Joseph F. Cotten, MD, PhD
Instructor, Harvard Medical School
My research focuses on the molecular mechanism by which volatile anesthetics potentiate TASK tandem pore potassium channel function and the role of these pH- and hypoxia-sensitive channels in regulation of breathing. We use an Ussing chamber electrophysiologic system to study these channels and employ a number of molecular techniques, including molecular co-expression, site-directed mutagenesis, and RNA interference. We also use whole-body plethysmography to study breathing.
University of Iowa College of Medicine, MD, PhD
Department of Anesthesia, Critical Care and Pain Medicine
55 Fruit Street
Boston, MA 02114