 For Appointments
617-724-4000
Fax
617-724-3166
Office Address
Massachusetts General Hospital Cancer Center
55 Fruit Street, YAW 7B
Boston, MA 02114
Clinical Address
Massachusetts General Hospital Cancer Center
Center for Sarcoma and Connective Tissue Oncology
55 Fruit Street, YAW 3
Boston, MA 02114
Clinical Interests
Sarcoma and Connective Tissue Oncology
Education
MD Degree: New York University School of Medicine, NY, 2000
PhD Degree: New York University School of Medicine, NY, 1999
Postdoctoral Training
Residency: Internal Medicine, Massachusetts General Hospital, Boston, MA
Fellowship: Hematology and Oncology, Dana-Farber Cancer/Partners CancerCare, Boston, MA
Postdoctoral Research Fellowship: Medical and Population Genetics, Broad Institute of MIT and Harvard University, Cambridge, MA
Board Certification
Internal Medicine, 2004
Medical Oncology, 2005
Hospital Appointments
Attending, Hematology & Medical Oncology
Director of Sarcoma Research
Massachusetts General Hospital
Academic Appointments
Instructor in Medicine, Harvard Medical School
Selected Publication
Choy, E., Chiu, V.K., Silletti, J., Feoktistov, M., Morimoto, T., Michaelson, D., Ivanov, I.E., and Philips, M.R. (1999) Endomembrane Trafficking of Ras: the CAAX Motif Targets Proteins to the ER and Golgi. Cell 98, 69-80.
Choy, E. and Philips, M.R. (2001) Green fluorescent protein-tagged Ras proteins for intracellular localization. Methods in Enzymology 332, 50-64.
Dai, Q., Choy, E., Chiu, V., Romano, J., Slivka, S.R., Steitz, S.A., Michaelis, S., and Philips, M.R. (1998) Mammalian Prenylcysteine Prenyltransferase is in the Endoplasmic Reticulum. Journal of Biological Chemistry 273(24), 15030-15034.
Choy, E. and Philips, M.R. (2000) Expression and activity of a prenylcysteine-directed carboxyl methyltransferase. Methods in Enzymology 325, 101-114.
Choy, E., Chiu, V., and Philips, M.R. (1998) The CAAX Motif Targets Proteins to the Endoplasmic Reticulum. Abstract presented to the 38th American Society for Cell Biology Annual Meeting, San Francisco, California. Molecular Biology of the Cell 9, 458a.
Choy, E., Dai, Q., Slivka, S., Steitz, S., and Philips, M.R. (1997) Prenylcysteine Carboxyl Methyltransferase in the ER Directs Ras to the Vesicular Transport Pathway. Abstract presented to the 37th American Society for Cell Biology Annual Meeting, San Francisco, California. Molecular Biology of the Cell 8, 305a.
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