Lymphangioleiomyomatosis (LAM)

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Lymphangioleiomyomatosis is a degenerative disease of the lungs that involves the proliferation of the LAM cell within the lung. As the name suggests, lymphangioleiomyomatosis is caused by the excessive growth (matosis) of abnormal smooth muscle-like cells (leiomyo), also called LAM cells, around the bronchial tubes, blood vessels (angio), and lymphatic vessels (lymph) of the lung. LAM is a progressive lung disease that affects primarily women and occurs much more frequently in people with TSC than in the general population.