Clinical Research Resources
Clinical Research Network (Clinical Trials @ Partners)
This is a resource for clinical investigators, sponsors, patients and others interested in advanced clinical research at Massachusetts General Hospital (MGH), the Brigham and Womens Hospital (BWH), and other Partners HealthCare System institutions. CRnet is produced by the Clinical Research Program and the Laboratory of Computer Science at Massachusetts General Hospital.
Clinical Research Program
The MGH Clinical Research Program (CRP) provides support for investigators and study teams, advice and guidance for study participants, and education for all involved in clinical research to insure best clinical research practices.
The CRP supports all clinical research studies, providing staff and/or services to manage your study from beginning to end according to Good Clinical Practice, federal, state, and institutional regulations and guidelines. The CRP can also facilitate survey research, large-scale data set analyses, and submission of big NIH applications.
CRP Services includes:
» Data management consult
» Project Design
• Study design and implementation issues
• Genetics & genomics
• Comparative Effectiveness Group
• Translational Medicine
• Survey research
» Protocol Development
• IRB submission
» Project Execution
» Project Management
New Tools for the Mass General Clinical Research Community
On Clinical Research Day 2009 the Clinical Research Program launched the following tools for the Mass General Clinical Research Community:
MGH Clinical Research Handbook
- Clinical Research Program Education Unit Website: The Clinical Research Program Education Unit has a new website. Here, you can easily search and register for courses, find course recordings and handouts, and join online communities for Clinical Investigators and Study Staff. For more information, please see http://hub.partners.org/crp/
- K-Club: The K-Club is a new online community focused on advancing careers in clinical research. If you have an award or would like to apply for a K23 (junior faculty) or a K24 (senior faculty) awards, simply click on the communities tab at http://hub.partners.org/crp/ to join.
- Adverse Event (AE) Notification Tool: With this new tool, auto notifications via pager and email can be set up to alert you/your team when a subject presents to the ED or is admitted to the hospital. This will allow study staff to rapidly and easily gather information about research subjects and AE/SAEs in real time. For more information or to learn how to begin using this tool, please contact Kay Ryan (firstname.lastname@example.org) or Joe LoPiccolo (email@example.com) in the Mass General Clinical Research Support Office.
The MGH Clinical Research Handbook is compiled by the staff of the Clinical Research Program, this handbook is intended for the use of Research Coordinators, Investigators, and all members of the research team.
Executive Committee on Teaching and Education (ECOTE)
ECOTE oversees all institutional matters relating to the teaching mission of the MGH and, in con-junction with the Partners Education Committee, is the principal body charged with implementing educational policy for the Hospital. ECOTE also functions as the institution’s Graduate Medical Education Committee (GMEC) for purposes of national and specialty accreditation of physician training programs, in conjunction with the Partners Education Committee (PEC).
ECOTE participates in responsible strategic planning for the educational mission of the MGH, congruent with both the clinical and research missions of the Hospital and the Partners-wide education enterprise, in conjunction with the PEC.
For more information: contact Georgi Bland
Grants.gov is THE single access point for over 1,000 grant programs offered by all Federal grant making agencies. The U.S. Department of Health and Human Services is proud to be the managing partner for Grants.gov, an initiative that is having an unparalleled impact on the grant community. Grants.gov allows organizations to electronically find and apply for more than $400 billion in Federal grants.
Are You Ready for Grants.gov?
This page contains reference information about what you need to do (and not do) to prepare to use Grants.gov at Harvard Medical School. It also includes a list of contact and information about getting technical assistance
Grant Writing Resources
Harvard Medical School provides a list of resources that cover the many aspects and considerations when writing a grant proposal.
Harvard Catalyst / The Harvard Clinical and Translational Science Center
Harvard Catalyst | The Harvard Clinical and Translational Science Center is dedicated to improving human health by enabling collaboration and providing tools, training and technologies to clinical and translational investigators. Founded in May 2008, Harvard Catalyst is a shared enterprise of Harvard University, its ten schools and its eighteen Academic Healthcare Centers (AHC), as well as the Boston College School of Nursing, MIT, Harvard Pilgrim Health Care, and numerous community partners.
Harvard Catalyst is a member of the NIH-funded Clinical and Translational Science Award (CTSA) Consortium, and shares tools, technologies, and best practices with other consortium members locally (i.e., Boston University, Tufts University, University of Massachusetts Medical School) and nationally.
Harvard Catalyst resources are available to all Harvard faculty, regardless of their institutional affiliation or academic degree.
The resources of Harvard Catalyst fall into five broad categories:
» Collaborative resources
» Research resources
» Education resources
» Funding resources
» The Research Navigators
Explore website to learn what Harvard Catalyst can do for you, or use the Pathfinder tool to orient yourself to the spectrum of translational research and the resources available at each stage.
Harvard Catalyst Advanced Curriculum Compendium
The Harvard Catalyst Advanced Curriculum Compendium (ACC) provides clinical investigators with opportunities for continuing education in clinical investigation beyond the introductory level.
Through a searchable online catalog, the Catalyst ACC offers educational opportunities to learn new methods or update existing clinical investigative skills. The compendium consists of lectures, seminars, and courses that target core competencies fundamental to successful clinical investigation.
Medical Research Education for Researchers
Various education opportunities are available to researchers through Partners affiliates, including:
•Brigham and Women’s Center for Clinical Investigation
•Massachusetts General Hospital Clinical Research Program
•Harvard Medical Community Events Calendar
MGH Clinical Research Center
The goal of the MGH Clinical Research Center is to provide a clinical laboratory and other support for medical scientists who conduct human subject research. Investigations include studies of normal and abnormal human physiology and studies of the cause, prevention, control and cure of diseases that afflict individuals of all ages, races and ethnic backgrounds
*Also known as The Mallinckrodt Clinical Research Center
National Institutes of Health (NIH)
Grants and Funding Opportunties
Partners Human Research Committee
The Partners Human Research Committee (PHRC) is the Institutional Review Board (IRB) of Partners Research Management. The PHRC must approve all human-subject research conducted by a Partners-affiliated investigator. Human-subject research is a systematic investigation designed to develop or contribute to generalizable knowledge where an investigator obtains data on individuals either through direct intervention/interaction or through the use of identifiable private information (medical records) or specimens.
Partners Human Research Quality Improvement Program
In June 1999, the Human Research Quality Improvement Program (QI Program) was established as part of Partners Human Research Affairs, which oversees human studies conducted at Massachusetts General Hospital (MGH) and Brigham & Women's Hospital (BWH). The goal of this program is to help fulfill the institution's responsibility for ensuring compliance with Federal and State regulations governing human research, and to promote an environment in which human subject research will be conducted according to the highest standards. In doing so, the QI Program has developed and implemented various quality assurance and improvement initiatives to serve the Partners clinical research community.
Partners Research Computing
Research Computing provides infrastructure, administrative, and translational research support and services to investigators and researchers in the Partners system. The department is organized into five groups: scientific services and infrastructure, genomics IT, specimen banking, RPDR, and research administrative systems. Infrastructure services include:
» Support and data backup for non-Partners desktops and laptops
» Help purchasing hardware and software
» Assistance in solving computing technology problems
» Secure File Transfer Service
Partners Research Management
The Partners Research Management internet was designed with the research community in mind, currently focusing on the administration of grants and contracts and features news and information about the Partners Research Management department. The website covers answers to the following questions:
» Preparing or submitting a proposal?
» Managing an award?
» Collaborating through subcontracts or contracts?
» Accounting for a grant or contract?
MGH Research Intranet
MGH has the largest hospital-based research program in the United States. The MGH Research Intranet brings together many resources that can help investigators, including:
» Grant funding information
» Pre- and post-award forms and resources
» Research policies and procedures
» Links to many external resources