Dr. Seed is a Professor of Genetics at Harvard Medical School and a member of the Molecular Biology Department at Massachusetts General Hospital. He is internationally known for numerous discoveries concerning the molecular basis for the immune response as well as for many technical innovations in the methodologies of molecular biology.
Dr. Seed has worked on several research topics related to the control of the expansion and contraction of immune cell populations, including those that regulate the development of autoimmunity. His laboratory is currently studying the molecular apparatus that controls T cell recognition of target cells. The specific pathways under study are those arising from the T cell antigen receptor and other activating receptors, such as those for TNF-alpha and lipopolysaccharide. He has invented or co-invented processes and therapeutic agents presently used to treat diabetes, cancer, and rheumatoid arthritis.
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