Members of the Moskowitz Laboratory

Samuel Moskowitz, MD

Sam Moskowitz received his AB summa cum laude from Princeton University in 1986 and his MD magna cum laude in 1994 from Harvard Medical School. His primary research interests lie in the investigation of pediatric pulmonology, particularly in cystic fibrosis and lung infection by Pseudomonas aeruginosa.

Dr. Moskowitz has held academic and clinical positions at the University of Washington School of Medicine and the Seattle Children's Hospital, and is currently affiliated with the MassGeneral Hospital for Children and Harvard Medical School.
Click on his name above for more background information.

  Alina Gutu
Position Postdoctoral Fellow
Education Ph.D. in Biology, Babes-Bolyai University, Cluj-Napoca, Romania
Interests Regulatory mechanism involved in Pseudomonas antibiotic resistance and virulence

My project in the Moskowitz lab deals with characterization of known and novel TCS and other signaling mechanisms involved in Pseudomonas antibiotic resistance and virulence. Besides genetical and biochemical approaches I also use the zebrafish model to further study these signaling pathways in the complex context of host-pathogen interactions.

  Jihye Park
Position Postdoctoral Fellow
Education Ph.D. in Integrative Biosciences (Bioinformatics and Genomics), Pennsylvania State University, University Park, PA
Interests Regulatory mechanisms of Pseudomonas antibiotic resistance, Next-Generation Sequencing (NGS)-based analytical methods, and bioinformatics

My research project seeks to define novel cell wall modifications required for polymyxin (Pm) resistance in Pseudomonas aeruginosa, encompassing both the genetic and biochemical bases of such modifications. I am using Next-Generation Sequencing (NGS)-based methods, including Tn-seq, ChIP-seq, and RNA-seq, to define resistomes, binding targets, and transcriptomes of two-component systems regulating Pm resistance in P. aeruginosa.

  Sylvain Meylan
Position Visiting Scientist
Education M.D. / Ph.D., Ecole polytechnique fédérale de Lausanne, Université de Lausanne, Lausanne, Switzerland
Interests Pseudomonas

    Past Lab Members
    Nicole Sgambati Rodgers (MGH, 2010-2014)
    Sun Ho Kim (Univ. of Washington / MGH, 2008-2014)
    Talia Ramsdell (MGH, 2013-2014)
    Rebecka Nilsson (MGH, 2013-2014)
    Samuel Kitara (MGH, 2013)
    Danilo Xavier (MGH, 2011-2012)
    Nandini Dasgupta (MGH, 2010-2012)
    Heidi Burke (Univ. of Washington / MGH, 2008-2011)
    Mark Brannon (Univ. of Washington, 2004-2009)
    Amanda Weeks (Univ. of Washington, 2006-2008)
    Pnina Strasbourger (Univ. of Washington, 2005-2008)
    Miyuki Pier (Univ. of Washington, 2003-2007)
    Laurel Stevens (Univ. of Washington, 2003-2005)
    Lillian Yeung (Univ. of Washington, 2003-2004)
    Maxine Smith (Univ. of Washington, 2001-2009), fiscal manager

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