Massachusetts General Hospital Department of Anesthesia, Critical Care and Pain Medicine - Clinical Research
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Research Overview

Critical Care Research

Pain and Neurosciences Research

Biomedical Innovation

Ethics and Health Policy

Clinical Research

Grant Funding


Critical Care Clinical Research

Summary Science Features

  1. 'Urgent tracheal intubation in general hospital units'.  Benedetto W, et al., Journal of Clinical Anesthesia 2007.  This observational study shows that patients that require emergency intubation of their airway for acute respiratory failure while in the hospital have a high incidence of complications and a high mortality.

  2. 'Effect of supervision on outcomes of emergent airway management'. Schmidt U, et al., manuscript under review.  This observational study shows that the presence of a fully trained anesthesiologist improves outcomes of patients that require emergency intubation of their airway for acute respiratory failure

  3. 'Prolonged cervical immobilization in unconscious trauma patients'.  Stelfox HT, et al.  Journal of Trauma 2007.  Early removal of 'hard collars' for protection of the neck when there is no evidence of neck injury resulted in a significant decrease of complications in the ICU.

  4. Outcome of patients undergoing prolonged mechanical ventilation'. Bigatello L, et al., Critical Care Medicine 2007.  A prospective study of 210 c9onsecutive patients from our Respiratory Acute Care Unit showed that the majority of patients is liberated from the respirator and eventually goes back home.  However, a smaller group of patients does not come off the respirator, and eventually dies after many days in the hospital, often in different units or even different institutions, without ever returning home.

  5. 'Identification of risk factors for occlusion of the tracheostomy tube by the posterior tracheal wall'.  Schmidt U, et al.  Chest, in press.  Approximately 10% of patients that havd difficulty in coming off the respirator had a slightly malpositioned tracheal tube.  Placement of a new tube improved their ability to come off the respirator.

  6. 'Effect of new laboratory testing guidelines on the volume of laboratory tests in a Surgical ICU.'  Kumwilaisak K, et al.  Critical Care Medicine, manuscript under review.  A new set of guidelines aimed at optimize the request of laboratory tests in our ICU resulted in a 30% decrease in the number of tests obtained.  There were no complications and, in some patients, a decreased requirement for blood transfusions
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Office Information

Department of Anesthesia,
Critical Care and Pain Medicine
Gray-Bigelow 444
55 Fruit Street
Boston, MA 02114

Public Transportation Access: Yes
Disabled Access: Yes