The long-term goal of my research is to find effective therapeutics for severe intestinal diseases in premature infants. Advanced molecular and cell biology techniques combined with comprehensive systems biology approaches will be used for investigating mechanisms underlying the pathogenesis of preterm infant intestinal disorders, with a particular focus on host-pathogen interactions and developmental anomalies of the intestine in premature infants. Immortal and primary intestine cells and animal models will be used for studies.
I have worked as a physician, an academic researcher, and a teacher in medicine for more than 18 years. My research has focused on: 1) the relationship between breast feeding or other intestinally related nutrients and the development of the immature intestine; and 2) the relationship between mucosal immunity and inflammation diseases including inflammatory bowel disease, asthma, and chronic inflammation-induced pulmonary hypertension.
My teaching experience began at Xinhua Hospital, a teaching hospital affiliated with Shanghai Second Medical University in China. During my work as a physician at Xinhua Hospital, I mentored each year several groups of medical students in clinical practice. As a research fellow at MGH and BWH, I participated in the training of several postdoctoral and clinical fellows. My career goal is to be a principal investigator and to teach students at the undergraduate, graduate, postdoctoral and medical school levels.