Recent Publications
(last 5 years)

Bobby Cherayil, MD

Christina S. Faherty, PhD

Alessio Fasano, MD

Verena Göbel, MD

Bryan P. Hurley, PhD

Beth McCormick, PhD

Hans-Christian Reinecker, MD

Hai Ning Shi, DVM, PhD

W. Allan Walker, MD


Beth McCormick, PhD

  1. Kohler, H, Sakaguchi, T., Hurley, BP, Kase, BJ, Reinecker, HC, McCormick, BA. Salmonella enterica serovarTyphimuriumregulates intercellular junction proteins and facilitates transepithelial neutrophil and bacterial passage. Am. J. Physiol. Gastrointest. Liver Physiol. 2007; 293:G178-187.
  2. Prunier, AL., Schuch, R., Fernandez, RE, Mumy, K., Kohler, H., McCormick, BA, Maurelli, AT. nadA and nadB of Shigella flexneri 5a are anti-virulence loci responsible for the synthesis of quinolinate, a small molecule inhibitor of Shigella pathogenicity. Microbiology 2007; 153: 3513-3518.
  3. Wall, D.M, Nadeau, W.J., Pazos, M.A., Shi, H.N., Galyov, E.E., McCormick, B.A. 2007. Identification of the Salmonella enterica serotype Typhimurium SipA domain responsible for inducing neutrophil recruitment across the intestinal epithelium. Cell. Microbiol. 2007; 9: 2299-2313.
  4. Hurley, B.P., Sin, A., and McCormick, B.A. Adhesion molecules involved in hepoxilin A3 mediated PMN transepithelial migration. Clin. Exp. Immunol. 2008; 151: 297-305.
  5. Zurawski, D.V., Mumy, K.L., Badea, L., Prentice, J.A., Hartland, E.L., McCormick, B.A., Maurelli, A.T. NleE/OspZ family of effector proteins is required for PMN transepithelial migration, a characteristic shared by enteropathogenic Escherichia coli and Shigella flexneri infections. Infect. Immun. 2008;  76: 369-379.
  6. Mumy, K.L., Chen, X., Kelly, C.P., McCormick, B.A. Saccharomyces boulardii interferes with Shigella pathogenesis by post-invasion signaling events. Am. J. Gastrointest. Liver Physiol. 2008; 294: G599-609.
  7. Hurley, B.P. and McCormick, B.A. (2008) Multiple roles of phospholipase A2      during lung infection and inflammation. Infect. Immun. 76;2259-2272.
  8. Canny, G.O. and McCormick, B.A. (2008) Bacteria in the intestine, a helpful resident or an enemy from within? Infect. Immun. 76; 3360-
  9. Srikanth, C.V. and McCormick, B.A. (2008) Interactions of the intestinal epithelium with the pathogen and the indigenous microbiota: A three way crosstalk. Interdisciplinary Perspectives on Infectious Diseases. 626827.
  10. McCormick, B.A. Using Salmonella enterica Serotype Typhimurium to model     intestinal fibrosis. Gastroenterology 2008; 134:872-875.
  11. Siccardi, D, Mumy KL, Wall, DM, Bien, JD, McCormick. Salmonella enterica       serovar Typhimurium modulates P-glycoprotein in the intestinal epithelium. Am. J. Gastrointest. Liver Physiol. 2008; 294:G1392-1340.
  12. Mumy, K.L., Bien J.D., Pazos, M., Gronert, K., Hurley, B.P., McCormick, B.A.     Distinct isoforms of phopholipase A2 mediate the ability of Salmonella enterica   serotype Typhimurium and Shigella flexneri to induce the transepithelial migration of neutrophils. Infect. Immun. 2008; 76:3360-3373.
  13. Pazos, M., Siccardi, D., Mumy, K.L., Bien, J.D., Louie, S., Shi, H.N., Gronert, K.,       Mrsny, R.J., McCormick, B.A. Multi-drug resistance transporter 2 regulates mucosal inflammation by facilitating the synthesis of hepoxillin A3. J. Immunol. 2008; 181:8044-8052.
  14. Fukazawa, A., Alonso, C., Kurachi, K., Gupta, S., Lesser, C., McCormick, B.A.,      Reinecker, H.S. GEF-H1 dependent NF-kB activation in the recognition of Shigella effectors by NOD1. Plos Pathog. 2009; 4:e1000228.
  15. Zurawski, D.V., Mumy, K.L., Faherty, C.S., McCormick, B.A., Maurelli, A.T. Shigella flexneri T3SS effectors OspB and OspF target the nucleus to down- regulate the host inflammatory response via interactions with retinoblastoma protein. Mol. Microbiol. 2009; 71:350-368.
  16. Figueiredo, J, Lawhon, S.D., Gokulan, K., Khare, S., Raffatellu, M., Tsolis, R.M.,      Baumler, A.J., McCormick, B.A. Adams, L.G. Salmonella enterica Typhimurium    SipA induces CXC-chemokine expression through p38MAPK and JUN pathways. Microbes Infect. 2009: 11:302-310.
  17. Mumy KL and McCormick BA. (2009) The role of neutrophils in the event of      intestinal inflammation. Curr Opin Pharmacol. 9:697-701.
  18. Mercado-Lubo R and McCormick BA. A unique subset of Peyer's patches express lysozyme. Gastroenterology. 2010: 138:36-39.
  19. Hurley B.P., Goodman, A.L., Mumy, K.L., Murphy, P., Lory, S., McCormick,   B.A. The two-component sensor response regulator RoxS / RoxR  plays a role in     Pseudomonas aeruginosa interactions with airway epithelial cells. Microbes Infect. 2010;12:190-198.
  20. Srikanth, C.V., Wall, D.M., Maldanado-Contreras, A., Shi, H, Mumy, K.L., and      McCormick, B.A. Salmonella pathogenesis and processing of secreted effectors by caspase-3. Science 2010; 330(6002):390-393.
  21. Mercado-Lubo, R and McCormick, BA (2010) Regulation of Host ABC transporters by enteric pathogens: Role in health and disease. Gut Microbes
  22. McCormick, BA. Adhesion Molecules and Neutrophil Migration. In Preedy, V.R. ed. Adhesion Molecules: Modern Insights into Disease from Molecules to Man, Science Publishers CRC Press, 2010:133-146.
  23. Andrews-Polymenis, H.L., Baumler, A.J., McCormick, B.A., Fang, F.C. (2010) Taming the elephant: Salmonella Biology, Pathogenesis and Prevention. Infect. Immun. 78:2356-69.
  24. Wall, D.M., Srikanth, C.V., McCormick, B.A. Targeting tumors with Salmonela     Typhimurium – Potential for Therapy. (2010) OncoTarget 8:721-728.
  25. Hurley, B.P., Pirzai, W., Mumy, K.L., Gronert, K., and McCormick, B.A.  Selective     eicosanoid generating capacity of cytoplasmic phospholipase A2 in Pseudomonas aeruginosa infected epithelial cells.  Am J Physiol Lung Cell Mol Physiol.  2011; 300:L286-294
  26. McCormick, BA. Shigella gets captured to gain entry. Cell Host Microbe. 2011; 9:449-450.
  27. Agbor, TA, Demma, ZC, Mumy, KL, Bien, JD, McCormick, BA. The ERM protein, Ezrin, regulates neutrophil transmigration by modulating the apical location of MRP2 in response to the SipA effector protein during Salmonella typhimurium infection. Cell Microbiol. 2011; 12:2007-2021.
  28. Hallstrom, K. and McCormick, BA. Salmonella interaction with and passage through the intestinal mucosa: through the lens of the organism (2011) Front Microbiol. 2:88
  29. Agbor, T. and McCormick, BA. Salmonella effectors: Important players modulating host cell function. Cell Microbiol. (2011) 12: 1858-1869
  30. Maldonado-Contreras, AL, and McCormick, BA. Intestinal epithelial cells and     their role in innate mucosal immunity. (2011) Cell Tissue Res. 343:5-12.
  31. McCormick, B.A. and DiRita, V. Invasive and Tissue-damaging Enteric Bacterial      Pathogens: Bloody Diarrhea and Dysentery. In Engleberg, C., Dermody, T, and DiRita, V. eds. 5th edition of Schaechter’s Mechanisms of Microbial Disease. Lippinscott Williams and Wilkins Publishers, 2011
  32. Srikanth, CV., Mercado-Lubo, R., Hallstrom, K., McCormick, BA. Salmonella effector proteins and host cell responses. Cellular and Molecular Life Sciences (2011) 69:3687-3697.
  33. Boll, EJ, Struve, C., Sander, A., Demma, Z., Krogfelt, KA, and McCormick, BA. Enteroaggregative Escherichia coli promotes transepithelial migration of neutrophils through a conserved 12-lipoxygenase pathway. Cell Microbiol. 2012; 14:120-132.
  34. Boll, EJ., Struve, C., Sander, A., Demma, Z., Nataro, JP., McCormick, BA., Krogfelt, KA. The fimbriae of Enteroaggregative E.coli trigger epithelial inflammation in a mouse model of human intestinal xenografts. Journal of Infectious Disease (In Press)