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The People of the Moore Lab

Principal Investigator
 
Kathryn J. Moore, PhD

Kathryn Moore is Assistant Professor at Harvard Medical School and a faculty member of the Lipid Metabolism Unit in the Department of Medicine at Massachusetts General Hospital. Dr. Moore received her PhD from McGill University in 1994, where she was the recipient of the T.W. Cameron Award for Excellence for her research on host-pathogen interactions. Her subsequent postdoctoral work at Brigham and Women’s Hospital (1994-1996) and Massachusetts General Hospital (1996-2000) focused on macrophage regulation of innate immune responses during infection, autoimmunity and sterile inflammation.

Dr. Moore has been the recipient of numerous awards, including the Claflin Distinguished Scholar Award and the Ellison New Scholar in Aging Award. She is actively involved in activities of the American Heart Association, and serves on the American Heart Association’s Leadership Committee for Arteriosclerosis, Thrombosis and Vascular Biology, which provides input into the AHA’s science positions, guides the Council’s programs and provides recommendations for needed activities in the area of medicine and research in cardiovascular disease. Dr. Moore is Chair of the Membership and Communications Committee, Vice-Chair of the Early Career Committee, and is the Editor of the ATVB Council Connections newsletter.

Click here for Dr. Moore's CV
 

Research Fellows

 
Jacqueline Alvarez-Leite

Education MD, PhD
Interests Mechanisms of atherosclerosis

My research focuses on the cellular and molecular mechanisms of atherosclerosis. When I am not in Boston, I am an Associate Professor in the Biochemistry and Immunology Department of the Universidade Federal de Minas Gerais, Brazil.

 

Janine van Gils

Education PhD, Sanquin Research, University of Amsterdam (the Netherlands)
Interests Endothelial-leukocyte interactions, transendothelial migration

My research focuses on the effect of netrin-1 and other axonal guidance molecules in leukocyte transendothelial migration and retention under the endothelium. I make use of in vitro models as well as atherosclerosis-prone mice to understand their role in atherogenesis and chronic inflammation.

 
Paula Martin-Fuentes

Education PhD, Zaragoza University, Spain
Interests Mechanisms of atherosclerosis and macrophage biology

I am working on the design and conduct of experiments to understand the molecular mechanisms and consequences of CD36/Toll-like receptor signalling in atherosclerosis.

 
Katey Rayner

Education BSc, U. of Toronto; PhD, University of Ottowa
Interests Cholesterol metabolism

My research focuses on macrophage foam cell formation and inflammation, and the gene regulation networks that contribute to these processes. My time away from the lab is mostly spent watching hockey (my beloved Ottawa Senators) and enjoying the outdoors.

 
Kim Wilkinson

Education PhD, University of Edinburgh, UK
Interests: Receptor-mediated signaling in myeloid cells

My research investigates the molecular mechanisms of CD36 signaling in macrophages and microglia. CD36 recognizes endogenous modified ligands, such as oxidized low-density lipoprotein and ß-amyloid peptide, as well as apoptotic cells and microbial ligands. I am using mutational and proteomic approaches to understand how CD36 cooperates with other pattern recognition receptors to appropriately direct a non-inflammatory or pro-inflammatory host response.

 
Laboratory Technician
 
Alistair Rayner

Education BSc, Queen's University
Interests The immune system and atherosclerosis

My research focuses on identifying the innate immune signaling pathways that promote inflammation in Alzheimer’s disease and atherosclerosis.

 

Graduate Student

 
Luciana Rodrigues Fernandes

Education MSc, Federal University of Minas Gerais, Belo Horizonte, Brasil
Interests Effect of host-parasite interactions on atherosclerosis

My research focuses on the effect of the parasite Toxoplasma gondii on the development and progression of atherosclerosis. I am a PhD candidate in the Biochemistry and Immunology Department of the Universidade Federal de Minas Gerais, Brazil.

 
Former Lab Members
 
Jennifer Tobin    
Cameron Stewart, PhD 2006-08 CSIRO, Geelong, Australia
Merran Stewart, PhD 2006-08 On sabbatical
Julie Goss 2006-07 Project Manager, Monogram Biosciences
Susan Bell, MSc 2005-07 Dietician, U. Massachusetts Medical Center
Marc Laberge, MD  2004-07 Medical Resident, Univ of California San Francisco
Maia Sharuk 2005-06 Medical Student, U. of Massachusetts Medical School
Jiusheng Deng, PhD 2004-05 Post-doctoral Fellow, Emory University, GA
Anita Tseng 2003-05 Medical Student, U. of Massachusetts Medical School
Jessica Silver 2003-05 Ph.D. candidate, University of Washington
Tayeba Khan  2001-03 Ph.D. candidate, Albert Einstein College of Medicine, NY






















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