Clifford Woolf, MB, BCh, PhD
Position
Director, Neural Plasticity Research Group; Richard J. Kitz Professor of Anesthesia Research, Harvard Medical School
Professional Activities
Our group is devoted to investigating the way in which the functional, chemical and structural plasticity of neurons contributes to adaptive and maladaptive changes in the mammalian nervous
system. Our major efforts are devoted to the study of pain, the formation of neural circuits during development and failure of regeneration of the adult CNS. Most of our work is concentrated on
primary sensory and spinal cord neurons using a multidisciplinary approach spanning genetics, molecular and cell biology, synaptic electrophysiology, neuroanatomy, integrative systems biology
and behavior. We have established several functional and comparative genomic strategies using gain and loss of function approaches to screen for genes involved in neuronal development, pain and regeneration. The group works closely with a wide number of academic groups and the pharmaceutical and biotechnology industry to identify and validate molecular targets for novel analgesics and axonal growth determinants.
Medical Training
University of Witwatersrand, Johannesburg, South Africa
Publications
View Publications
Related Links
Neural Plasticity Research Group
Contact Information
Department of Anesthesia, Critical Care and Pain Medicine
Building 149 13th St
Charlestown, MA 02129
Phone: 617-724-3622
| 
