Consider your preliminary study design: What is your hypothesis? How can you improve it?
- Excellent research begins with a clear hypothesis which can be either supported or rejected through the generation and analysis of new data collected via the conduct of clinical research.
- These data should be subjected to statistical analysis, and the results should either confirm or reject the original hypothesis.
- To create a strong hypothesis, start with a good research question -- one for which the answer will matter to other researchers in the field, practicing clinicians, or patients.
- Convert your research question to hypothesis by asserting a position. This will lead directly to a consideration of measures, both of exposure and outcome.
- The null hypothesis is a statement a researcher wants to test. In general, the null hypothesis is the same as a theoretical expectation. Analysis is performed to reject or accept the null hypothesis.
▪ Fundamentals of Clinical Trials
▪ Design and Conduct of Clinical Trials