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Research Faculty > Melissa K. Thomas, MD, PhD

Melissa K. Thomas, MD, PhD

MGH Molecular Endocrinology and Diabetes
Assistant Professor of Medicine
Harvard Medical School



Dr. Thomas completed clinical training at MGH in Internal Medicine and in Endocrinology and research training in the laboratories of Jackie Corbin (Vanderbilt) and Joel Habener (Harvard). Currently, Dr. Thomas is a Clinical Assistant in Medicine affiliated with the Molecular Endocrinology and Diabetes Units at Massachusetts General Hospital and an Assistant Professor of Medicine at Harvard Medical School. She is the recipient of several academic awards, including the Howard Hughes Medical Institute Physician Postdoctoral Fellowship Award, the Albert Weinstein Prize in Medicine and the Canby Robinson Society Achievement Award for leadership contributions at Vanderbilt University School of Medicine, and the Phi Kappa Phi Bowl Award for outstanding scholarship and the Hall of Fame Award from the University of Southern Mississippi,

Dr. Thomas is actively involved in health policy development and has served in national leadership positions in the American Medical Association, the Endocrine Society, and the Accreditation Council for Graduate Medical Education.

Dr. Thomas' research program in pancreatic beta-cell biology is targeted toward the development of novel therapies to restore insulin production in patients with diabetes. She discovered Bridge-1, a novel coactivator of insulin gene transcription and a candidate diabetes gene, and identified a new function for the "hedgehog" signaling pathway in regulating insulin production in beta-cells. In addition she developed and characterized several model systems of diabetes resulting from defects in pancreatic beta-cell transcription factors. Dr. Thomas holds multiple patents from research discoveries.

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