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People of the MIBRC

Principal Investigators:

Bobby Cherayil, MD

Alessio Fasano, MD

Verena Göbel, MD

Bryan Hurley, PhD

Hai Ning Shi, DVM, PhD

W. Allan Walker, MD

Collaborators:

Beth McCormick, PhD

Hans-Christian Reinecker, MD

Curriculum Vitae

W. Allan Walker, MD

Professor of Pediatrics, Chief, Harvard Medical School
Conrad Taff Professor of Nutrition, Harvard Medical School
Professor of Nutrition, Harvard School of Public Health

Phone: 617-726-7988
Fax: 617-724-1731
Email: wwalker@partners.org

EDUCATION:

POSTDOCTORAL TRAINING:

Internship and Residencies:

Research Fellowship:

LICENSURE AND CERTIFICATION:

ACADEMIC APPOINTMENTS:

HOSPITAL APPOINTMENTS:

OTHER PROFESSIONAL POSITIONS AND MAJOR VISITING APPOINTMENTS:

AWARDS AND HONORS:

MAJOR COMMITTEE ASSIGNMENTS:

National and Regional:

Harvard Medical School:

Hospital:

MEMBERSHIPS, OFFICES AND COMMITTEE ASSIGNMENTS IN PROFESSIONAL SOCIETIES:

EDITORIAL BOARDS:

RESEARCH, TEACHING AND CLINICAL CONTRIBUTIONS

1. Gastrointestinal immunology
2. Developmental gastroenterology
3. Protective functions of breast milk
4. Macromolecular transport
5. Nutritional effect on gastrointestinal mucosal barrier
6. Protective nutrients
7. Microbial-epithelial “crosstalk”

NARRATIVE REPORT

My primary responsibilities at Massachusetts General Hospital involve overseeing the Mucosal Immunology and Developmental Gastroenterology Laboratories at Building 114 MGH-East as part of the Combined Program in Pediatric Gastroenterology and Nutrition at Harvard Medical School. These laboratories have seven principal investigators, ten postdoctoral fellows and two graduate students which study oral tolerance, gut inflammation and microbial-epithelial "crosstalk" My research efforts include defining the passive and active protective properties of human breast milk with regard to the protection from disease during the newborn period. I also study the development of human intestinal host defenses using human fetal organ cultures, cell lines, and xenograft transplant models. Specifically, my laboratory has reported that the human fetal epithelium responds inappropriately to both endotoxin and exotoxins which helps to explain an increased incidence and severity of certain inflammatory and secretory diarrheas in this age group.

In 1996, the Faculty Council of Harvard Medical School approved the establishment of a Division of Nutrition at HMS and its affiliated hospitals. I was asked to act as the Director of this division. My responsibilities are to consolidate the nutrition community within HMS for the purpose of establishing a strong undergraduate curriculum and postgraduate education for residents as well as faculty, to encourage basic and clinical research in nutrition and to promote awareness of diet as a preventative approach to the practice of medicine. As part of these responsibilities, I chair a subcommittee on nutrition within the Curriculum Committee of the Harvard Medical School and am Principal Investigator on a NIH supported Harvard Clinical Nutrition Research Center. These interactions also include an active participation in and joint appointment in the Department of Nutrition at Harvard School of Public Health and an affiliated appointment within the Clinical Research Center at M.I.T.

RESEARCH FUNDING INFORMATION:

Past:

Current:

PRINCIPAL CLINICAL AND HOSPITAL SERVICE RESPONSIBILITIES:

MAJOR ADMINISTRATIVE RESPONSIBILITIES:

SELF REPORT OF TEACHING:

1. Local Contribution

a. Medical School Courses

b. Hospital Course and Invited Teaching Presentations

c. Advisory and Supervisory Responsibilities

d. Account of any Leadership

1993 Participant, Post-Graduate Course in Gastroenterology, American Gastroenterological Association

2. Regional, National or International Contributions

a. Invited Presentations

1992 Director, Symposium in Immunophysiology of the Gastrointestinal Tract, Harvard Medical School

b. Professional Leadership Roles Related to Teaching

c. Invited Lectureships (last five years)

Got to Second Page of CV.