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Principal Investigator Randy Gollub, M.D., Ph.D., Psychiatry
fMRI Investigation of Expectancy on Acupuncture Analgesia
Distinguishing acupuncture from placebo acupuncture has been a methodological challenge. We propose to use a quantitative brain imaging method to investigate the mechanism of acupuncture analgesia, placebo analgesia and their interrelationship. A well tested method to induce high and low expectation will be combined with acupuncture analgesia and sham acupuncture analgesia to create a 2 X 2 comparison of verum acupuncture and sham acupuncture each paired with positive and negative expectancies.

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