Massachusetts General Hospital Cancer Center
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Sam S. Yoon, MD

For Appointments
617-726-4241

Fax
617-724-3895

Office Address
Massachusetts General Hospital Cancer Center
Division of Surgical Oncology
55 Fruit Street, YAW 7B-7926
Boston, MA 02114

Clinical Interests
Sarcoma, Gastrointestinal Cancers (Stomach & Colorectal), Hepatobiliary Cancers (Liver, Bile Duct, & Pancreas), Melanoma

Laboratory Interests
Surgical Oncology Research Laboratory

Education
MD Degree: University of California, San Diego, CA, 1994

Postdoctoral Training
Residency: Surgery, Massachusetts General Hospital,
Boston, MA
Fellowship: Surgical Oncology, Memorial Sloan-Kettering Cancer Center, New York, NY
Research Fellowship: Massachusetts General Hospital,
Boston, MA

Board Certification
Surgery, 2002

Academic Appointments
Assistant Professor of Surgery, Harvard Medical School

Recent Lectures
Massachusetts General Hospital Surgical Grand Rounds (2005): Gastrointestinal Stromal Tumors
Harvard Medical School Continuing Medical Education Course (2005): Gastric Cancer
Harvard Medical School Continuing Medical Education Course (2004): Soft Tissue Sarcomas

Program/Specialty
Swallowing and Heartburn

My Publications
Link to PubMed Database

Selected Publications
Yoon SS, Segal NH, Park PJ, Detwiller KY, Fernando NT, Ryeom SW, Brennan MF, Singer S. Angiogenic profile of soft tissue sarcomas based on analysis of circulating factors and microarray gene expression. J Surg Res 2006 (in press).

Yoon SS, Tanabe KK. Should surgical resection be combined with imatinib therapy for locally advanced or metastatic gastrointestinal stromal tumors (editorial). Ann Surg Oncol 2006 (in press).

Yoon SS, Segal NH, Brennan MF, Singer S. Circulating angiogenic factor levels correlate with extent of disease and risk of recurrence in patients with soft tissue sarcoma. Ann Oncol 2004:15:1261-1266.

Detwiller KY, Fernando NT, Segal NH, Ryeom SW, D’Amore PA, Yoon SS. Analysis of hypoxia-related gene expression in sarcomas and effect of hypoxia on RNA interference of vascular endothelial cell growth factor A. Cancer Res 2005:65:5881-9.

Yoon SS, Tanabe KK, Warshaw AL. Retroperitoneal teratoma. Surgery 2005:137:663-4.

Yoon SS, Hochberg EP. Chemotherapy is an effective first line treatment for early stage gastric mucosa associated lymphoid tissue lymphoma (editorial). Cancer Treatment Reviews 2006 32:139-143.

Yoon SS, Coit DG, Portlock CS, Karpeh MS. The Diminishing Role of Surgery in the Treatment of Gastric Lymphoma. Ann Surg 2004:240:28-37.

Stipa F, Yoon SS, Liau KH, Fong Y, Jarnagin WR, D’Angelica M, Abou-Alfa G, Blumgart LH, DeMatteo RP. Outcome of patients with fibrolamellar hepatocellular carcinoma. Cancer 2006:106:1331-8.

Yoon SS, Kim SH, Gonen M, Heffernan NM, Detwiller KY, Jarnagin WR, D’Angelica M, Blumgart LH, Tanabe KK, DeMatteo RP. Profile of plasma angiogenic factors before and after hepatectomy for colorectal cancer liver metastases. Ann Surg Oncol 2006:13:353-62.

Tanabe KK, Yoon SS. Surgical and Regional Therapy for Liver Metastases. In: Chang AE, Ganz PA, Hayes D., Kinsella T, Pass HI, Schiller JH, Stone R, Strecher V. Oncology: An Evidence Based Approach. Springer-Verlag, New York. 2006.p.1636-1654.

Tanabe KK, Yoon SS. Benign Liver Tumors. In: Pollock RE, Curley SA, Ross MI, Perrior ND. Advanced Therapy in Surgical Oncology. BC Decker, Hamilton, Canada. 2006 (in press).

Yoon SS, Jarnagin WR, Fong Y, DeMatteo RP, Barakat RR, Blumgart LH, Chi DS. Resection of recurrent ovarian or fallopian tube carcinoma involving the liver. Gynecol Oncol 2003:91:383-8.

Yoon SS, Charny CK, Fong Y, Jarnagin WR, Schwartz LH, Blumgart LH, DeMatteo RP. Diagnosis, management, and outcome of one hundred fifteen patients with hepatic hemangioma. J Amer Coll Surg 2003:197:392-402.

Yoon SS, Tanabe KK. Surgical management of metastatic colon and rectal cancer. In: Steele GD, Phillips TL, Chabner BA, eds, Willet C, series ed. American Cancer Society Atlas of Clinical Oncology: Cancer of the Lower Gastrointestinal Tract BC Decker Inc., Hamilton, Ontario, pp. 170-195, 2001.

Yoon SS, Nakamura H, Carroll NM, Bode BP, Chiocca EA, Tanabe KK. An oncolytic herpes simplex virus type 1 selectively destroys diffuse liver metastases from colon carcinoma. FASEB J 2000:14:301-11.

Yoon SS, Tanabe KK. Surgical treatment and other regional treatments for colorectal cancer liver metastases. Oncologist 1999:4:197-208.

Yoon SS, Tanabe KK. Multidisciplinary management of metastatic colorectal cancer. Surg Oncol 1999:7:197-207.

Yoon SS, Eto H, Lin C-M, Nakamura H, Pawlik TM, Song SU, Tanabe KK. Mouse endostatin inhibits the formation of lung and liver metastases. Cancer Res 1999:59:6251-6.

Yoon SS, Carroll NM, Chiocca EA, Tanabe KK. Influence of p53 on herpes simplex virus type 1 vectors for cancer gene therapy. J Gastrointestinal Surg 1999:3:34-8.

Yoon SS, Carroll NM, Chiocca EA, Tanabe KK. Cancer gene therapy using a replication-competent herpes simplex virus type 1 vector. Ann Surg 1998:228:366-374.

Harvard Medical School - Teaching Affiliate  
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