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Research Resources

At MGH

Center for Integration of Medicine & Innovative Technology (CIMIT)

http://www.cimit.org/
The mission of CIMIT is to improve patient care by facilitating the collaboration of scientists, engineers, and clinicians to catalyze development of innovative technology, emphasizing minimally invasive diagnosis and therapy. CIMIT is bringing together clinicians at the forefront of medicine, scientists and engineers working at the frontiers of high technology, and industry to focus on solutions to perplexing health care problems.

 

Clinical Research Network (Clinical Trials @ Partners)

http://crnet.mgh.harvard.edu/

This is a resource for clinical investigators, sponsors, patients and others interested in advanced clinical research at Massachusetts General Hospital (MGH), the Brigham and Womens Hospital (BWH), and other Partners HealthCare System institutions. CRnet is produced by the Clinical Research Program and the Laboratory of Computer Science at Massachusetts General Hospital.

 

Clinical Research Program

http://www2.massgeneral.org/crp/mghstaff.html

The MGH Clinical Research Program (CRP) provides support for investigators and study teams, advice and guidance for study participants, and education for all involved in clinical research to insure best clinical research practices.

The CRP supports all clinical research studies, providing staff and/or services to manage your study from beginning to end according to Good Clinical Practice, federal, state, and institutional regulations and guidelines. The CRP can also facilitate survey research, large-scale data set analyses, and submission of big NIH applications.

CRP Services includes:
   » Data management consult
   » Project Design
       • Study design and implementation issues
       • Genetics & genomics
       • Biostatistics
       • Comparative Effectiveness Group
       • Translational Medicine
       • Survey research
   » Protocol Development
       • IRB submission
   » Project Execution
       • Coordinators
   » Project Management
       • Managers

New Tools for the Mass General Clinical Research Community
On Clinical Research Day 2009 the Clinical Research Program launched the following tools for the Mass General Clinical Research Community:

  • Clinical Research Program Education Unit Website: The Clinical Research Program Education Unit has a new website. Here, you can easily search and register for courses, find course recordings and handouts, and join online communities for Clinical Investigators and Study Staff. For more information, please see http://hub.partners.org/crp/

  • K-Club: The K-Club is a new online community focused on advancing careers in clinical research. If you have an award or would like to apply for a K23 (junior faculty) or a K24 (senior faculty) awards, simply click on the communities tab at http://hub.partners.org/crp/ to join.

  • Adverse Event (AE) Notification Tool: With this new tool, auto notifications via pager and email can be set up to alert you/your team when a subject presents to the ED or is admitted to the hospital. This will allow study staff to rapidly and easily gather information about research subjects and AE/SAEs in real time. For more information or to learn how to begin using this tool, please contact Kay Ryan (kryan10@partners.org) or Joe LoPiccolo (jlopiccolo@partners.org) in the Mass General Clinical Research Support Office.
MGH Clinical Research Handbook
http://is.partners.org/crphandbook/
The MGH Clinical Research Handbook is compiled by the staff of the Clinical Research Program, this handbook is intended for the use of Research Coordinators, Investigators, and all members of the research team.

 

Executive Committee on Research (ECOR)

ECOR is the central body in MGH research governance and reports to the MGH President and to the General Executive Committee (GEC). ECOR has responsibility for providing strategic guidance to MGH leadership and MGH Trustees regarding future research growth and priorities within MGH, across Partners, and with affiliated external institutions. It also is responsible for providing faculty guidance on development and management of policies on human subjects, proposal review, animal care, animal studies, communications, graduate education, and research facilities (including research space). Various initiatives and relevant subcommittees are established to carry out these responsibilities.

Membership
Its membership includes two elected representatives elected from each of the three HMS faculty ranks (Assistant Professor, Associate Professor, and Professor), as well as representatives elected from the Chiefs’ Council  and appointed faculty members and senior management, including the MGH President and the MGPO President. The committee meets the second and fourth Monday of the month.

Leadership
The current Chair is Robert Kingston, PhD, (Chief of Molecular Biology); the Vice Chair is David N. Louis, MD (Chief of Pathology); and the Past Chair is Daniel Haber, MD, PhD (Director of the MGH Cancer Center). Each position is a three year term; the vice chair usually succeeds to the roles of Chair and Past Chair, thereby assuring continuity over a 9-year time period. These three people, the Sr. Vice President for Research, the Chiefs of Surgery and Medicine, and the Director of the Clinical Research Program, along with the Director of ECOR, form the ECOR Executive Committee.

Research Council and MGH Faculty Meetings
The Research Council, sponsored by ECOR, meets monthly as a town meeting of the MGH investigator community and is open to the entire research community. The ECOR elected representatives serve as the Executive Committee and the Research Council chair and co-chair are the two full-professor elected representatives to ECOR. The goal of these meetings is to provide communication between ECOR and the investigator community and to bring important issues and resources to the attention of the research community.

Recently, the elected representatives have instituted Faculty meetings to offer an opportunity for faculty to discuss shared concerns. The plan is to hold these meetings three times per year (in lieu of Research Council in any given month).

Faculty Representatives
ECOR representatives are able to speak to your interests and concerns in discussions and planning for research at MGH. Representatives are expected to: attend ECOR meetings, attend Research Council meetings, serve on the ECOR Council and meet formally with members of the research community as needed. There are a total of six elected members, two from each faculty rank (Professor, Associate Professor and Assistant Professor). Elected representatives serve a 3-year term. To ensure a balance of continuity and renewal, their terms are staggered so that two seats are up for election every year.

The current Elected Faculty Representatives are:
   » Sylvie Breton, PhD, Professor (elected while Associate Professor)
   » Henry M. Kronenberg, MD, Professor
   » Alice Shaw, MD, PhD, Assistant Professor
   » Susan A. Slaugenhaupt, PhD, Associate Professor
   » Lynda Stuart, MBBS, PhD, Assistant Professor
   » Rudolph E. Tanzi, PhD, Professor

 

Massachusetts General Physicians Organization (MGPO)

http://is.partners.org/mgpoOnline/index.asp
The MGPO is a multi-specialty medical group dedicated to excellence and innovation in patient care, teaching and research. To enhance physician efforts, the MGPO is committed to developing and maintaining an excellent management infrastructure including medical management, managed care contracting, billing and finance, customer service, human resources, information systems and marketing. The physicians of the MGPO are committed to providing medical leadership to the MGH and to working in partnership with the management and staff of the MGH toward the mutual success of both organizations.

 

Medical Research Education for Researchers

http://www.partners.org/Medical-Research/Education-for-Researchers.aspx
Various education opportunities are available to researchers through Partners affiliates, including:
   •Brigham and Women’s Center for Clinical Investigation
   •Massachusetts General Hospital Clinical Research Program
   •Harvard Medical Community Events Calendar

 

MGH Biostatistics Center

http://hedwig.mgh.harvard.edu/biostatistics/groups
The MGH Biostatistics Center supports MGH Investigators undertaking basic research projects. Drawing on a team of highly-skilled biostatisticians, the Biostatistics Center offers consultations and expertise on a range of relevant areas to researchers as they launch new translational and basic research projects including Grant submission/resubmission; Design for non-grant projects and feasibility consultations; Education on a statistical topic; Analysis planning and advice; Assistance with response to a manuscript/journal review.

Consulting for basic science projects is sponsored by ECOR, and can be accessed by contacting Dr. Dianne Finkelstein, Director of Biostatistics

 

MGH Clinical Research Center

http://www2.massgeneral.org/crc/index.htm
The goal of the MGH Clinical Research Center is to provide a clinical laboratory and other support for medical scientists who conduct human subject research. Investigations include studies of normal and abnormal human physiology and studies of the cause, prevention, control and cure of diseases that afflict individuals of all ages, races and ethnic backgrounds

*Also known as The Mallinckrodt Clinical Research Center

 

Partners Core Facilities

http://www.partners.org/researchcores/home.asp

The shared interdepartmental facilities at Partners bring state-of-the-art instrumentation, methodologies and expertise crucial to the promotion of research at Partners. The Partners cores not only provide high quality, cutting edge research services by in-house experts but also constitute a major educational resource for growing research enterprise.

The development of shared resources is part of the Partners cores commitment to interdisciplinary research and will be an important part of future endeavors. Cores make it possible to share wealth of expertise, facilities and equipment with the research community, allow for more efficient use of resources, promote collaboration among investigators and further enhance the competitiveness of Partners investigators to secure research funding.

 

Partners Human Research Committee

http://healthcare.partners.org/phsirb/
The Partners Human Research Committee (PHRC) is the Institutional Review Board (IRB) of Partners Research Management. The PHRC must approve all human-subject research conducted by a Partners-affiliated investigator. Human-subject research is a systematic investigation designed to develop or contribute to generalizable knowledge where an investigator obtains data on individuals either through direct intervention/interaction or through the use of identifiable private information (medical records) or specimens.

 

Partners Human Research Quality Improvement Program

http://www.partners.org/phsqi/
In June 1999, the Human Research Quality Improvement Program (QI Program) was established as part of Partners Human Research Affairs, which oversees human studies conducted at Massachusetts General Hospital (MGH) and Brigham & Women's Hospital (BWH). The goal of this program is to help fulfill the institution's responsibility for ensuring compliance with Federal and State regulations governing human research, and to promote an environment in which human subject research will be conducted according to the highest standards. In doing so, the QI Program has developed and implemented various quality assurance and improvement initiatives to serve the Partners clinical research community.

 

Partners Research Computing

http://rc.partners.org/
Research Computing provides infrastructure, administrative, and translational research support and services to investigators and researchers in the Partners system. The department is organized into five groups: scientific services and infrastructure, genomics IT, specimen banking, RPDR, and research administrative systems. Infrastructure services include:
   » Support and data backup for non-Partners desktops and laptops
   » Help purchasing hardware and software
   » Assistance in solving computing technology problems
   » Secure File Transfer Service

 

Partners Research Management

The Partners Research Management internet was designed with the research community in mind, currently focusing on the administration of grants and contracts and features news and information about the Partners Research Management department. The website covers answers to the following questions:
   » Preparing or submitting a proposal?
   » Managing an award?
   » Collaborating through subcontracts or contracts?
   » Accounting for a grant or contract?

MGH Research Intranet
http://mghresearch.partners.org/
MGH has the largest hospital-based research program in the United States. The MGH Research Intranet brings together many resources that can help investigators, including:
   » Grant funding information
   » Pre- and post-award forms and resources
   » Research policies and procedures
   » Links to many external resources

 

PhD Steering Committee

The PhD Steering Committee is a small group of self-identified MGH-based faculty who share a common interest in enhancing the research environment on our campus with a particular focus on issues unique to people with basic science training working within a clinical department structure. We welcome hearing your comments, concerns and suggestions. For more information about this group, please contact Wilma M. Wasco, PhD or Samuel D. Rabkin, PhD.

 

Research Space Management Group

http://www2.massgeneral.org/rsmg/
The mission of the RSMG at MGH is to improve the use of research space, fair space allocations, and to support the research community. RSMG is responsible for working with ECOR, Research Management and other MGH leaders to develop and implement space allocation strategies that support overall institutional research objectives. RSMG is responsible for completing annual surveys of research space utilization and for reviewing the results with Department/Center chiefs or Program Directors to anticipate changing space needs and to develop plans for meeting future research space requirements for both new and existing programs.

 

Research Ventures and Licensing

http://rvl.partners.org/

Research Ventures & Licensing (RVL) is a division of Partners HealthCare that coordinates industrial relationships and IP management across Partners HealthCare, Massachusetts General Hospital and Brigham and Women’s Hospital.

RVL is a cohesive, coordinated group servicing medical inventors, thought-leaders, entrepreneurs and industry. Our goal is to take medical inventions and innovations discovered by Partners HealthCare researchers and provide the appropriate support and infrastructure to allow technology development, commercialization and, ultimately, the development of products to benefit patients.

The team has backgrounds in technology licensing, patenting, bench research, finance, funding, business, law and start-ups.

Primary functions in converting invention to innovation:
   » Manage inventions arising from research
   » Protect intellectual property
   » Determine commercialization pathway
   » Find industry partners and licensees
   » Identify technology funding options
   » Create marketing plans
   » Support PHS academic-industry alliances

RVL Educational Resources

» Articles and Book Chapters: published articles from RVL and entity staff

» On-line Learning Modules: on-line learning modules provided to support your    discovery of how the commercialization process works. Modules include:
   • Do you have an idea? The invention process
   • Patents
   • Technology Commercialization
   • Clinical Trials and the Food and Drug Administration

Invention Liaison Program
http://rvl.partners.org/resource_center/ilp
The Invention Liaison Program (ILP) is an educational initiative for the research and clinical community at BWH and MGH. The program provides a small network of faculty, the ILP Liaisons, who work with the Research and Licensing office to be a peer-to-peer resource to BWH and MGH investigators on aspects of technology commercialization.

The goal of the program is to support innovation in the community by providing guidance to investigators interested in:
   » Evaluation of the inventive aspects of their discoveries
   » The process of protecting intellectual property
   » Guidance on potential commercialization paths for their inventions
   » Understanding issues of technology transfer and working with industry.

 

 

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Center for Faculty Development Office for Women's Careers Office for Research Career Development