 For Appointments
617-724-4000
Office Address
Massachusetts General Hospital Cancer Center
Tucker Gosnell Center for Gastrointestinal Cancers
55 Fruit Street, YAW 7
Boston, MA 02114
Clinical Interests
Gastrointestinal Malignancies; Gastrointestinal Cancer Genetics; Phase I Clinical Trials
Education
PhD Degree: Stanford University, Stanford, CA, 1995
MD Degree: Duke University, Durham, NC, 1996
Postdoctoral Training
Residency: Hematology & Oncology, Brigham and Women's Hospital, Boston, MA
Fellowship: Hematology & Oncology, Dana-Farber/Partners CancerCare, Boston, MA
Board Certification
Internal Medicine, 2001
Medical Oncology, 2003
Academic Appointments
Assistant in Medicine
My Publications
Link to PubMed Database
Selected Publications
Fleming, J.E., Kwak, E.L. In Vitro Translation Products of Drosophila Mitochondria are Contaminated with Newly Synthesized Bacterial Proteins. Biochemical and Biophysical Research Communications 1986; 136, 797-801.
Torti, S.V., Kwak, E.L., Miller, L.L., Ringold, G.M., Myambo, K.B., Young, A.P., Torti, F.M. The Molecular Cloning and Characterization of Murine Ferritin Heavy Chain, a Tumor Necrosis Factor-Inducible Gene. Journal of Biological Chemistry 1988; 263, 12638-12644.
Kwak, E.L., Torti, S.V., Torti, F.M. Murine Ferritin Heavy Chain: Isolation and Characterization of a Functional Gene. Gene 1990; 94, 255-261.
Tsuji, Y., Kwak E.L., Saika, T., Torti, S.V., Torti, F.M. Preferential Repression of the H Subunit of Ferritin by Adenovirus E1A in NIH3T3 Mouse Fibroblasts. Journal of Biological Chemistry 1993; 268, 7270-7275.
Kwak, E.L., Larochelle, D.A., Beaumont, C., Torti, S.V., Torti, F.M. Role for NF-kB in the Regulation of Ferritin H by Tumor Necrosis Factor-a. Journal of Biological Chemistry 1995; 270, 15285-15293.
Kwak, E.L., Gerald, H., Larochelle, D.A., Vithalani, K.K., Niswonger, M., Maready, M., De Lozanne, A. LvsA, A Protein Related to the Mouse Beige Protein, Is Required for Cytokinesis in Dictyostelium. Molecular Biology of the Cell 1998; 10, 4429-4439.
Kwak, E.L., Moberg, K.H., Wahrer, D.C., Quinn, J.E., Gilmore, P.M., Graham, C.A., Hariharan, I.K., Harkin, D.P., Haber, D.A., Bell, D.W. Infrequent mutations of Archipelago (hAGO, hCDC4, Fbw7) in primary ovarian cancer. Gynecologic Oncology 2005; 98, 124-128.
Kwak, E.L., Sordella, R., Bell, D.W., Godin-Heymann, N., Okimoto, R.A., Brannigan, B.W., Harris, P.L., Driscoll, D.R., Fidias, P., Lynch, T.J., Rabindran, S.K., McGinnis, J.P., Wissner, A., Sharma, S.V., Isselbacher, K.J., Settleman, J., Haber, D.A. Irreversible inhibitors of the EGF receptor may circumvent acquired resistance to gefitinib. Proceedings of the National Academy of Sciences, USA 2005; 102, 7665-7670.
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