Penelope Roberts: Unfortunately, we can't say to a parent that the child will be affected in the same manner as you. We've seen people who have the same mutation, but in different families, and very differently affected. We've seen people in the same family, the same mutation, and very differently affected. So, unfortunately, when someone with tuberous sclerosis is considering a pregnancy or having a child, we can't reassure them and say, you know, they won't, they'll be seizure free, or that they'll be just like you because you're bringing in another person's genetic material also. And how those genes will interact with that person's genes. There's a lot that goes on to make a person a person. And so there's no guarantee that a person who was mildly affected, will have a mildly affected child.
© 2006 The General Hospital Corporation.