2006 Seminars

January 3, 2006
"Viral and host factors subvert innate immune functions in chronic HCV infection"
Gyongyi Szabo, MD. PhD.

January 10, 2006
"The role of JC Virus in the Pathogenesis of Colorectal Cancer"
C. Richard Boland, M.D.

January 17, 2006
"Normalization of Tumor Vasculature: An Emerging Concept in Antiangiogenic Therapy"
Rakesh Jain, Ph.D.

January 24, 2006
"Identification of a novel virus protein that targets B7-1 costimulation"
Justine Mintern, PhD

January 31, 2006
"Modeling colitis, epithelial hyperplasia, and tumor promotion with Citrobacter rodentium in mice"
David Schauer, D.V.M., Ph.D.

February 7, 2006
"Tumor Suppressor Networks in the Pancreas"
Nabeel El-Bardeesy, Ph.D.

February 14, 2006
"Microscale Hepatic Tissue Engineering"
Sangeeta Bhatia, M.D., Ph.D.

February 21, 2006
"Roles of Ets-1 in Th immune responses and inflammation"
I-Cheng Ho. M.D., Ph.D.

February 28, 2006
"Novel Lipid Mediators and Pathways in the Resolution of Inflammation"
Charles N. Serhan, Ph.D.

March 7, 2006
"Effector functions of mucosal IgG in enteric infections"
Lynn Bry, MD, PhD

March 14, 2006
"Cloning and Stem Cells: Interrogating Development and Disease by Nuclear Transplantation"
Kevin Eggan, Ph.D.

March 21, 2006
"Roles of New Pathways in the B7:CD28 family in regulating T cell activation and tolerance"
Arlene Sharpe, M.D., PhD.

March 28, 2006
"Antigen Presentation: CD1 style"
Michael Brenner, MD

April 11, 2006
"Regulation of hepatic lipid metabolism by a START domain"
David Earle Cohen, M.D., Ph.D.

April 18, 2006
"Modeling cancer progression in zebrafish"
Michael A. Pack, M.D.

April 25, 2006
"Helminths induce T regulatory cell circuits and modulate mucosal inflammation"
Joel Weinstock, M.D.

May 2, 2006
"Cloning and Stem Cells: Interrogating Development and Disease by Nuclear Transplantation"
Kevin Eggan, Ph.D.

May 9, 2006
"Hepatitis C virus-specific T-cells and their role in HCV control and pathogenesis"
Georg Lauer, M.D., Ph.D.

May 16, 2006
"Antigen-Specific T Cell Response and Pulmonary Immunity to Mycobacterium tuberculosis"
Samuel M. Behar, M.D., Ph.D.

June 6, 2006
"T Cell Trafficking to the Lung During Allergic Inflammation:  The Ins and Outs"
Benjamin D. Medoff, MD

June 13, 2006
"Analysis of lipid and peptide antigen presentation following microbial infection"
David Hava, Ph.D.

June 27, 2006
"Immunomodulation of bacteria-associated colitis by helminth"
Haining Shi, D.V.M., Ph.D.

July 11, 2006
"Host-Bacterial Immunomodulation Mediates the Critical balance between Health and Disease"
Sarkis Mazmanian, Ph.D.

July 18, 2006
"Synthesis and regulation of glycan molecules of bacteroides spp.: implications for commensalisms"
Laurie Comstock, Ph.D.

July 25, 2006
"Scavenger receptors in innate immunity and inflammation"
Joseph El Khoury, M.D.

September 12, 2006
"TGF-Beta signaling in Stem Cells and Gastrointestinal Cancer"
Lopa Mishra, M.D.

September 19, 2006
"A GAP for ARF6 in cell migration and glucose homeostasis"
Victor Hsu, M.D.

September 26, 2006
"Mechanisms of CD1d-restricted NKT cell activation "
Manfred Brigl, M.D.

October 3, 2006
"EGFR mutations: an insight into molecularly targeted therapy for lung cancer"
Raffaella Sordella, Ph.D.

October 10, 2006
"Let there be light on G protein-coupled receptors"
Jean-Pierre Vilardaga, Ph.D.

October 24, 2006
"Chemical genetic approach to Vibrio cholerae pathogenesis"
Deborah T. Hung, M.D., Ph.D.

October 31, 2006
"Regulation of T cells in autoimmune disease"
David Hafler, M.D.

November 7, 2006
"Transcriptional Regulatory Networks in Embryonic Stem Cells"
Laurie Boyer, Ph.D.

November 14, 2006
"RNA interference through engineered bacteria in vitro and in vivo"
Shuanglin Xiang, M.D., Ph.D.

November 21, 2006
"Control of cell type switching in the opportunistic fungus C. albicans , a GI colonizer and invasive pathogen"
Julia Koehler, M.D.

November 28, 2006
"Signaling events that control the formation, stability and regression of blood vessels"
Andrius Kazlauskas, Ph.D.

December 12, 2006
"Modeling colon cancer in the mouse"
Kevin Haigis, Ph.D.

December 19, 2006
"CK2 in embryonic development and Wnt signaling"
Isabel Dominguez, Ph.D.

2005 Seminars

January 11, 2005
"Role Of Bacterial Fermentation In Gut Inflammation"
Ian Sanderson, MD, MBBS

January 18, 2005
Francis Chan, Ph.D.

February 1, 2005
"Molecular Regulation Of Gut Epithelial Differentiation And Intestinal Metaplasia"
Ramesh A. Shivdasani, MD, PhD

February 15, 2005
"Signal Integration in Dendritic Cells"
Roy Soberman, MD

February 22, 2005
"Toll-like receptor 5 and colonic inflammation"
Sang Hoon Rhee, Ph.D.

March 8, 2005
"Role of galectin-4 in colitis"
Atsushi Mizoguchi, M.D., Ph.D.

March 15, 2005
"Enteropathogenic E. coli: How a non-invasive pathogen causes so much damage"
Gail Hecht, M.D.

April 12, 2005
"Inhibition of Pathologic Inflammation by gp49B1"
Howard R. Katz, PhD

April 19, 2005
"Innate control of adaptive immunity against mucosal viral infection"
Akiko Iwasaki, Ph.D.

May 3, 2005
"Synthetic Triterpenoids -- New Agents with Anti-inflammatory and Cytoprotective Activities"
Michael Sporn, MD

May 10, 2005
"Role of Netrin-1 in regulating inflammation"
Kathryn Moore, PhD

May 24, 2005
"Cryptosporidium-Host Cell Interactions"
Honorine Ward, MD

May 31, 2005
"Pancreatic lymph nodes monitor pancreatic self and gut non-self"
Shannon Turley, PhD

June 14, 2005
"Induction of water movement across renal epithelial cells; new pathways for aquaporin 2/vasopressin receptor signaling"
Dennis Brown,

June 21, 2005
"Colonization of human colonic crypts and gastric glands by mutated stem cells"
Professor Nicholas Wright , MD PhD DSc

July 5, 2005
"Regulatory properties of proteins of the FXYD family"
Claudia Donnet, PhD

July 12, 2005
"Rapid rearrangement of MHC Class II transport in dendritic cells upon maturation"
Marianne Boes, PhD

July 19, 2005
"Tubulogenesis in C. elegans requires the membrane-cytoskeleton linker erm-1"
Verena Göbel, MD

July 26, 2005
"Epithelial cell MIP-3alpha production in normal colon and IBD"
Andrew Keates, PhD

September 6, 2005
"A novel tissue-specific APC in the mouse gut"
Manjunath N. Swamy, , MBBS, M.D.

September 13, 2005
"Engineered Cys2His2 Zinc Finger Proteins"
Keith Joung, MD, PhD

September 27, 2005
"Genetic Analysis of Host Resistance to Infectious Disease"
William Dietrich, Ph.D.

October 4, 2005
"Tracking the tetraspanin molecule CD63 in professional antigen presenting cells using live cell imaging"
Jatin M. Vyas, MD, PhD

October 11, 2005
"Imprinting of gut homing on T and B cells: a general role for gut-associated dendritic cells and retinoids"
J. Rodrigo Mora, MD, PhD

October 18, 2005
"Evolutionarily conserved oligosaccharides induce
Th2-biasing and immune tolerance"
Don Harn, Ph.D.

October 25, 2005
"Cellular signaling of the innate immune system"
Koichi Kobayashi, MD, PhD

November 1, 2005
"A glimpse into the molecular basis for symbiosis between intestinal microbes and the immune system"
Dennis Kasper, M.D.

November 8, 2005
"How cells prevent chromosome loss: Living biophysical measurements of the mitotic checkpoint"
Jagesh Shah, Ph.D.

November 15, 2005
"The intestinal lymphoid follicle-associated epithelium: gateway to the mucosal immune system"
Neutra, Marian, Ph.D.

November 22, 2005
"Colon-directed Delivery of Viral Vectors Using Virus-microbead Conjugates"
Takeshi Sano, Ph.D.

November 29, 2005
"Novel Stem Cell Populations In The Adult Liver"
Darrell Kotton, M.D.

December 6, 2005
"Spatial and temporal behavior of leukocyte integrins during leukocyte locomotion and transmigration: lessons from live cell imaging"
F. William Luscinskas, Ph.D.

December 13, 2005
"Adult stem cell regulation in the Drosophila gastrointestinal tract"
Craig Micchelli, Ph.D.

December 20, 2005
"Human and murine embryonic stem cells"
Niels Geijsen, Ph.D.

2004 Seminars

January 6, 2004
"Non-Epithelial Expression and the Origin of Epithelial Cancers"
Tim Wang, M.D.

January 13, 2004
"Initiation of Immune Responses by Dendritic Cells"
Nir Hacohen, Ph.D.

January 20, 2004
"Prospects for Stem Cell Based Therapies"
David Scadden, M.D.

January 27, 2004
"The Leukotriene B4 Receptor Blt1 Mediates Early Effector T Cell Recruitment"
Andrew Tager, M.D.

February 10, 2004
"Regulating Enterocyte Cytoskeletal Remodeling and Responses to Pathogenic E.coli"
Ira Herman, M.D.

February 17, 2004
"Connecting the Genome to the Cytoplasm - from Mechanism to Intervention"
Pamela Silver, M.D.

February 24, 2004
"Regulation of Mucosal T Cell Mediated Immune Responses by CEACAM1"
Richard Blumberg, M.D.

March 9, 2004
"What Can Yeast Genomics Tell Us About Bacterial Pathogenesis?"
Cammie Lesser, M.D., Ph.D.

March 16, 2004
"KIM-1: an Epithelial Dedifferentiation Marker"
Joseph Bonventre, M.D., Ph.D.

March 23, 2004
"Establishment of an Optimum Acidic Environment for Sperm Maturation and Storage in the Lumen of the Epididymis"
Sylvie Breton, Ph.D.

March 30, 2004
"Possible Role of V-ATPase as a pH-Sensing Protein (PSP): a2-Subunit of V-ATPase Binds and Recruits Coat Components to Endosomes"
Vladimir Marshansky, Ph.D.

April 6, 2004
"Cilia and Epithelial Development in the Zebrafish" Kidney"
Iain Drummond, Ph.D.

April 13, 2004
"The Rules for the Generation of Lymphoid Lineages"
Shiv Pillai, Ph.D., M.D.

April 20, 2004
"Partnership Between CCK and Leptin in the Regulation of Satiety"
Chung Owyang, M.D.

April 27, 2004
"Using Xenopus to Investigate LBK1, The Peutz-Jeghers Kinase"
Jeremy Greene, Ph.D.

May 4, 2004
"Regeneration of Chronically Injured Livers"
Ana Mae Diehl, M.D.

May 25, 2004
"Is There a Role for Endoscopic Therapy in Chronic Pancreatitis Associated with Abdominal Pain"
Charles Wilcox, M.D.

June 1, 2004
"Regulating Enterocyte Cytoskeletal Remodeling and Responses to Pathogenic E.coli"< br/>Ira Herman, M.D.

June 8, 2004
"The Remarkable Tight Junction. from Paracellular Channels to Proteomics"
Daniel Goodenough, Ph.D.

June 15, 2004
"The Retinoblastoma Protein Pathway in Cell Cycle Exit and Cancer"
Philip W. Hinds, Ph.D.

June 29, 2004
"A Budding Problem: The Design Principles in the Establishment of Cell Polarity"
Rong Li, Ph.D.

July 6, 2004
"3D Models of Epithelial Oncogenesis"
Joan Brugge, Ph.D.

July 13, 2004
"Immune Responses to V. cholerae in Bangladesh"
Edward T. Ryan, M.D.

July 20, 2004
"RNAi Screens in Drosophila Cells: Applications to Cell Biology and Signal Transduction Studies"
Norbert Perrimon, Ph.D.