Faculty > Jonathan Rosand    
       

Jonathan Rosand, M.D.

Selected Publications

1. Flibotte JJ, Hagan N, O’Donnell J, Greenberg SM, Rosand J. Warfarin, hematoma expansion, and outcome of intracerebral hemorrhage. Neurology. 2004;63(6):1059-64.

2. Fang MC, Chang Y, Hylek EM, Rosand J, Greenberg SM, Go AS, Singer DE. Advanced age, anticoagulation intensity, and risk for intracranial hemorrhage among patients taking warfarin for atrial fibrillation. Ann Intern Med. 2004;141(10):745-52.

 

OVERVIEW
 
LAB MEMBERS
 
PUBLICATIONS

STROKE GENOMICS  


3. Goldstein JN, Thomas SH, Frontiero V, Joseph A, Engel C, Snider R, Smith EE, Greenberg SM, Rosand J. Timing of fresh frozen plasma administration and rapid correction of coagulopathy in warfarin-related intracerebral hemorrhage. Stroke. 2006;37(1):151-5.

4. Rosand J, Bayley N, Rost N, de Bakker PI. Many hypotheses but no replication for the association between PDE4D and stroke. Nat Genet. 2006;38(10):1091-2.

5. Levine JM, Snider R, Finkelstein D, Gurol ME, Chanderraj R, Smith EE, Greenberg SM, Rosand J. Early edema in warfarin-related intracerebral hemorrhage. Neurocrit Care. 2007;7(1):58-63.

6. Goldstein JN, Fazen LE, Snider R, Schwab K, Greenberg SM, Smith EE, Lev MH, Rosand J. Contrast extravasation on CT angiography predicts hematoma expansion in intracerebral hemorrhage. Neurology. 2007; 68(12):889-94.

7. Gudbjartsson DF, Arnar DO, Helgadottir A, Gretarsdottir S, Holm H, Sigurdsson A, Jonasdottir A, Baker A, Thorleifsson G, Kristjansson K, Palsson A, Blondal T, Sulem P, Backman VM, Hardarson GA, Palsdottir E, Helgason A, Sigurjonsdottir R, Sverrisson JT, Kostulas K, Ng MC, Baum L, So WY, Wong KS, Chan JC, Furie KL, Greenberg SM, Sale M, Kelly P, MacRae CA, Smith EE, Rosand J, Hillert J, Ma RC, Ellinor PT, Thorgeirsson G, Gulcher JR, Kong A, Thorsteinsdottir U, Stefansson K. Variants conferring risk of atrial fibrillation on chromosome 4q25. Nature. 2007;448(7151):353-7.

8. Ay H, Arsava EM, Rosand J, Furie KL, Singhal AB, Schaefer PW, Wu O, Gonzalez RG, Koroshetz WJ, Sorensen AG. Severity of Leukoaraiosis and Susceptibility to Infarct Growth in Acute Stroke. Stroke. 2008;39:1409-13.

9. Rost NS, Smith EE, Chang Y, Snider RW, Chanderraj R, Schwab K, FitzMaurice E, Wendell L, Goldstein JN, Greenberg SM, Rosand J. Prediction of Functional Outcome in Patients with Primary Intracerebral Hemorrhage: The FUNC Score. Stroke. 2008;39:2304-09.

10. Eckman MH, Wong LKS, Soo YOY, Lam W, Yan SR, Greenberg SM, Rosand J. Patient-Specific Decision Making for Warfarin Therapy in Nonvalvular Atrial Fibrillation: How Will Screening with Genetics and Imaging Help? Stroke. 2008;39: 3308-3315.

11. Kumar MA, Rost NS, Snider RW, Chanderraj R, Greenberg SM, Smith EE, Rosand J. Anemia and hematoma volume in acute intracerebral hemorrhage. Critical Care Medicine. 2009;37:1442-47.

12. Arsava EM, Rahman R, Rosand J, Lu J, Smith EE, Rost N, Singhal, AB, Lev, MH, Furie, KL, Koroshetz, WJ, Sorensen, AG, Ay H. Severity of Leukoaraiosis Predicts Clinical Outcome after Ischemic Stroke. Neurology 2009; 72(16): 1403-1410.

13. Eckman MH, Rosand J, Greenberg SM, Gage BF. Cost-Effectiveness of Using Pharmacogenetic Information in Warfarin Dosing for Patients With Nonvalvular Atrial Fibrillation. Ann Intern Med 2009;150(2): 73-83.

14. Eckman MH, Greenberg SM, Rosand J. Should we test for CYP2C9 before initiating anticoagulant therapy in patients with atrial fibrillation? J Gen Intern Med 2009;24:543-49.

15. Gschwendtner A, Bevan S, Cole JW, Plourde A, Matarin M, Ross-Adams H, Meitinger T, Wichmann E, Mitchell BD, Furie KL, Slowik A, Rich SS, Syme PD, Macleod MR, Meschia JF, Rosand J, Kittner SJ, Markus H, Müller-Myhsok B, Dichgans M, on behalf of the International Stroke Genetics Consortium. Sequence variants on chromosome 9p21.3 confer risk of atherosclerotic stroke. Ann Neurol. 2009; 65(5): 531-539.

16. Oleinik A, Romero JM, Schwab K, Lev MH, Jhawar N, Delgado-Almondoz JE, Smith EE, Greenberg SM, Rosand J, Goldstein J. CT angiography for intracerebral hemorrhage does not increase risk of acute nephropathy. Stroke 2009; 40(7): 2393-2397.

17. Delgado-Almondoz JE, Yoo AJ, Stone AM, Schaefer PW, Goldstein JN, Rosand J, Oleinik A, Lev MH, Gonzalez RG, Romero JM. Systematic characterization of the CT angiography spot sign in primary intracerebral hemorrhage identifies patients at highest risk for hematoma expansion: The spot sign score. Stroke. 2009; 40(9): p. 2994-3000.

18. Delgado-Almandoz JE, Yoo AJ, Stone AM, Schaefer PW, Oleinik A, Brouwers HB, Goldstein JN, Rosand J, Lev MH, Gonzalez RG, Romero JM. The Spot Sign Score in Primary Intracerebral Hemorrhage Identifies Patients at Highest Risk of In-Hospital Mortality and Poor Outcome Among Survivors. Stroke 2010; 41(1):54-60.

19. Biffi A, Anderson CD, Desikan RS, Sabuncu M, Cortellini L, Schmansky N, Salat D, Rosand J. Sequence Variation Influences Neuroimaging Measures in Alzheimer’s Disease. Archives of Neurology 2010;67:667-85.

20. Anderson CD, Biffi A, Rost NS, Cortellini L, Furie KL, Rosand J. Chromosome 9p21 in Ischemic Stroke: Population Structure and Meta-Analysis. Stroke 2010; 41:1123-1131.

21. The International Stroke Genetics Consortium and the Wellcome Trust Case-Control Consortium 2. Failure to Validate Association between Variants on 12p13 and Ischemic Stroke. New England Journal of Medicine 2010; 362:1547-1550.

22. Biffi A, Anderson CD, Rahman R, Nalls MA, Cortellini L, Rost NS, Plourde A, Sonni A, de Bakker PIW, Ross O, Greenberg SM, Furie KL, Meschia JF, Singleton AB, Saxxena R, Rosand J. Principal-component analysis for assessment of population stratification in mitochondrial medical genetics. American Journal of Human Genetics 2010;86:904-17.

23. Arsava, EM, Ballabio E, Cole J, Delago-Martinez MP, Dichgans M, Fazekas F, Furie KL, Illoh K, Jood K, Kittner S, Lindgren A, Majersik J, Meurer W, Montaner J, Norrving B, Olugbodi AA, Pasdar A, Redfors R, Schmidt R, Sharma R, Singhal AB, Sorensen AG, Sudlow C, Thijs V, Worrall B, Rosand J, Ay H on behalf of the International Stroke Genetics Consortium. The Causative Classification of Stroke System: An International Reliability and Optimization Study. Neurology 2010, in press.

24. Lubitz SA, Sinner MF, Lunetta KL, Makino S, Pfeufer A, Rahman R, Veltman CE, Barnard J, Bis JC, Danik SP, Sonni A, Shea MA, Del Monte F, Perz S, Muller M, Peters A, Greenberg SM, Furie KL, van Noord C, Boerwinkle E, Stricker BH, Witteman J, Smith JD, Chung MK, Heckbert SR, Benjamin EJ, Rosand J, Arking DE, Alonso A, Kaab S, Ellinor PT. Independent susceptibility markers for atrial fibrillation on chromosome 4q25. Circulation 2010, in press.

25. Biffi A, Sonni A, Anderson CD, Kissela B, Jagiella JM, Schmidt H, Jimenez-Conde J, Fernadez-Cadenas I, Cortellini L, Ayres A, Schwab K, Juchniewicz K, Urbanik A, Rost NS, Viswanathan A, Seifert-Held T, Stoegerer EM, Elosua R, Rabionet R, Brown DS, Silliman SL, Selim M, Worrall BB, Meschia JF, Monataner J, Roquer J, Schmidt R, Greenberg SM, Slowik A, Broderick JP, Woo D, Rosand J on behalf of the International Stroke Genetics Consortium. Variants at the APOE locus influence risk of deep and lobar intracerebral hemorrhage. Annals of Neurology 2010, in press.

26. Anderson CD, Nalls MA, Biffi A, Greenberg SM, Singleton AB, Meschia JF, Rosand J. The impact of survival bias on case-control genetic analysis. Circulation 2010, in press.

27. Anderson CD, Biffi A, Rahman R, Ross OA, Jagiella J, Kissela B, Cole JW, Cortellini L, Rost NS, Cheng YC, Greenberg SM, de Bakker PIW, Brown RD, Brott TG, Mitchel BD, Broderick JP, Worrall BB, Furie KL, Kittner SJ, Woo D, Slowik A, Meschia JF, Saxena R, Rosand J on behalf of the International Stroke Genetics Consortium. Common Mitochondrial Sequence Variants in Ischemic Stroke. Annals of Neurology 2010, in press.

28. Rost NS, Fritzpatrick K, Biffi A, Kanakis A, Devan W, Anderson CD, Cortellini L, Furie K, Rosand J. White Matter Hyperintensity Burden and Susceptibility to Cerebral Ischemia. Stroke 2010, in press.

29. Rost NS, Rahman RM, Biffi A, Smith EE, Kanakis A, Fitzpatrick K, Lima F, Worrall BB, Meschia JF, Brown RD, Brott TG, Sorensen AG, Greenberg SM, Furie KL, Rosand J. White Matter Hyperintensity Volume is Increased in Small Vessel Stroke Subtypes. Neurology 2010, in press.

Review/Editorials

1. Rosand J, Altshuler D. Human genome sequence variation and the search for genes influencing stroke [review]. Stroke. 2003;34(10):2512-6.

2. Steiner T, Rosand J, Diringer M. Intracerebral hemorrhage associated with oral anticoagulant therapy: current practices and unresolved questions [review]. Stroke. 2006;37(1):256-62.

3. de Bakker PI, Rosand J. In search of genes for stroke [editorial]. Lancet Neurol. 2007;6(5):383-4.

4. Rost NS, Greenberg SM, Rosand J. Genetic Architecture of Intracerebral Hemorrhage [review]. Stroke. 2008; 39: 2166.

5. The Genes for Cerebral Hemorrhage on Anticoagulation Collaborative Group. Exploiting Common Genetic Variation to Make Anticoagulation Safer [review]. Stroke 2009; 40(S64-S66).

6. Anderson CD, Biffi A, Greenberg SM, Rosand J. Personalized approaches to clopidogrel therapy: Are we there yet? [review]. Stroke 2010, in press.

  
       
 
Copyright © 2006 Massachusetts General Hospital. All Rights Reserved.