Allan F. Moore, M.D., a fellow
in the Massachusetts General Hospital Endocrine
Division and a physician in Internal Medicine,
died July 24, 2008 from injuries he sustained
in a motor vehicle accident. He was 31 years
old.
Dr. Moore graduated with high
honors from the University of Virginia in 1999
and received his medical degree from Vanderbilt
University School of Medicine in 2003, joining
the MGH that same year as a resident in Internal
Medicine. At the time of his death Moore was
conducting research into the genetic basis of
type 2 diabetes and –a gifted scholar
–was also pursuing a master’s degree
in medical science at Harvard Medical School.
Extremely dedicated to the hospital community,
Moore was instrumental in the founding and organizing
of the MGH Blood Donor Center’s annual
Medical Service Blood Drive Challenge, which
celebrated its fourth year in May.
Dr. Moore is survived by his wife,
Rebekah Gee, M.D., a former MGH resident who
was also injured in the accident and is recovering;
his father, Michael Moore, M.D.; his mother,
Janet; his brother and sister-in-law, David
and Lisa Moore; his paternal grandmother, Ruby
M. Moore; and his father-in-law, E. Gordon Gee,
J.D., Ed.D.
Dr. Moore had a brief but prolific
academic career. His publications are listed
below:
• ORIGINAL RESEARCH
Moore AF, Jablonski KA, Mason CC, McAteer JB,
Arakaki RF, Goldstein BJ, Kahn SE, Kitabchi
AE, Hanson RL, Knowler WC, Florez JC for the
Diabetes Prevention Program Research Group.
The association of ENPP1 K121Q with diabetes
incidence is abolished by lifestyle modification
in the Diabetes Prevention Program. J Clin Endocrinol
Metab 2008 [Epub ahead of print].
Moore AF, Jablonski KA, McAteer JB, Saxena R,
Pollin TI, Franks PW, Hanson RL, Shuldiner AR,
Knowler WC, Altshuler D, Florez JC for the Diabetes
Prevention Program Research Group. Extension
of type 2 diabetes genome-wide association scan
results in the Diabetes Prevention Program.
Diabetes 2008;57:2503-2510.
Moore AF, Heiderstadt NT, Huang E, Howell NH,
Wang Z, Siragy HM, Carey RM. Selective inhibition
of the renal angiotensin type 2 receptor increases
blood pressure in conscious rats. Hypertension
2001;37:1285-1291.
Ozono R, Matsumoto T, Shingu T, Oshima T, Teranishi
Y, Kambe M, Matsuura H, Kajiyama G, Wang Z,
Moore AF, Carey RM. Expression and localization
of angiotensin subtype receptor proteins in
the hypertensive rat heart. Am J Physiol Regulatory
Integrative Comp Physiol 2000;278:R781-R789.
Wang Z, Moore AF, Ozono R, Siragy HM, Carey
RM. Immunolocalization of subtype-2 angiotensin
II (AT2) receptor protein in rat heart. Hypertension
1998;32:78-83.
Ozono R, O’Connell DP, Moore AF, Wang
Z, Sanada H, Felder RA, Carey RM. Localization
of the dopamine D1 receptor protein in the human
heart and kidney. Hypertension 1997;30:725-729.
Ozono R, Wang Z, Moore AF, Inagami T, Siragy
HM, Carey RM. Expression of the subtype-2 angiotensin
(AT2) receptor protein in rat kidney. Hypertension
1997;30:1238-1246.
Smith MA and Moore AF. Eastern European public
health: opportunity and challenge. Virginia
Medical Quarterly 1995;122:230-232.
• REVIEWS
Moore AF and Florez JC. Genetic susceptibility
to type 2 diabetes and implications for antidiabetic
therapy. Annual Reviews of Medicine 2008;59:43-59.
• CASE REPORTS
Moore AF, Abourizk NN. Necrobiosis lipoidica:
an important cutaneous manifestation of diabetes
that may respond to antiplatelet therapy. Endocr
Pract. 2008;14:947-948.
Moore AF, Wexler TL, Yung RL, Kish J, Larvie
M, Lauter K, Arnold A, Finkelstein JS, Burnett-Bowie
SA. An unusual case of primary hyperparathyroidism
with profoundly elevated parathyroid hormone
levels. Endocr Pract. 2008;14:892-897.
Moore AF, Soper T, Jones N, Grevelink J, Abourizk
N. Psoriatic exacerbation associated with insulin
therapy. Diabetes Care 2008;31:e31.
Faris J, Moore AF, Daniels G. Sunitinib (Sutent)-induced
thyrotoxicosis due to destructive thyroiditis:
A case report. Thyroid 2007;17:1147-1149.
Moore AF and Grinspoon S. A dural tale. Journal
of Clinical Endocrinology and Metabolism. 2007;92:3367-3368.
Moore A, Lau E, Yang C, Mackool B, Kuter D.
Dalteparin-induced skin necrosis in a patient
with metastatic lung adenocarcinoma. American
Journal of Clinical Oncology 2007;30:329-331.
Moore AF, Zhu H, Bazari H. Diarrhea and a sore
shoulder. Infectious Diseases in Clinical Practice
2005; 13:1-2.
Moore AF, Pukkila-Worley R, Dec GW. Asymmetric
ST-segment elevations in meningococcal meningitis.
Hospital Physician 2005; 41:25-27.