Massachusetts General Hospital Department of Anesthesia, Critical Care and Pain Medicine - Faculty
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Gary Brenner, MD, PhD

Gary Brenner, MD, PhD

Position

Director, Fellowship in Pain Medicine; Assistant Professor, Harvard Medical School

Clinical Specialty

Chronic Pain, HIV-related Pain

Professional Activities

The aim of my research is to examine changes in dorsal horn NMDA receptor subunit phosphorylation and subcellular distribution during the generation of central sensitization. Central sensitization, an activity-dependent increase in the excitability of dorsal horn neurons generated by C-afferent input, is an important research topic because it is thought to be a primary mechanism responsible for the generation of pathological pain states. In addition, I also investigate intracellular signaling pathways involved in these noxious stimulus-induced NMDA receptor subunit changes and correlate these processes with pain behaviors.

Medical Training

University of Rochester School of Medicine and Dentistry, MD, PhD

Publications

View Publications

Related Links

MGH Pain Center
Neural Plasticity Research Unit

Contact Information

Clinical Office:

Center for Pain Medicine
Massachusetts General Hospital
Wang Ambulatory Care Center, Suite 324
15 Parkman Street Boston, MA 02114
Phone: 617-726-8810
Fax: 617-726-3341

Academic Office:

Division of Pain Medicine
Department of Anesthesia, Critical Care and Pain Medicine
Massachusetts General Hospital
Wang Ambulatory Care Center, Suite 333
15 Parkman Street Boston, MA 02114
Phone: 617-726-3332
Fax: 617-724-2719

Public Transportation Access: Yes
Disabled Access: Yes



 
Office Information

Department of Anesthesia,
Critical Care and Pain Medicine
Gray-Bigelow 444
55 Fruit Street
Boston, MA 02114

Public Transportation Access: Yes
Disabled Access: Yes