Welcome to the Kathryn J. Moore Laboratory

Dr. Moore’s research program focuses on identifying the cellular signaling pathways that promote chronic inflammation in atherosclerosis and Alzheimer’s disease, in particular pattern recognition receptors such as the scavenger and Toll-like receptors. These receptors of the innate immune system allow cells to sense local tissue damage or microbial invasion and are critical to the proper regulation of inflammatory responses in health and disease.

Using in vitro and in vivo approaches, she hopes to identify new therapeutic strategies to redirect ongoing immune responses in two important human diseases associated with aging, atherosclerosis and Alzheimer’s disease. This work has received extramural funding from the NIH, the American Heart Association, the Ellison Medical Foundation and the American Health Assistance Foundation.

Opportunities

Post-doctoral positions are available to study the role of CD36-TLR signaling in atherosclerosis and Alzheimer’s disease.

Interested candidates should send a cover letter, CV, and letters of reference to:

Kathryn J Moore, PhD
Massachusetts General Hospital
Lipid Metabolism Unit
55 Fruit Street, GRJ1328
Boston, MA 02114