CeDAR Symposium

VITAMIN D AND CARDIOVASCULAR DISEASE

October 17-18, 2008

Day 1: Friday October 17, 2008

7:30-8:00 AM   CONTINENTAL BREAKFAST

8:00-8:15 AM   Introduction / Welcome

Ravi Thadhani – Harvard

8:15-8:45 AM   Vitamin D deficiency and CVD outcomes: The epidemiologic evidence

Erin Michos – Johns Hopkins

8:55-9:20 PM   Clinical trials of vitamin D and CVD outcomes in the general population

Carlos Camargo – Harvard

Robert Scragg – University of Auckland, New Zealand

9:30-10:00 AM   Genomic and non-genomic actions of vitamin D

Anthony Norman – UC Riverside

10:15-10:30 AM   BREAK

10:30-10:55 AM   Stalking the VDR: Vitamin D’s effects on cardiac contractility, hypertrophy, fibrosis and blood pressure

Robert Simpson – University of Michigan

11:05-11:25 AM   Overview of endothelium-derived contracting factor

Paul Vanhoutte – University of Hong Kong

11:25-11:35 AM   Vitamin D 3 reduces endothelium-dependent contraction in the aorta of the spontaneously hypertensive rat

Michael Wong – University of Hong Kong

11:45-12:45 PM   LUNCH

12:45-1:10 PM   Vitamin D, the renin-angiotensin system, and cardiac hypertrophy: Causal or correlates?

Yan Li – University of Chicago

1:20-1:40 PM   Vitamin D action in the heart and vasculature

David Gardner – UCSF

1:50-2:10 PM   Cardiac hypertrophy and rescue in the 1-alpha hydroxylase KO model

David Goltzman – McGill University

2:20-2:40 PM   Cardio-renal effects of vitamin D

Eduardo Slatopolsky – Washington University

2:40-3:00 PM   Renal and vascular axis in kidney disease

Adriana Dusso – Washington University

3:15-3:30 PM   BREAK

3:30-3:45 PM Cardiac hypertrophy: Planning clinical trials

Ravi Thadhani – Harvard

3:55-4:15 PM   Vitamin D status and under-represented minorities

Sherri Ann Burnett-Bowie – Harvard

4:15-4:35 PM   CVD and CKD in under-represented minorities

Keith Norris – UCLA

4:50-5:00 PM   Wrap-up / Announcements

5:00-6:30 PM   BREAK

6:30 PM   DINNER AT THE MUSEUM OF SCIENCE ( www.mos.org)

7:00 PM   Dinner Speaker: Michael Holick – Boston University

Day 2: Saturday October 18, 2008

7:30-8:00 AM   CONTINENTAL BREAKFAST

8:00-8:20 AM   Vitamin D and macrophage function

Martin Hewison – UCLA

8:30-8:50 AM   Vitamin D and inflammation

Chantal Mathieu – University of Leuven, Belgium

9:00-9:20 AM   Vitamin D, metabolism, and CVD

Alp Ikizler – Vanderbilt

9:30-9:50 AM   Fibroblast growth factor-23 in chronic kidney disease

Myles Wolf – University of Miami

10:00-10:15 AM   BREAK

10:15-10:45 AM   Vitamin D in heart failure

Armin Zittermann – Heart Center NRW, Germany

10:55-11:20 PM   Is there “room” for vitamin D among CVD therapies?

Thomas Wang – Framingham Heart Study

11:20-12:00 AM   Discussion / Next steps

Carlos Camargo – Harvard

Erin Michos – Johns Hopkins

Ravi Thadhani – Harvard

12:00 PM   Adjourn