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Pediatric Clinical Trials
Trials for Brain Tumors Trials for Sarcomas
Trials for Leukemia/Lymphoma Trials for Other Solid Tumors

Clinical Trials - Brain Tumors
 
  MEDULLOBLASTOMA
 
    For Information:   617-724-1836
     
 
    Protocol #:   MGH 99-271 Medullo
    Investigator:   Nancy J. Tarbell, MD
    Description:   Proton Therapy for Medulloblastoma and Other CNS Tumors –
A Prospective Look at Acute and Long-Term Sequelae
 
    For Information:   617-724-0857
 
    Protocol #:   COG ACNS0331
    Investigator:   David H. Ebb, MD
    Description:   Standard Risk Medulloblastoma
   
    For Information:   617-724-0857
   
    Protocol #:   COG ACNS0332
    Investigator:   David H. Ebb, MD
    Description:   Carboplatin with Radiation Therapy and Isotretinoin for Other than Average Risk Medulloblastoma/PNET
   
    For Information:   617-724-0857
   
    Protocol #:   PBTC-016
    Investigator:   David H. Ebb, MD
    Description:   Lapatinib for Recurrent or Refractory Medulloblastoma
   
  EPENDYMOMA
         
    For Information:   617-724-0857
         
    Protocol #:   PBTC-016
    Investigator:   David H. Ebb, MD
    Description:   Lapatinib for Recurrent or Refractory Ependymoma
 
  BRAIN STEM Tumors or GLIOMAS
 
    For Information:   617-724-0857
 
    Protocol #:   COG ACNS0222
    Investigator:   David H. Ebb, MD
    Description:  

Motexafin-Gadolinium and Radiation Therapy for the Treatment of Pontine Glioma

 
    For Information   617-724-0857
 
    Protocol #:   PBTC 014
    Investigator:   David H. Ebb, MD
    Description:  

Zarnestra and XRT in Newly Diagnosed Brainstem Glioma

 
    For Information   617-724-0857
 
    Protocol #:   PBTC 015
    Investigator:   David H. Ebb, MD
    Description:  

O6-Benzylguanine and Temozolomide in Recurrent or Progressive High-Grade Gliomas or Brain Stem Gliomas

 
    For Information   617-724-0857
 
    Protocol #:   PBTC 016
    Investigator:   David H. Ebb, MD
    Description:  

Lapatinib for Recurrent or Refractory Glioma

 
    For Information   617-724-0857
 
    Protocol #:   PBTC 021
    Investigator:   David H. Ebb, MD
    Description:  

Capecitabine and Radiation Therapy in Newly Diagnosed Brainstem and High Grade Gliomas

 
    For Information   617-724-0857
         
    Protocol #:   PBTC 022
    Investigator:   David H. Ebb, MD
    Description:  

Bevacizumab and Irinotecan in Recurrent, Progressive or Refractory Malignant Gliomas and Diffuse/Intrinsic Brain Stem Gliomas

 
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  BRAIN TUMORS - RECURRENT OR PROGRESSIVE
 
    For Information   617-724-0857
 
    Protocol #:   PBTC 015
    Investigator:   David H. Ebb, MD
    Description:  

O6-Benzylguanine and Temozolomide in Recurrent or Progressive High-Grade Gliomas or Brain Stem Gliomas

 
    For Information:   617-724-0857
 
    Protocol #:   PBTC 016
    Investigator:   David H. Ebb, MD
    Description:   Lapatinib in Recurrent or Refractory Medulloblastoma, Malignant Glioma or Ependymoma
 
    For Information:   617-724-0857
         
    Protocol #:   PBTC 018
    Investigator:   David H. Ebb, MD
    Description:   Lenalidomide Recurrent or Refractory Primary CNS Tumors
 
    For Information:   617-724-0857
 
    Protocol #:   PBTC 020
    Investigator:   David H. Ebb, MD
    Description:   AZD2171 in Recurrent or Progressive Central Nervous System (CNS) Tumors
 
    For Information:   617-724-0857
 
    Protocol #:   PBTC 022
    Investigator:   David H. Ebb, MD
    Description:   Bevacizumab and Irinotecan in Recurrent, Progressive or Refractory Malignant Gliomas and Diffuse/Intrinsic Brain Stem Gliomas
 
    For Information:   617-724-0857
         
    Protocol #:   PBTC 023
    Investigator:   David H. Ebb, MD
    Description:   Enzastaurin in Refractory Primary CNS Tumors
 
  CNS GERMINOMA
 
    For Information:   617-724-0857
 
    Protocol #:   COG ACNS0232
    Investigator:   David H. Ebb, MD
    Description:   Radiation Therapy vs Chemotherapy Followed by Radiotherapy for Newly Diagnosed Primary CNS Germinoma
 
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Trials for Pediatric Leukemia/Lymphoma
 
  LEUKEMIA – Precursor B Cell
 
    For Information:   617-724-0857
 
    Protocol #:   COG AALL0331
    Investigator:   Alison M. Friedmann, MD
    Description:   Standard-Risk Acute Lymphoblastic Leukemia (ALL)
 
    For Information:   617-724-0857
         
    Protocol #:   COG AALL0232
    Investigator:   Alison M. Friedmann, MD
    Description:   High-Risk Acute Lymphoblastic Leukemia (ALL)
 
    For Information:   617-724-0857
 
    Protocol #:   COG AAML0531
    Investigator:   Howard Weinstein , MD
    Description:   Newly Diagnosed Acute Myelogenous Leukemia (AML)
 
  HODGKIN DISEASE
 
    For Information:   617-724-0857
 
    Protocol #:   HOD99
    Investigator:   Howard J. Weinstein, MD
    Description:   Risk-Adapted Therapy in Pediatric Hodgkin Disease (Low Risk and High Risk)
 
    For Information:   617-724-0857
    Protocol #:   HOD05
    Investigator:   Alison M. Friedmann, MD
    Description:   Intermediate Risk Hodgkin Disease
         
  NON-HODGKIN LYMPHOMA
         
    For Information:   617-724-0857
         
    Protocol #:   COG ANHL01P1
    Investigator:   Howard Weinstein, MD
    Description:   Advanced B-Cell Leukemia/Lymphoma
         
 
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Clinical Trials - Sarcomas
 
  EWING SARCOMA
   
    For Information:   617-724-0857
    Protocol #:   COG AEWS0621
    Investigator:   David H. Ebb, MD
    Description:   Recurrent or Refractory Ewing Sarcoma
   
  OSTEOSARCOMA
 
    For Information:   617-724-0857
 
    Protocol #:   COG AOST0331
    Investigator:   David H. Ebb, MD
    Description:   Newly Diagnosed Osteosarcoma
 
  RHABDOMYOSARCOMA
 
    For Information:   617-724-0857
 
    Protocol #:   COG ARTS0331
    Investigator:   Alison M. Friedmann, MD
    Description:   Low-Risk Rhabdomyosarcoma
 
    For Information:   617-724-0857
 
    Protocol #:   COG ARTS0431
    Investigator:   Alison M. Friedmann, MD
    Description:   High-Risk Rhabdomyosarcoma
 
    For Information:   617-724-0857
 
    Protocol #:   COG ARTS0531
    Investigator:   Alison M. Friedmann, MD
    Description:   Intermediate-Risk Rhabdomyosarcoma
 
    For Information   617-724-0857
 
    Protocol #:   04-188
    Investigator:   Torunn Yock, MD
    Description:   Phase II trial of Proton Radiation for the treatment of Pediatric Rhabdomyosarcoma
 
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Clinical Trials - Other Solid Tumors
 
  GERM CELL TUMORS
   
    For Information:   617-724-0857
   
    Protocol #:   COG AGCT0132
    Investigator:   Mary Huang, MD
    Description:   Low and Intermediate Risk Extracranial Germ Cell Tumors
   
  RENAL TUMORS
 
    For Information:   617-724-0857
 
    Protocol #:   COG AREN0321
    Investigator:   Mary Huang, MD
    Description:   High Risk Renal Tumors
 
    For Information:   617-724-0857
         
    Protocol #:   COG AREN0532
    Investigator:   Mary Huang, MD
    Description:   Low and Standard Risk Favorable Wilms Tumor
 
    For Information:   617-724-0857
 
    Protocol #:   COG AREN0533
    Investigator:   Mary Huang, MD
    Description:   High Risk Favorable Wilms Tumor
 
 
  RETINOBLASTOMA
         
    For Information:   617-724-0857
         
    Protocol #:   COG ARET0332
    Investigator:   Eric Grabowski, MD
    Description:   Unilateral Retinoblastoma
         
    For Information:   617-724-0857
 
    Protocol #:   COG ARET0331
    Investigator:   Eric Grabowski, MD
    Description:   Chemotherapy for Group B Intraocular Retinoblastoma
 
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Harvard Medical School - Teaching Affiliate

 
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