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Consider your preliminary study design: What is your hypothesis? How can you improve it?

Information:

  • Excellent research begins with a clear hypothesis which can be either supported or rejected through the generation and analysis of new data collected via the conduct of clinical research.
  • These data should be subjected to statistical analysis, and the results should either confirm or reject the original hypothesis.
  • To create a strong hypothesis, start with a good research question -- one for which the answer will matter to other researchers in the field, practicing clinicians, or patients.
  • Convert your research question to hypothesis by asserting a position. This will lead directly to a consideration of measures, both of exposure and outcome.
  • The null hypothesis is a statement a researcher wants to test. In general, the null hypothesis is the same as a theoretical expectation. Analysis is performed to reject or accept the null hypothesis.

Resources:

Consultation with Clinical Research Program (CRP) Faculty

Courses:

ONLINE:
Harvard X's Fundamentals of Clinical Trials

LIVE TRAINING:
Design and Conduct of Clinical Trials

Please click here for a list of CRP current offerings. Many of the CRP's courses are recorded, click here to access our recordings and handouts.