The Biomedical Core program is a central feature of the CSIBD. These Core resources have been developed to accomplish the goals of supporting the research activities of the Center investigators that increase the understanding of IBD and of stimulating new collaborations and interactions between investigators.
Biomedical Cores are organized to complement the research interests of the CSIBD investigators and to promote research in areas of recognized priority in advancing the understanding of IBD.
- The Molecular Biology Core supports studies defining molecular alterations associated with IBD, especially those related to epithelial function and immune regulation.
- The Morphology Core facilitates the provision of sophisticated morphologic correlation with molecular studies that would not otherwise be available to many CSIBD investigators.
- The Immunology Core aims at increasing the effectiveness and interaction of the large number of Center scientists exploring immune function, and at augmenting the power of molecular studies in defining functional features of the immune system.
- The Genetic Animal Model Core facilitates the use of informative animal models of chronic colitis. The development and study of useful animal models in IBD research has long been appreciated as an important priority.
- The Clinical/Tissue Core is a resource for providing carefully collected, catalogued and shared samples from `pedigreed' patients for investigators in this center, thus, facilitating translating research. These samples include tissue and blood (serum and DNA) from IBD patients and controls.
The Biomedical Cores functioning is overseen by the Administrative Core.
