Depression Clinical
and Research Program

• All Current Treatment Studies
• Studies for depressed patients not taking any antidepressants
  • A Study of Omega 3-EPA vs. DHA Fatty Acids in the Treatment of Major Depression
  • A Double-Blind, Placebo-Controlled Study of the Alternative Therapy S-adenosyl-L-methionine (SAMe) versus Escitalopram in Major Depressive Disorder
  • Magnetic Resonance Scan (MRS) Study for Depressed Participants
  • Ziprasidone Augmentation Study
• Studies for depressed patients currently taking antidepressants
• Non-treatment studies
• Studies for Smoking Cessation & Relapse Prevention
• Other Studies
• Psychotherapy Studies

Ziprasidone Augmentation Study

The current research study is looking for participants between the ages of 18-65, who are depressed and are not currently taking any medication. If eligible, participants will receive the FDA approved antidepressant medication Escitalopram (Lexapro) for at least 10 weeks. At the end of 10 weeks, subjects who have improved on the medication will be offered 3 months of follow up care at no cost. For those subjects who have NOT improved on the medication, they may be eligible to continue on Lexapro and receive, in addition, either Ziprasidone or placebo. Placebo is sometimes called a sugar pill, and it looks like a study drug but it doesn’t contain any active medication. At the end of the study, all participants will be offered 3 months of follow up care at no cost.

If interested please contact Soo directly at 617-724-2936 or syoun@partners.org

We initiate new studies regularly, so please contact us for additional information.