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Dr. Elizabeth A. Thiele

Elizabeth A. Thiele, MD, PhD
Neurologist


Dr. Elizabeth Thiele: Seizures are very common in tuberous sclerosis. And they're probably the most common medical disorder, or medical problem people with TSC face. We think about 80 to 90 percent of individuals with TSC will have epilepsy at some point in their life. The majority of times, it has its onset in early childhood, about 70 percent of individuals with TSC will develop seizures within their first year of life. And about a third of children with tuberous sclerosis will develop the type of seizures in early childhood or infancy called infantile spasms. Infantile spasms is a very serious seizure disorder that babies can have for a variety of reasons. And, if children do develop infantile spasms, they have a very high risk of very significant developmental impairment. So we follow young children very closely that have TSC, looking to see if they do develop any behaviors that are suggestive of infantile spasms.

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