Richard A. Hodin, M.D.
Surgical Director of MGH Crohn's & Colitis Center
Chief of Endocrine Surgery
Division of General Surgery
15 Parkman Street, WANG (WACC) 460
Boston, MA 02114
rhodin@partners.org
phone: (617) 724-2570
fax: (617) 724-2574

Mass General / North Shore Center for Outpatient Care
104 Endicott St. Suite 200
Danvers, MA 01923
(978) 882-6883 Tel.
(978) 882-6864

Clinical Background:

MD Degree:
Tulane University School of Medicine

Residency:
Beth Israel Hospital, Boston, MA
Surgery

Fellowship:
Harvard Medical School, Boston, MA
Post-Doctoral Research Fellow, Division of Genetics, Brigham and Women's Hospital, Harvard Medical School, Boston, MA

Board of Certifications:
American Board of Surgery

Clinical Interests:
Gastrointestinal and Endocrine Surgery, Surgery for Inflammatory Bowel Disease, Laparoscopic Surgery and Colorectal Surgery

Research Interests:
Molecular mechanisms of intestinal epithelial growth and differentiation
Cell cycle regulation and colon carcinogenesis
Thyroid hormone regulation of gut development

Professional Societies:
Fellow, American College of Surgeons
American Surgical Association
Society of University Surgeons
Society for Surgery of the Alimentary Tract
American Association of Endocrine Surgeons

Recent Publications:

1. Dahia, P.L.M, Ross, K, Wright, M.E, Hayashida, C.Y., Santagata, S, Barontini, M, Kung, A.L, Sanso, G., Powers, J.A, Tischler, A, Hodin, R, Heitritter, S, Moore Jr., F, Dluhy, R., Sosa, J.A., I.T., Ocal, Benn, D.E., Marsh, D.J., Robinson, B.G., Schneider, K., Garber, J, Arum, S.M, Korbonits, M, Grossman, A, Pigny, P, Toledo, S. P. A, Nosé, V, Li, C, Stiles, C.D. A HIF1 regulatory loop links hypoxia and mitochondrial signals in pheochromocytomas. 2005; PLoS Genet (in press)

2. Alkhoury F, Malo MS, Mozumder M, Mostafa G, Hodin RA. Differential regulation of intestinal alkaline phosphatase gene expression by Cdx1 and Cdx2. AJP/Gastro. In Press

3. Grikscheit T, Siddique A, Ochoa E, Srinivasan A, Alsberg E, Hodin RA, Vacanti JP. Tissue engineered small intestine improves recovery after massive small bowel resection. Annals of Surgery, 2004;240:748-754

4. Malo MS, Zhang W, Abedrapo MA, Mozumder M, Pushpakaran P, Siddique A, Henderson JW, and Hodin RA. Thyroid hormone positively regulates the enterocyte differentiation marker intestinal alkaline phosphates gene via an atypical response element. Molecular Endocrinology, 2004;18:1941-1962

5. Partridge SK and Hodin RA. Small bowel adenocarcinoma at a strictureplasty site in a patient with Crohn’s disease. Dis Col Rectum, 2004;47:778-781

6. Hinnebusch B, Siddique A, Henderson JW, Malo MS, Zhang W, Athaide CP, Abedrapo MA, Chen X, Yang V, and Hodin RA. Enterocyte differentiation marker intestinal alkaline phosphatase is a target gene of the gut-enriched krüppel-like factor. Am J Physiol, 2004;286:G23-G30

7. Malo MS, Abedrapo M, Chen A, Mozumder M, Pushpakaran P, Alkhoury F, Zhang W, and Hodin RA. Improved eukaryotic promoter-detection vectors carrying two luciferase reporter genes. Biotechniques 2003;35:1150

8. Siewert B, Raptopoulos V, Liu SI, Hodin RA, Davis RB, and Rosen MP. CT predictors of failed laparoscopic appendectomy. Radiology 2003;229:415-420

9. Siddique A, Ocuin L, Hinnebusch B, Malo MS, Abedrapo MA, Henderson JW, Zhang W, Mozumder M, Yang V, and Hodin RA. Convergence of the thyroid hormone and gut-enriched kruppel-like factor pathways in the context of enterocyte differentiation. J Gastrointest Surg, 2003; 7;1053-1061

10. Hinnebusch, B, Henderson JW, Siddique A, Malo MS, Zhang W, Abedrapo MA, and Hodin RA. Transcriptional activation of the enterocyte differentiation marker intestinal alkaline phosphatase is associtaed with changes in the acetylation state of histone H3 at a specific site within its promoter region in vitro. J Gastrointest Surg 2003:7:237-45

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