation Award

1995

Clinical Investigator Award

National Cancer Institute

1997

Howard Temin Award

National Cancer Institute

B. Selected peer-reviewed publications

1

Göbel V, Jürgens H, Thomas L, Schwamborn D, Rosin H, Göbel U. Microbial spectrum of blood and body cultures in febrile episodes of children under chemotherapy for treatment of malignant diseases. Pediatr Hematol Oncol 1987; 4: 7-13.

2

Göbel V, Jürgens H, Etspüler G, Kemperdick H, Jungblut RM, Stienen U, Göbel U. Prognostic significance of tumor volume in localized Ewing’s sarcoma of bone in children and adolescents. J Cancer Res Clin Oncol 1987; 113: 187-191.

3

Bier V, Jürgens H, Etspüer G, Exner U, Kühl J, Ritter J, Winkler K, Göbel U. 120 hour continuous infusion of ifosfamide alone and in combination with cisplatinum in chilcren and adolescents. In: Brade W, Nage GA, Seeber S. Ifosfamide in tumor therapy. Basel 1987: 131-138.

4

Jürgens H, Bier V, Harms D, Beck J, Brandeis W, Etspüler G, Gadner HY, Schmidt D, Treuner J, Winkler K, Göbel U. Malignant peripheral neuroectodermal tumors. A retrospective analysis of 42 patients. Cancer 1988; 61: 349-357.

5

Jürgens H, Bier V, Dunst J, Harms D, Jobke A, Kotz R, Kühl J, Müller-Weihrich S, Ritter J, Salzer- Kuntschik M, Sauer R, Sternschulte W, Treuner J, Voûte PA, Weinel P, Winkelmann W, Winkler K, Göbel U. The German Society of Pediatric Oncology Cooperative Ewing’s Sarcoma Studies CESS 81 and 86: report after 6-1/2 years. Klin Pädiatr 1988; 200: 243-252.

6

Semmler W, Gademann G, Bachert-Baumann P, Bier V, Zabel HJ, Lorenz WJ, von Kaick G. In vivo 31phosphorus-spectroscopy of tumors: pre- intra- and post-therapy. RoFo 1988; 149: 369-377.

7

Krammer PH, Behrmann I, Bier V, Daniel P, Dhein J, Falk MH, Garcin G, Klas C, Knipping E, Lucking- Famira KM, Matzku S, Oehm A, Richards S, Trauth BC, Bornkamm GW, Falk W, Möller P, Debatin KM. Apoptosis in the Apo-1 system. Curr Commun Cell Mol Biol 1991; 3: 87-99.

8

Begley CG, Lipkowitz S, Göbel V, Mahon KA, Bertness V, Green AR, Gough NM, Kirsch IR. Molecular characterization of NSCL, a gene encoding a helix-loop-helix protein expressed in the developing nervous system. Proc Natl Acad Sci USA 1992; 89: 38-42.

9

Göbel V, Lipkowitz S, Kozak CA, Kirsch IR. NSCL-2: a basic domain helix-loop-gene expressed in early neurogenesis. Cell Growth and Differ 1992; 3: 143-148.

10

Lipkowitz S, Göbel V, Varterasian ML, Nakahara K, Tchorz K, Kirsch IR. A comparative structural characterization of the human NSCL-1 and NSCL-2 genes. Two basic helix-loop-helix genes expressed in the developing nervous system. J Biol Chem 1992; 267: 21065-21071.

11

Göbel V, Hoffmann HG, Müller-Wiefel DE, Braun A, Ludwig R, Schärer K, Debatin KM. Circulating haematopoietic progenitors during treatment of renal anemia with recombinant human erythropoietin. Eur J Pediatr 1994; 153: 43-48.

12

Rämet M, Pearson A, Manfruelli P, Li X, Koziel H, Göbel V, Chung E, Krieger M, Ezekowitz RA. Drosophila scavenger receptor CI is a pattern recognition receptor for bacteria. Immunity 2001; 15: 1027- 1038.

13

Göbel V, Barrett PL, Hall DH, Fleming JT. Lumen morphogenesis in C. elegans requires the me branecytoskeleton linker erm-1. Dev Cell 2004; 6: 865-873.

14

Barrett PL, Fleming JT, Göbel V. Targeted gene alteration in Caenorhabditis elegans by gene conversion. Nat Genetics 2004; 36: 1231-1237.

15

Barrett PL, Fleming JT, Göbel V. Targeting and altering genes by geneconversion. A practical guide. (in press) Wormbook, ed. The C. elegans Research Community, WormBook, doi/10.1895/wormbook.1.7.1, http://www.wormbook.org

C. Research Support

Completed Research Support (last 3 years)

2003-2005 R03 HD44589

Gobel (PI)

NIH/NICHD

Organ lumen morphogenesis in C. elegans.

Current Research Support

2006-2011 R01 GM078653

Gobel (PI)

NIH

Apical membrane modeling in tubulogenesis.